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antibacterial metabolite

" in MedChemExpress (MCE) Product Catalog:

45

Inhibitors & Agonists

1

Biochemical Assay Reagents

16

Natural
Products

5

Isotope-Labeled Compounds

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101411
    4-Acetamidobutanoic acid
    1 Publications Verification

    N-acetyl GABA

    		 GABA Receptor Endogenous Metabolite Bacterial Others
    4-Acetamidobutanoic acid (N-acetyl GABA), the main metabolite of GABA, exhibits antioxidant and antibacterial activities .
    4-Acetamidobutanoic acid
  • HY-N6711A
    epi-Equisetin

    		Bacterial Infection
    epi-Equisetin, a secondary metabolite, has antibacterial activity .
    epi-Equisetin
  • HY-100622
    Ro 20-0657/000

    		Bacterial Infection
    Ro 20-0657/000 is a metabolite of Trimethoprim. Trimethoprim is a dihydrofolate reductase inhibitor, used as an antibacterial agent in human and veterinary medicine .
    Ro 20-0657/000
  • HY-N8406
    Monomethylsulochrin

    		Bacterial Antibiotic Infection
    Monomethylsulochrin is a potent antibacterial metabolite from endophytic fungus Aspergillus fumigatus, isolated from Albizia lucidior leaves (fabaceae). Monomethylsulochrin exhibits anti-Staphylococcus aureus activity with minimum inhibitory concentration (MIC) of 31.25 μg/mL .
    Monomethylsulochrin
  • HY-N10227
    Geodin

    		PAI-1 Antibiotic Infection Inflammation/Immunology
    Geodin, a fungal metabolite, shows antibacterial activity. Geodin also is an inhibitor of plasminogen activator inhibitor- 1 (PAI-1) .
    Geodin
  • HY-N10282
    Isodihydroauroglaucin

    		Fungal Bacterial Endogenous Metabolite Infection
    Isodihydroauroglaucin, a fungal metabolite, shows antibacterial activity .
    Isodihydroauroglaucin
  • HY-123036
    Renierone

    		Bacterial Infection
    Renierone is an antibacterial metabolite found in the sponge Reniera sp. .
    Renierone
  • HY-W006449
    PNU-105368

    		Others Others
    PNU-105368 is a compound with antibacterial activity and a metabolite of linezolid. It exists mainly in the form of the original form and two metabolites in the human body and is excreted through the kidneys and feces.
    PNU-105368
  • HY-130046
    16-Epiestriol

    16-epi-Estriol; 16β,17β-Estriol

    		 Bacterial Infection Inflammation/Immunology
    16-Epiestriol is a metabolite of the endogenous estrogen estrone with antibacterial and anti-inflammatory effects[1][2][3].
    16-Epiestriol
  • HY-142075
    Antibacterial agent 134

    		Bacterial Infection
    Antibacterial agent 134 (compound 1) is an diketopiperazine alkaloid with antimicrobial activity. Antibacterial agent 134 is the major metabolite in the culture of Hymeniacidon perleve associated bioactive bacterium Pseudomonas sp. NJ6-3-1 .
    Antibacterial agent 134
  • HY-131557
    O-Deacetylravidomycin

    		Antibiotic Bacterial Infection
    O-Deacetylravidomycin, a microbial metabolite discovered in Streptomyces, is an antibiotic. O-Deacetylravidomycin exhibits light-dependent antibacterial and anticancer activities .
    O-Deacetylravidomycin
  • HY-135389
    Desmethyl Levofloxacin

    		Drug Metabolite Antibiotic Infection
    Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication .
    Desmethyl Levofloxacin
  • HY-108279
    Ulifloxacin

    		Antibiotic Bacterial Infection
    Ulifloxacin is a broad-spectrum quinolone antibiotic. Ulifloxacin is the active metabolite of Prulifloxacin (HY-B0024). Ulifloxacin has anti-bacterial activity .
    Ulifloxacin
  • HY-W403633
    Hexahydrohippuric acid

