2. Metabolic Enzyme/Protease Anti-infection
  3. Drug Metabolite Antibiotic
  4. Desmethyl Levofloxacin

Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

For research use only. We do not sell to patients.

Desmethyl Levofloxacin Chemical Structure

Desmethyl Levofloxacin Chemical Structure

CAS No. : 117707-40-1

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Based on 1 publication(s) in Google Scholar

Other Forms of Desmethyl Levofloxacin:

Desmethyl Levofloxacin Related Antibodies

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Description

Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication[1].

IC50 & Target

Quinolone

 

Molecular Weight

347.34

Formula

C17H18FN3O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C(C1=O)=CN2[C@@H](C)COC3=C(N4CCNCC4)C(F)=CC1=C23)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 8.33 mg/mL (23.98 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8790 mL 14.3951 mL 28.7902 mL
5 mM 0.5758 mL 2.8790 mL 5.7580 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8790 mL 14.3951 mL 28.7902 mL 71.9756 mL
5 mM 0.5758 mL 2.8790 mL 5.7580 mL 14.3951 mL
10 mM 0.2879 mL 1.4395 mL 2.8790 mL 7.1976 mL
15 mM 0.1919 mL 0.9597 mL 1.9193 mL 4.7984 mL
20 mM 0.1440 mL 0.7198 mL 1.4395 mL 3.5988 mL
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Desmethyl Levofloxacin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Desmethyl Levofloxacin117707-40-1Drug MetaboliteAntibioticmetaboliteInhibitorinhibitorinhibit

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