SRM

By Targets:	Autophagy (3) Drug Metabolite (2) Fluorescent Dye (4) Isotope-Labeled Compounds (1) p38 MAPK (4) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (3) Inflammation/Immunology (3) Neurological Disease (4)
Click Chemistry:	Azide (1)
Oligonucleotides:	Pre-designed siRNA Sets (2) siRNAs (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-120111

MW-150 MW01-18-150SRM	p38 MAPK Autophagy	Neurological Disease Inflammation/Immunology
MW150 (MW01-18-150SRM) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a K_i of 101 nM. MW-150 inhibits the ability of the endogenous p38α MAPK to phosphorylate an endogenous substrate MK2 in activated glia .

HY-P3146A

FTISADTSK acetate	Drug Metabolite	Cancer
FTISADTSK acetate is an endogenous stable signature peptide from Trastuzumab monitored by selected reaction monitoring (SRM) .

HY-P3146S

FTISADTSK-13C6,15N2 TFA	Isotope-Labeled Compounds	Cancer
FTISADTSK- ¹³C₆, ¹⁵N₂ TFA is ¹³C- and ¹⁵N-labeled FTISADTSK (HY-P3146). FTISADTSK is an endogenous stable signature peptide from Trastuzumab monitored by selected reaction monitoring (SRM) .

HY-131029

Janelia Fluor® 646, Maleimide JF646, Maleimide	Fluorescent Dye	Others
Janelia Fluor® 646, Maleimide (JF646, Maleimide) is a red fluorescent dye that contains a maleimide group. JF646, Maleimide can be used in cellular imaging . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-RS13769

SRM Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SRM Human Pre-designed siRNA Set A contains three designed siRNAs for SRM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SRM Human Pre-designed siRNA Set A SRM Human Pre-designed siRNA Set A

HY-RS13770

SRMS Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SRMS Human Pre-designed siRNA Set A contains three designed siRNAs for SRMS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SRMS Human Pre-designed siRNA Set A SRMS Human Pre-designed siRNA Set A

HY-120111A

MW-150 hydrochloride MW01-18-150SRM hydrochloride	p38 MAPK Autophagy	Neurological Disease Inflammation/Immunology
MW-150 hydrochloride (MW01-18-150SRM hydrochloride) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a K_i of 101 nM. MW-150 hydrochloride (MW01-18-150SRM hydrochloride) inhibits the ability of the endogenous p38α MAPK to phosphorylate an endogenous substrate MK2 in activated glia .

HY-120111B

MW-150 dihydrochloride dihydrate MW01-18-150SRM dihydrochloride dihydrate	p38 MAPK Autophagy	Neurological Disease Inflammation/Immunology
MW-150 dihydrochloride dihydrate (MW01-18-150SRM dihydrochloride dihydrate) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a K_i of 101 nM. MW-150 dihydrochloride dihydrate (MW01-18-150SRM dihydrochloride dihydrate) inhibits the ability of the endogenous p38α MAPK to phosphorylate an endogenous substrate MK2 in activated glia .

HY-120796

MW108 hydrochloride MW01-11-108SRM hydrochloride	p38 MAPK	Neurological Disease
MW108 (MW01-11-108SRM) hydrochloride is a selective and CNS-penetrant p38αMAPK inhibitor with a K_i of 114 nM. MW108 hydrochloride ameliorates beta-amyloid induced synaptic and cognitive dysfunction .

HY-P3146

FTISADTSK	Drug Metabolite	Cancer
FTISADTSK is an endogenous stable signature peptide from Trastuzumab monitored by selected reaction monitoring (SRM) .

HY-131028

Janelia Fluor® 646 TFA JF646 TFA	Fluorescent Dye	Others
Janelia Fluor® 646 TFA (JF646 TFA), a red fluorogenic fluorescent dye, can be used in the synthesis of Janelia Fluor 646 HaloTag and SNAP-Tag ligands. JF646 TFA is used in live cell imaging experiments . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-131026

Janelia Fluor® 635, SE JF635, SE; JF635, NHS	Fluorescent Dye	Others
Janelia Fluor® 635, SE (JF635, SE) is a red fluorogenic fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. JF635, SE can be used for live cell imaging . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-152901

Chol-N3	Fluorescent Dye	Others
Chol-N3 is a bioorthogonal-based chol probe. Chol-N3 can combine with super-resolution fluorescence microscopy (SRM), providing direct visualization of nanoscale lipid heterogeneity in the cell surface of resting living cells . Chol-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No.	Product Name	Type

HY-131029

Janelia Fluor® 646, Maleimide JF646, Maleimide	Fluorescent Dyes/Probes
Janelia Fluor® 646, Maleimide (JF646, Maleimide) is a red fluorescent dye that contains a maleimide group. JF646, Maleimide can be used in cellular imaging . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-131028

Janelia Fluor® 646 TFA JF646 TFA	Fluorescent Dyes/Probes
Janelia Fluor® 646 TFA (JF646 TFA), a red fluorogenic fluorescent dye, can be used in the synthesis of Janelia Fluor 646 HaloTag and SNAP-Tag ligands. JF646 TFA is used in live cell imaging experiments . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-131026

Janelia Fluor® 635, SE JF635, SE; JF635, NHS	Dyes
Janelia Fluor® 635, SE (JF635, SE) is a red fluorogenic fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. JF635, SE can be used for live cell imaging . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

Cat. No.	Product Name	Target	Research Area

HY-P3146A

FTISADTSK acetate	Drug Metabolite	Cancer
FTISADTSK acetate is an endogenous stable signature peptide from Trastuzumab monitored by selected reaction monitoring (SRM) .

HY-P3146S

FTISADTSK-13C6,15N2 TFA	Isotope-Labeled Compounds	Cancer
FTISADTSK- ¹³C₆, ¹⁵N₂ TFA is ¹³C- and ¹⁵N-labeled FTISADTSK (HY-P3146). FTISADTSK is an endogenous stable signature peptide from Trastuzumab monitored by selected reaction monitoring (SRM) .

HY-P3146

FTISADTSK	Drug Metabolite	Cancer
FTISADTSK is an endogenous stable signature peptide from Trastuzumab monitored by selected reaction monitoring (SRM) .

Cat. No.	Product Name	Chemical Structure

HY-P3146S

FTISADTSK-13C6,15N2 TFA
FTISADTSK- ¹³C₆, ¹⁵N₂ TFA is ¹³C- and ¹⁵N-labeled FTISADTSK (HY-P3146). FTISADTSK is an endogenous stable signature peptide from Trastuzumab monitored by selected reaction monitoring (SRM) .

Cat. No.	Product Name		Classification

HY-152901

Chol-N3		Azide
Chol-N3 is a bioorthogonal-based chol probe. Chol-N3 can combine with super-resolution fluorescence microscopy (SRM), providing direct visualization of nanoscale lipid heterogeneity in the cell surface of resting living cells . Chol-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No.	Product Name		Classification

HY-RS13769

SRM Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
SRM Human Pre-designed siRNA Set A contains three designed siRNAs for SRM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS13770

SRMS Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
SRMS Human Pre-designed siRNA Set A contains three designed siRNAs for SRMS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
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Inhibitors & Agonists

Fluorescent Dye

Peptides

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

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