    		Bacterial Infection
    Hexahydrohippuric acid is a metabolite of Shikimate acid in both liver and kidney, under microbial metabolism effect. Hexahydrohippuric acid is made of cyclohexane carboxylic acid and glycinamide, and shows antibacterial activity .
    Hexahydrohippuric acid
  • HY-137263
    Propionylmaridomycin

    		Antibiotic Infection
    Propionylmaridomycin is a macrolide antibiotic with antibacterial activity. Propionylmaridomycin is rapidly absorbed from the gastrointestinal tract and rapidly distributed to tissues. Propionylmaridomycin radioactivity levels in the liver, kidneys, and lungs were significantly higher than in plasma, while distribution to the brain was less. Propionylmaridomycin is excreted primarily through the feces, and the high fecal recovery rate is due to unabsorbed compounds and biliary excretion of compounds and their metabolites. Propionylmaridomycin exhibits the highest antibacterial activity in the lungs. Propionylmaridomycin is completely converted to several metabolites in rats, of which 4''-depropionyl-9-propionylmaridomycin was identified as the major metabolite .
    Propionylmaridomycin
  • HY-122139
    Desethylene Ciprofloxacin hydrochloride

    		Bacterial Infection
    Desethylene Ciprofloxacin hydrochloride is a major metabolite of Ciprofloxacin (HY-B0356). Ciprofloxacin is an orally active topoisomerase IV inhibitor. Desethylene Ciprofloxacin hydrochloride has antibacterial activity .
    Desethylene Ciprofloxacin hydrochloride
  • HY-139558
    Zapnometinib

    PD0184264; ATR-002

    		 MEK Influenza Virus Bacterial Infection Cancer
    Zapnometinib (PD0184264), an active metabolite of CI-1040, is a MEK inhibitor, with an IC50 of 5.7 nM. Zapnometinib exhibits antiviral activity against influenza virus and antibacterial activities .
    Zapnometinib
  • HY-130049
    Lucidin ω-ethyl ether

    		Bacterial Infection
    Lucidin ω-ethyl ether (compound 17) is an anthraquinone metabolite isolated from the root part of Prismatomeris filamentosa with some antibacterial activity against Gram-positive and Gram-negative bacteria .
    Lucidin ω-ethyl ether
  • HY-N8846
    dl-Aloesol

    		Fungal Infection
    dl-Aloesol is a natural product that can be isolated from fungus Aspergillus sp. Aspergillus sp metabolites has cytotoxic, antibacterial, free radical scavenging, anti-parasitic, antiviral and antiproliferative activities, etc .
    dl-Aloesol
  • HY-129315
    Deacylketoconazole

    N-Deacetylketoconazole; R-39519

    		 Bacterial Fungal Infection
    Deacylketoconazole (N-Deacetylketoconazole; R-39519) is an orally active metabolite of Ketoconazole (HY-B0105). Deacylketoconazole exhibits antifungal and antibacterial activity. Deacylketoconazole is cytotoxic in rats hepatocyte .
    Deacylketoconazole
  • HY-100711
    Prodigiosin
    1 Publications Verification

    Prodigiosine; NSC47147

    		 Bacterial Apoptosis Wnt Fungal Parasite Infection Inflammation/Immunology Cancer
    Prodigiosin (Prodigiosine) is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin is a potent inhibitor of the Wnt/β-catenin pathway. Prodigiosin has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties .
    Prodigiosin
  • HY-135389S
    Desmethyl Levofloxacin-d8 hydrochloride

    		Isotope-Labeled Compounds Drug Metabolite Antibiotic Infection
    Desmethyl Levofloxacin-d8 hydrochloride is the deuterium labeled Desmethyl Levofloxacin. Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication .
    Desmethyl Levofloxacin-d8 hydrochloride
  • HY-130046R
    16-Epiestriol (Standard)

