Propionylmaridomycin

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Data Sheet Handling Instructions

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Propionylmaridomycin is a macrolide antibiotic with antibacterial activity. Propionylmaridomycin is rapidly absorbed from the gastrointestinal tract and rapidly distributed to tissues. Propionylmaridomycin radioactivity levels in the liver, kidneys, and lungs were significantly higher than in plasma, while distribution to the brain was less. Propionylmaridomycin is excreted primarily through the feces, and the high fecal recovery rate is due to unabsorbed compounds and biliary excretion of compounds and their metabolites. Propionylmaridomycin exhibits the highest antibacterial activity in the lungs. Propionylmaridomycin is completely converted to several metabolites in rats, of which 4''-depropionyl-9-propionylmaridomycin was identified as the major metabolite.

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Propionylmaridomycin Chemical Structure

CAS No. : 35775-65-6

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Description	Propionylmaridomycin is a macrolide antibiotic with antibacterial activity. Propionylmaridomycin is rapidly absorbed from the gastrointestinal tract and rapidly distributed to tissues. Propionylmaridomycin radioactivity levels in the liver, kidneys, and lungs were significantly higher than in plasma, while distribution to the brain was less. Propionylmaridomycin is excreted primarily through the feces, and the high fecal recovery rate is due to unabsorbed compounds and biliary excretion of compounds and their metabolites. Propionylmaridomycin exhibits the highest antibacterial activity in the lungs. Propionylmaridomycin is completely converted to several metabolites in rats, of which 4''-depropionyl-9-propionylmaridomycin was identified as the major metabolite^[1].
Molecular Weight	914.08
Formula	C₄₆H₇₅NO₁₇
CAS No.	35775-65-6
SMILES	C[C@H]1[C@@H]([C@@](O)(C[C@H](O[C@@H]2[C@@H](N(C)C)[C@@H]([C@@H](O[C@@H]3[C@@H]([C@@H](CC(O[C@@H](C[C@@H]4[C@@H](/C=C/[C@@H](OC(CC)=O)[C@@H](C[C@@H]3CC=O)C)O4)C)=O)OC(CC)=O)OC)O[C@@H]2C)O)O1)C)OC(CC(C)C)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (273 KB) Handling Instructions (2659 KB)
References	[1]. Studies on the absorption, distribution, metabolism, and excretion of propionylmaridomycin in rats [Content Brief]