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Results for "

SOD1

" in MedChemExpress (MCE) Product Catalog:

14

Inhibitors & Agonists

1

Peptides

2

Recombinant Proteins

1

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-123982

    Others Neurological Disease
    SOD1-Derlin-1 inhibitor-2 (compound 56-59) is an inhibitor of SOD1-Derlin-1 interaction. SOD1-Derlin-1 inhibitor-2 attenuates the interactions between Derlin-1 and SOD1 mut. SOD1-Derlin-1 inhibitor-2 can be used for the research of amyotrophic lateral sclerosis (ALS) [1].
    SOD1-Derlin-1 inhibitor-2
  • HY-138131

    Others Neurological Disease
    SOD1-Derlin-1 inhibitor-1 (compound 56-20) is an inhibitor of SOD1-Derlin-1 interaction. SOD1-Derlin-1 inhibitor-1 inhibits SOD1 G93A-Derlin-1 complex with an IC50 value of 7.11 μM. SOD1-Derlin-1 inhibitor-1 can be used for the research of amyotrophic lateral sclerosis [1].
    SOD1-Derlin-1 inhibitor-1
  • HY-132580A

    BIIB067 SODium; ISIS-SOD1Rx SODium

    DNA/RNA Synthesis Neurological Disease
    Tofersen sodium is an antisense oligonucleotide that mediates RNase H-dependent degradation of superoxide dismutase 1 (SOD1) mRNA to reduce the synthesis of SOD1 protein. Tofersen sodium can be used for the research of amyotrophic lateral sclerosis (ALS) [1].
    Tofersen sodium
  • HY-153019

    SOD Neurological Disease
    NUCC-0000323 is a potent superoxide dismutase 1 (SOD1) inhibitor. NUCC-0000323 inhibits SOD1 expression. NUCC-0000323 can be used in research of amyotrophic lateral sclerosis (ALS) [1].
    NUCC-0000323
  • HY-16074
    ATN-224
    3 Publications Verification

    Bis(choline)tetrathiomolybdate

    SOD Cancer
    ATN-224 is an oral Cu 2+/Zn 2+-superoxide dismutase 1 (SOD1) inhibitor. ATN-224 inhibits SOD1 activity in endothelial cells, an effect that is dose dependent with an IC50 of 17.5±3.7 nM.
    ATN-224
  • HY-115445
    LCS-1
    1 Publications Verification

    Apoptosis SOD Cancer
    LCS-1 is a superoxide dismutase 1 (SOD1) inhibitor. LCS-1 inhibits SOD1 activity with an IC50 value of 1.07 μM. LCS-1 induces the early- and late-stage apoptosis of multiple myeloma (MM.1S) cells [1] .
    LCS-1
  • HY-P10627

    Amyloid-β Neurological Disease
    SOD1 (147-153) human is a peptide fragment of Cu/Zn superoxide dismutase (SOD1) with a high propensity to form amyloid fibrils. SOD1 (147-153) human may trigger the aggregation of full-length SOD1 and is a common molecular determinant of familial amyotrophic lateral sclerosis (fALS) and sporadic amyotrophic lateral sclerosis (sALS) [1].
    SOD1 (147-153) human
  • HY-RS13559

    Small Interfering RNA (siRNA) Others

    SOD1 Human Pre-designed siRNA Set A contains three designed siRNAs for SOD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SOD1 Human Pre-designed siRNA Set A
    SOD1 Human Pre-designed siRNA Set A
  • HY-132580

    BIIB067; ISIS-SOD1Rx

    DNA/RNA Synthesis Neurological Disease
    Tofersen (BIIB067) is an antisense oligonucleotide that mediates RNase H-dependent degradation of superoxide dismutase 1 (SOD1) mRNA to reduce the synthesis of SOD1 protein. Tofersen can be used for the research of amyotrophic lateral sclerosis (ALS) [1].
    Tofersen
  • HY-E70377

    Cu/Zn SOD

    SOD Inflammation/Immunology Cancer
    Cu/Zn Superoxide dismutase (Cu/Zn SOD; SOD1) is a cytosolic copper-zinc dimer form of superoxide dismutase enzyme. Cu/Zn Superoxide dismutase has oxygen radical enzymatic dismutation [1].
    Cu/Zn Superoxide dismutase
  • HY-148901

    COX Neurological Disease
    CMB-087229 is a mutant superoxide dismutase 1 (SOD1) protein aggregation inhibitor with IC50 of 67 nM, which can be used in the research of amyotrophic lateral sclerosis [1].
    CMB-087229
  • HY-145294

    ROCK Neurological Disease
    ROCK2-IN-5 (compound 1d) is a hybrid compound containing structural fragments of the Rho kinase inhibitor fasudil and the NRF2 inducers caffeic and ferulic acids. ROCK2-IN-5 has good multitarget profile and good tolerability. ROCK2-IN-5 has the potential for thr research of Amyotrophic lateral sclerosis (ALS) with a SOD1 mutation [1].
    ROCK2-IN-5
  • HY-163772

    Keap1-Nrf2 Neurological Disease
    Fraxinellone analog 1 (compound 2) is a potent and rapid activator of the Nrf2 mediated antioxidant defense system, which protects against glutamate-mediated excitotoxicity and induces the expression of antioxidant genes Gpx4, Sod1, and Nqo1. Fraxinellone analog 1 has neuroprotective effects and regulatory effects against oxidative stress and inflammation, and can be used in the study of neurodegenerative diseases [1].
    Fraxinellone analog 1
  • HY-W115718
    Cuprizone
    1 Publications Verification

    Dopamine β-hydroxylase Neurological Disease
    Cuprizone is a copper chelating agent that forms a deep blue copper ketone complex with copper (II). The copper ketone reaction can be used in colorimetric tests for the presence of trace copper. Cuprizone can be used to induce some schizophrenia-like behavior in mice. Cuprizone acts on copper enzymes, including SOD1, cytochrome oxidase, and DβH, thereby causing oxidative stress and increasing DA levels in certain brain regions such as the medial prefrontal cortex (PFC) [1].
    Cuprizone

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