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Results for "

anti-tumor promoters

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

5

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-135691
    hnRNPK-IN-1

    		c-Myc Apoptosis Cancer
    hnRNPK-IN-1 is a heterogeneous nuclear ribonucleoprotein K (hnRNPK) binding ligand with Kd values of 4.6 μM and 2.6 μM measured with SPR and MST, respectively. hnRNPK-IN-1 inhibits c-myc transcription by disrupting the binding of hnRNPK and c-myc promoter. hnRNPK-IN-1 induces Hela cells apoptosis and has strongly anti-tumor activities .
    hnRNPK-IN-1
  • HY-122486
    Lophirachalcone

    Lophirochalcone

    		 Others Cancer
    Lophirachalcone (Lophirochalcone) is an inhibitor of the activation of EB virus (EBV) induced by tumor promoter teleocidin B-4. Lophirachalcone has antitumor activity .
    Lophirachalcone
  • HY-N12978
    Benzyl β-gentiobioside

    		Others Cancer
    Benzyl β-gentiobioside is a phenyl alcohol glycoside found in peach kernels (Prunus persica seeds). Benzyl β-gentiobioside has anti-tumor promoting activity by inhibiting TPA (12-O-tetradecanoylphorbol 13-acetate, a tumor promoter)-induced Epstein-Barr virus early antigen (EBV-EA) activation .
    Benzyl β-gentiobioside
  • HY-N8714
    Interiotherin C

    Rubriflorin A

    		 Biochemical Assay Reagents Inflammation/Immunology Cancer
    Interiotherin C is an antitumor promoter and also has anti-inflammatory activity. Interiotherin C is a new lignin that can be obtained from Kadsurainterior. Interiotherin C is used in cancer and inflammation research .
    Interiotherin C
  • HY-N8873
    Silychristin B

    		Others Cancer
    Silychristin B is an antitumor promoter. Silychristin B inhibits TPA induced Epstein-Barr virus early antigen (EBV-EA) induction. Silychristin B can be isolated from milk thistle .
    Silychristin B
  • HY-N12486A
    (3S,8R,9R)-Isofalcarintriol

    		Others Neurological Disease Metabolic Disease Cancer
    (3S,8R,9R)-Isofalcarintriol is a natural polyacetylene compound found in carrot root parts. (3S,8R,9R)-Isofalcarintriol is a potent longevity promoter that improves glucose metabolism and has anti-tumor activity. (3S,8R,9R)-Isofalcarintriol can affect cellular respiration, interact with the α subunit of mitochondrial ATP synthase, and promote mitochondrial biogenesis. (3S,8R,9R)-Isofalcarintriol can be used in the study of neurodegenerative diseases, metabolic diseases, and aging .
    (3S,8R,9R)-Isofalcarintriol
  • HY-N7563
    α-Toxicarol

    		EBV Infection Cancer
    α-Toxicarol is a potent inhibitor of EBV.α-Toxicarol significantly inhibits mouse skin tumor in vivo. α-Toxicarol inhibits the TPA-induced EBV-EA activation .
    α-Toxicarol
  • HY-15186C
    Ipatasertib tosylate

    GDC-0068 tosylate; RG7440 tosylate

    		 Akt Cancer
    Ipatasertib (GDC-0068) (tosylate) is a highly selective ATP-competitive pan-Akt inhibitor with antitumor effects. Ipatasertib (tosylate) prevents colon cancer growth through p53-independent p53 upregulated modulator of apoptosis (PUMA) dependent Apoptosis. Ipatasertib (tosylate) leads to PUMA activation by inhibiting Akt, thereby activating both FoxO3a and NF-κB synchronously that will directly bind to PUMA promoter, up-regulating PUMA transcription and Bax-mediated intrinsic mitochondrial Apoptosis .
    Ipatasertib tosylate
  • HY-119009
    TM-233

    		JAK STAT NF-κB Bcl-2 Family Cancer
    TM-233 is an inhibitor of the JAK/STAT and NF-κB signaling pathways, exhibiting significant antitumor activity. TM-233 reduces the expression of the anti-apoptotic protein Mcl-1 by inhibiting the phosphorylation of JAK2 and STAT3, and regulates its transcription by directly binding to the Mcl-1 gene promoter. Additionally, TM-233 prevents the translocation of NF-κB from the cytoplasm to the nucleus by inhibiting its DNA-binding activity, thereby reducing nuclear NF-κB expression. TM-233 shows potential in overcoming Bortezomib (HY-10227) resistance and can be applied in research related to multiple myeloma .
    TM-233

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