    		Endogenous Metabolite Bacterial Infection Inflammation/Immunology
    16-Epiestriol (Standard) is the analytical standard of 16-Epiestriol. This product is intended for research and analytical applications. 16-Epiestriol is a metabolite of the endogenous estrogen estrone with antibacterial and anti-inflammatory effects .
    16-Epiestriol (Standard)
  • HY-100711A
    Prodigiosin hydrochloride
    1 Publications Verification

    Prodigiosine hydrochloride

    		 Bacterial Apoptosis Fungal Wnt Parasite Infection Inflammation/Immunology Cancer
    Prodigiosin (Prodigiosine) hydrochloride is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin hydrochloride is a potent proapoptotic agent, and inhibits Wnt/β-catenin pathway. Prodigiosin hydrochloride has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties .
    Prodigiosin hydrochloride
  • HY-135389S1
    Desmethyl Levofloxacin-d8

    		Isotope-Labeled Compounds Drug Metabolite Antibiotic Infection
    Desmethyl Levofloxacin-d8 is deuterium labeled Desmethyl Levofloxacin. Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication[1].
    Desmethyl Levofloxacin-d8
  • HY-101411S
    4-Acetamidobutanoic acid-d3

    N-acetyl GABA-d3

    		 Bacterial GABA Receptor Endogenous Metabolite Isotope-Labeled Compounds Others
    4-Acetamidobutanoic acid-d3 is the deuterated analog of 4-Acetamidobutanoic acid (HY-101411). 4-Acetamidobutanoic acid (N-acetyl GABA), the main metabolite of GABA, exhibits antioxidant and antibacterial activities .
    4-Acetamidobutanoic acid-d3
  • HY-108279R
    Ulifloxacin (Standard)

    		Antibiotic Bacterial Infection
    Ulifloxacin (Standard) is the analytical standard of Ulifloxacin. This product is intended for research and analytical applications. Ulifloxacin is a broad-spectrum quinolone antibiotic. Ulifloxacin is the active metabolite of Prulifloxacin (HY-B0024). Ulifloxacin has anti-bacterial activity .
    Ulifloxacin (Standard)
  • HY-118118
    Phlebiakauranol aldehyde

    		Fungal Infection
    Phlebiakauranol aldehyde is an antifungal and cytotoxic metabolite with strong antifungal activity. Phlebiakauranol aldehyde exhibits significant antibacterial and cytotoxic activities against a variety of plant pathogens. The aldehyde group and high number of hydroxyl groups of Phlebiakauranol aldehyde are considered to be the main reasons for its biological activity. The two acetic acid derivatives of Phlebiakauranol aldehyde only exhibit very weak antifungal and antibacterial activities and moderate cytotoxic activity .
    Phlebiakauranol aldehyde
  • HY-136440
    Hydroxymetronidazole

    Metronidazole-OH

    		 Bacterial Parasite Infection
    Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
    Hydroxymetronidazole
  • HY-136440S1
    Hydroxymetronidazole-d2

    Metronidazole-OH-d2

    		 Isotope-Labeled Compounds Infection
    Hydroxymetronidazole-d2 is the deuterium labeled Hydroxymetronidazole(HY-136440).Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
    Hydroxymetronidazole-d2
  • HY-136440R
    Hydroxymetronidazole (Standard)

    		Bacterial Parasite Infection
    Hydroxymetronidazole (Standard) is the analytical standard of Hydroxymetronidazole. This product is intended for research and analytical applications. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
    Hydroxymetronidazole (Standard)
  • HY-B0212
    Sulfapyridine

    		Bacterial Antibiotic Infection Inflammation/Immunology
    Sulfapyridine, a major metabolite of Sulfasalazine, is a sulfonamide antibiotic agent. Sulfapyridine inhibits recombinant P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM. Sulfapyridine has antibacterial, anti-inflammatory and anti-rheumatic activities .
    Sulfapyridine
  • HY-111278
    Pyocyanin
    1 Publications Verification

