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Results for "

fluorogenic peptide substrate

" in MedChemExpress (MCE) Product Catalog:

17

Inhibitors & Agonists

4

Fluorescent Dye

17

Peptides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-155667A
    Z-Nle-Lys-Arg-AMC acetate

    		Cathepsin Others
    Z-Nle-Lys-Arg-AMC acetate is a fluorogenic peptide substrate that specifically monitors cathepsin B activity over a broad pH range .
    Z-Nle-Lys-Arg-AMC acetate
  • HY-P2295
    Dabcyl-KTSAVLQSGFRKME-Edans TFA
    1 Publications Verification

    		 SARS-CoV Others
    Dabcyl-KTSAVLQSGFRKME-Edans TFA is a fluorogenic peptide. Dabcyl-KTSAVLQSGFRKME-Edans TFA is used as the substrate to measure the enzymatic activities of protease forms. Dabcyl-KTSAVLQSGFRKME-Edans TFA has the potential for study 2019-nCoV (COVID-19) infection .
    Dabcyl-KTSAVLQSGFRKME-Edans TFA
  • HY-P1448
    Ac-Leu-Arg-AMC

    		Fluorescent Dye Neurological Disease
    Ac-Leu-Arg-AMC is a fluorogenic peptide substrate.
    Ac-Leu-Arg-AMC
  • HY-P2008
    Boc-Ile-Glu-Gly-Arg-AMC
    1 Publications Verification

    IEGR-AMC

    		 Factor Xa Cardiovascular Disease
    Boc-Ile-Glu-Gly-Arg-AMC (IEGR-AMC) is an activated factor X (FXa) specific fluorogenic peptide substrate used for Factor VIII determination .
    Boc-Ile-Glu-Gly-Arg-AMC
  • HY-P10163
    α-Secretase Substrate II, Fluorogenic

    		Fluorescent Dye Others
    α-Secretase Substrate II, Fluorogenic is an internally quenched fluorogenic peptide substrate for α-Secretase that contains the α-secretase cleavage site of β-Amyloid precursor protein (APP) .Ex/Em = 340/490 nm
    α-Secretase Substrate II, Fluorogenic
  • HY-P4334
    Bz-RGFFL-4MβNA

    Bz-Arg-Gly-Phe-Phe-Leu-4MβNA

    		 Fluorescent Dye Others
    Bz-RGFFL-4MβNA (Bz-Arg-Gly-Phe-Phe-Leu-4MβNA) is a peptide and can be used fluorogenic substrate .
    Bz-RGFFL-4MβNA
  • HY-155667
    Z-Nle-Lys-Arg-AMC

    		Others Others
    Z-Nle-Lys-Arg-AMC is a fluorogenic peptide substrate that specifically monitors cathepsin B activity over a broad pH range .
    Z-Nle-Lys-Arg-AMC
  • HY-P10008
    Cathepsin D/E Substrate, Fluorogenic

    		Cathepsin Cancer
    Cathepsin D/E Substrate, Fluorogenic, 11 amino acid peptide, is a selective substrate for cathepsins D and E. Cathepsin D/E Substrate, Fluorogenic does not act as a substrate for cathepsins B, H, or L .
    Cathepsin D/E Substrate, Fluorogenic
  • HY-P4366
    Tos-Gly-Pro-Lys-AMC

    		Ser/Thr Protease Others
    Tos-Gly-Pro-Lys-AMC is a fluorogenic peptide substrate of tryptase .
    Tos-Gly-Pro-Lys-AMC
  • HY-P5354
    FRETS-VWF73

    		Fluorescent Dye Others
    FRETS-VWF73, a 73-amino-acid peptide, is a fluorogenic substrate for ADAMTS13 assay (Ex=340 nm; Em=450 nm). .
    FRETS-VWF73
  • HY-120659
    Gly-Gly-AMC

    		Fluorescent Dye Others
    Gly-Gly-AMC is a fluorogenic peptide substrate. Gly-Gly-AMC can be used to assess bacterial protease activity of P. aeruginosa and S. aureus .
    Gly-Gly-AMC
  • HY-D1705
    Ac-ANW-AMC

    		Proteasome Inflammation/Immunology
    Ac-ANW-AMC is a fluorogenic substrate for immunoproteasome. Ac-ANW-AMC can be used to measure β5i activity (Ex=345 nm, Em=445 nm) .
    Ac-ANW-AMC
  • HY-P2536
    Mca-Ala-Pro-Lys(Dnp)-OH

    		Angiotensin-converting Enzyme (ACE) Others
    Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung .
    Mca-Ala-Pro-Lys(Dnp)-OH
  • HY-P1986
    Z-DEVD-AFC

    		Caspase Cancer
    Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity .
    Z-DEVD-AFC
  • HY-P4403
    Z-DEVD-R110

    (Z-Asp-Glu-Val-Asp)₂-Rhodamine 110

    		 Fluorescent Dye Apoptosis Caspase Others
    Z-DEVD-R110 ((Z-Asp-Glu-Val-Asp)2-Rhodamine 110) is a fluorogenic caspase-3/7 substrate. Z-DEVD-R110 can be used to detect apoptosis. Z-DEVD-R110 is a rhodamine derivative with two four–amino acid (DEVD) peptides linked to the fuorophore .
    Z-DEVD-R110
  • HY-P5272
    Histatin-3 TFA

    		Bacterial Inflammation/Immunology
    Histatin-3 TFA, a 32 amino acid peptide, possesses powerful antimicrobial properties. Histatin-3 TFA behaves as a substrate for proprotein convertase 1 (PC1), being cleaved by this endoprotease primarily at a site carboxy terminal to the single Arg25 residue (HRGYR decrease SN). Histatin-3 TFA is a moderately potent, reversible and competitive inhibitor of the furin-mediated cleavage of the pentapeptide pGlu-Arg-Thr-Lys-Arg-MCA fluorogenic substrate, with an estimated inhibition constant Ki of 1.98 μM .
    Histatin-3 TFA
  • HY-P5380
    TNO211

    Dabcyl-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2

    		 MMP Others
    TNO211 is a biological active peptide. (Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.This peptide is a highly soluble fluorogenic MMP substrate for MMP-2, 8, 12, 13 and 14, containing the MMP cleavable Gly-Leu bond and EDANS/DABCYL. Fluorogenic assays using TNO211 are sensitive and can detect MMP activity in culture medium from endothelial cells and untreated synovial fluid from patients. Abs/Em = 340/490 nm.)
    TNO211

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