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cytochrome bc1 complex

" in MedChemExpress (MCE) Product Catalog:

21

Inhibitors & Agonists

1

Recombinant Proteins

4

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-162066

    Parasite Infection
    DNDI-6174 is a cytochrome bc1 complex inhibitor with potent in vitro activity against a variety of Leishmania species. DNDI-6174 can reduce parasite burden in animal models of infection .
    DNDI-6174
  • HY-13832
    Atovaquone
    4 Publications Verification

    Atavaquone

    Parasite Cytochrome P450 Antibiotic Bacterial Infection Cancer
    Atovaquone (Atavaquone) is a potent, selective and orally active inhibitor of the parasite’s mitochondrial cytochrome bc1 complex. Atovaquone is against human and  P. falciparum cytochrome bc1 activity with IC50 values of 460 nM and 2.0 nM, respectively. Atovaquone is an antimalarial agent and has the potential for the investigation of neumocystis pneumonia, toxoplasmosis, malaria, and babesia .
    Atovaquone
  • HY-121214

    Mitochondrial Metabolism Infection
    Amisulbrom is a sulfonamide fungicide used to control oomycete diseases. Amisulbrom biochemically inhibits the cytochrome-bc1 complex of the mitochondrial electron transport system .
    Amisulbrom
  • HY-125776

    BAS 490 F

    Fungal Mitochondrial Metabolism Infection
    Kresoxim-methyl (BAS 490 F), a Strobilurin-based fungicide, inhibits the respiration at the complex III (cytochrome bc1 complex). Kresoxim-methyl binds to complex III from yeast with an apparent Kd of 0.07 μM proving a high affinity for this enzyme .
    Kresoxim-methyl
  • HY-W715444

    Antibiotic Fungal Mitochondrial Metabolism Infection
    Mucidin is an antifungal antibiotic that inhibits electron-transfer reactions in the cytochrome bc1 complex of the mitochondrial respiratory chain .
    Mucidin
  • HY-156137

    Biochemical Assay Reagents Others
    UHDBT is a cytochrome bc1 complex Qo site inhibitor. UHDBT can be used for electron transfer research .
    UHDBT
  • HY-13834

    Parasite Cytochrome P450 Infection
    GW844520 is an orally active inhibitor of cytochrome bc1 complex. GW844520 can be used in malaria and anti-plasmodium related research .
    GW844520
  • HY-13832S2

    Atavaquone-d5

    Isotope-Labeled Compounds Parasite Cytochrome P450 Antibiotic Infection
    Atovaquone-d5 is the deuterium labeled Atovaquone. Atovaquone (Atavaquone) is a potent, selective and orally active inhibitor of the parasite’s mitochondrial cytochrome bc1 complex. Atovaquone is against human and  P. falciparum cytochrome bc1 activity with IC50 values of 460 nM and 2.0 nM, respectively. Atovaquone is an antimalarial agent and has the potential for the investigation of neumocystis pneumonia, toxoplasmosis, malaria, and babesia[1][2].
    Atovaquone-d5
  • HY-13832S3

    cis-Atavaquone-d4

    Isotope-Labeled Compounds Parasite Cytochrome P450 Antibiotic Infection
    cis-Atovaquone-d4 is deuterium labeled Atovaquone. Atovaquone (Atavaquone) is a potent, selective and orally active inhibitor of the parasite’s mitochondrial cytochrome bc1 complex. Atovaquone is against human and  P. falciparum cytochrome bc1 activity with IC50 values of 460 nM and 2.0 nM, respectively. Atovaquone is an antimalarial agent and has the potential for the investigation of neumocystis pneumonia, toxoplasmosis, malaria, and babesia[1][2].
    cis-Atovaquone-d4
  • HY-13832R

    Parasite Cytochrome P450 Antibiotic Bacterial Infection Cancer
    Atovaquone (Standard) is the analytical standard of Atovaquone. This product is intended for research and analytical applications. Atovaquone (Atavaquone) is a potent, selective and orally active inhibitor of the parasite’s mitochondrial cytochrome bc1 complex. Atovaquone is against human and  P. falciparum cytochrome bc1 activity with IC50 values of 460 nM and 2.0 nM, respectively. Atovaquone is an antimalarial agent and has the potential for the investigation of neumocystis pneumonia, toxoplasmosis, malaria, and babesia .
    Atovaquone (Standard)
  • HY-13836