    Pyocyanine; Sanazin; Sanasin

    		 Reactive Oxygen Species Bacterial Drug Metabolite Infection Inflammation/Immunology
    Pyocyanin (Pyocyanine) is a toxic, quorum sensing (QS) controlled metabolite produced by Pseudomonas aeruginosa. Pyocyanin is a REDOX active compound that promotes the production of reactive oxygen species (ROS). Pyocyanin has antibacterial and anti-inflammatory activity .
    Pyocyanin
  • HY-135389R
    Desmethyl Levofloxacin (Standard)

    		Drug Metabolite Antibiotic Infection
    Desmethyl Levofloxacin (Standard) is the analytical standard of Desmethyl Levofloxacin. This product is intended for research and analytical applications. Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication .
    Desmethyl Levofloxacin (Standard)
  • HY-122139R
    Desethylene Ciprofloxacin hydrochloride (Standard)

    		Bacterial Infection
    Desethylene Ciprofloxacin (hydrochloride) (Standard) is the analytical standard of Desethylene Ciprofloxacin (hydrochloride). This product is intended for research and analytical applications. Desethylene Ciprofloxacin hydrochloride is a major metabolite of Ciprofloxacin (HY-B0356). Ciprofloxacin is an orally active topoisomerase IV inhibitor. Desethylene Ciprofloxacin hydrochloride has antibacterial activity .
    Desethylene Ciprofloxacin hydrochloride (Standard)
  • HY-121178
    Deoxyviolacein

    		Others Infection
    Deoxyviolacein is a bacterial metabolite and byproduct in the biosynthesis of the bisindole alkaloid violacein (HY-119809) that has anticancer, antibacterial, and antifungal properties. It inhibits proliferation of hepatocellular carcinoma cells when used at concentrations ranging from 0.1 to 1 μM. Deoxyviolacein (125 μg/mL) has antibacterial activity against Gram-positive bacteria, including S. aureus, B. subtilis, and B. megaterium. It also has antifungal activity against R. solani when used at a concentration of 2 mg/ml.
    Deoxyviolacein
  • HY-B0212R
    Sulfapyridine (Standard)

    		Bacterial Antibiotic Infection Inflammation/Immunology
    Sulfapyridine (Standard) is the analytical standard of Sulfapyridine. This product is intended for research and analytical applications. Sulfapyridine, a major metabolite of Sulfasalazine, is a sulfonamide antibiotic agent. Sulfapyridine inhibits recombinant P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM. Sulfapyridine has antibacterial, anti-inflammatory and anti-rheumatic activities .
    Sulfapyridine (Standard)
  • HY-N1029
    Norathyriol

    Mangiferitin

    		 Glucosidase PPAR Infection Inflammation/Immunology Cancer
    Norathyriol (Mangiferitin) is a natural metabolite of Mangifera. Norathyriol inhibits α-glucosidase in a noncompetitive manner with an IC50 of 3.12 μM . Norathyriol inhibits PPARα, PPARβ, and PPARγ with IC50s of 92.8 µM, 102.4 µM, and 153.5 µM, respectively . Antioxidant, anticancer, antimicrobial, anti-inflammatory, anti-bacterial activities.
    Norathyriol
  • HY-N12231
    Carbazomycin B

    		Antibiotic Bacterial Lipoxygenase Infection Cancer
    Carbazomycin B is a bacterial metabolite and can be isolated from Streptomyces. Carbazomycin B is an antifungal and antibacterial agent. Carbazomycin B inhibits 5-lipoxygenase (5-LO) activity in extract from RBL-1 cell with the IC50 Of 1.5 µM sup>[2]sup>[3]sup>[4].
    Carbazomycin B
  • HY-W272217
    Octacosane

    n-Octacosane; NSC 5549

    		 Endogenous Metabolite Bacterial Inflammation/Immunology Cancer
    Octacosane is an endogenous metabolite with antibacterial activity. Octacosane shows high cytotoxicity against murine melanoma B16F10-Nex2 cells besides inducing protection against a grafted subcutaneous melanoma. Octacosane has the larvicidal activity against mosquito Culex quinquefasciatus with the LC50 concentration of 7.2 mg/l .
    Octacosane
  • HY-W272217S
    Octacosane-d58

    n-Octacosane-d58; NSC 5549-d58

    		 Bacterial Endogenous Metabolite Cancer
    Octacosane-d58 is the deuterium labeled Octacosane[1]. Octacosane is an endogenous metabolite with antibacterial activity. Octacosane shows high cytotoxicity against murine melanoma B16F10-Nex2 cells besides inducing protection against a grafted subcutaneous melanoma. Octacosane has the larvicidal activity against mosquito Culex quinquefasciatus with the LC50 concentration of 7.2 mg/l[2][3][4].
    Octacosane-d58
  • HY-W272217R
    Octacosane (Standard)

    		Endogenous Metabolite Bacterial Inflammation/Immunology Cancer
    Octacosane (Standard) is the analytical standard of Octacosane. This product is intended for research and analytical applications. Octacosane is an endogenous metabolite with antibacterial activity. Octacosane shows high cytotoxicity against murine melanoma B16F10-Nex2 cells besides inducing protection against a grafted subcutaneous melanoma. Octacosane has the larvicidal activity against mosquito Culex quinquefasciatus with the LC50 concentration of 7.2 mg/l .
    Octacosane (Standard)
  • HY-N8256
    (–)-Mycousnine

    Mycousunin

    		 Others Infection
    (–)-Mycousnine is a microbial metabolite and derivative of Usnic Acid (HY-N0656) originally isolated from M. nawae that has antibacterial and antifungal activities. It is active against the Gram-positive bacteria B. subtilis, K. rhizophila, and S. aureus (MICs=4, 8, and 4 g/ml, respectively) but not the Gram-negative bacteria E. coli, S. typhimurium, and K. pneumoniae (MICs=>128 g/ml for all).2 (–)-Mycousnine is also active against the fungi T. mentagrophytes, T. rubrum, and C. albicans (MICs=25, 25, and 100 μg/mL, respectively).
    (–)-Mycousnine
  • HY-126619
    Aspochalasin D

    		Others Infection
    Aspochalasin D is a co-metabolite originally isolated from A. microcysticus with aspochalasins A, B, and C, that is initially thought to be inactive. It has antibacterial activity against Gram-positive and Gram-negative bacteria at a concentration of 1 mg/ml.2 Aspochalasin D is more cytotoxic, via apoptosis, to Ba/F3-V12 cells in an IL-3-free medium than in an IL-3-containing medium (IC50s=0.49 and 1.9 μg/mL, respectively).
    Aspochalasin D
  • HY-138185
    Collismycin A

    SF 2738A

    		 Bacterial Infection
    Collismycin A is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities, including antibacterial, antiproliferative, and neuroprotective properties. It is active against a variety of bacteria (MICs=6.25 and 100 μg/mL) and fungi (MICs=12.5-100 μg/mL). It inhibits proliferation of A549 lung, HCT116 colon, and HeLa cervical cancer cells (IC50s=0.3, 0.6, and 0.3 μM, respectively) and NIH373 fibroblasts (IC50=56.6 μM) but not MDA-MD-231 breast cancer cells (IC50=>100 μM). Collismycin A forms a complex with Fe(II) and Fe(III) at a 2:1 ratio, and the addition of iron ions inhibits the antiproliferative effect of collismycin A on HeLa cells, an effect that does not occur with the addition of zinc, manganese, copper, or magnesium ions.3 Collismycin A (1 μM) prevents apoptosis in the brain region of zebrafish larvae by 44% in a model of neuronal cell death induced by all-trans retinoic acid.
    Collismycin A

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