    Parasite Infection
    ELQ-300 is a potent and orally bioavailable antimalarial agent, acts as an inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (cyt bc1). ELQ-300 inhibits growth of P. falciparum Dd2, Tm90-C2B, and D1 with IC50 values of 6.6, 4.6 and 160 nM, respectively. ELQ-300 can be used for the research of antimalarial .
    ELQ-300
  • HY-121214R

    Mitochondrial Metabolism Infection
    Amisulbrom (Standard) is the analytical standard of Amisulbrom. This product is intended for research and analytical applications. Amisulbrom is a sulfonamide fungicide used to control oomycete diseases. Amisulbrom biochemically inhibits the cytochrome-bc1 complex of the mitochondrial electron transport system .
    Amisulbrom (Standard)
  • HY-121248

    AC217300

    Mitochondrial Metabolism Infection
    Hydramethylnon (AC217300) is an amidinohydrazone insecticide. Hydramethylnon's mechanism of action is through inhibition of mitochondrial respiration by inhibiting the electron transport chain at the cytochrome b-c1 complex. Hydramethylnon can be used to eliminate red imported fire ants, cockroaches, and other insects .
    Hydramethylnon
  • HY-125776R

    Fungal Mitochondrial Metabolism Infection
    Kresoxim-methyl (Standard) is the analytical standard of Kresoxim-methyl. This product is intended for research and analytical applications. Kresoxim-methyl (BAS 490 F), a Strobilurin-based fungicide, inhibits the respiration at the complex III (cytochrome bc1 complex). Kresoxim-methyl binds to complex III from yeast with an apparent Kd of 0.07 μM proving a high affinity for this enzyme .
    Kresoxim-methyl (Standard)
  • HY-B0849

    Fungal Reactive Oxygen Species Apoptosis Bacterial Phosphatase Infection
    Azoxystrobin is an orally active, broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis .
    Azoxystrobin
  • HY-B0849S

    Isotope-Labeled Compounds Fungal Reactive Oxygen Species Apoptosis Infection
    Azoxystrobin-d4 is deuterium labeled Azoxystrobin. Azoxystrobin is a broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis.
    Azoxystrobin-d4
  • HY-B0849S1

    Fungal Reactive Oxygen Species Apoptosis Infection
    Azoxystrobin-d3 is deuterium labeled Azoxystrobin. Azoxystrobin is a broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis[1].
    Azoxystrobin-d3
  • HY-B0849R

    Fungal Reactive Oxygen Species Apoptosis Infection
    Azoxystrobin (Standard) is the analytical standard of Azoxystrobin. This product is intended for research and analytical applications. Azoxystrobin is a broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis.
    Azoxystrobin (Standard)
  • HY-19877

    Parasite Infection
    GSK932121 is an antimalarial drug with activity that inhibits the electron transport chain of P. falciparum. GSK932121 acts selectively on this pathogen at the level of cytochrome bc1 (complex III). The synthesis method of GSK932121 is highly efficient, and the final structure can be obtained in only 5 steps. The synthesis of GSK932121 can be prepared atKilog scale to support clinical studies .
    GSK932121
  • HY-156136

    Biochemical Assay Reagents Others
    5-n-Heptyl-6-hydroxy-4,7-dioxobenzothiazole is a competitive Qo site inhibitor of the cytochrome bc 1 complex (cytochrome c oxidoreductase) from Saccharomyces cerevisiae .
    5-n-Heptyl-6-hydroxy-4,7-dioxobenzothiazole
  • HY-151556

    Fungal Infection
    Antifungal agent 45 is with fungicidal activities. Antifungal agent 45 shows excellent characteristics superior to Kresoxim-methyl (HY-125776), in which the activity enhancement against Phytophthora capsici was the most remarkable, with an EC50 value of about 5 μM .
    Antifungal agent 45

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