2. Metabolic Enzyme/Protease
  3. Cathepsin
  4. Z-Nle-Lys-Arg-AMC acetate

Z-Nle-Lys-Arg-AMC acetate is a fluorogenic peptide substrate that specifically monitors cathepsin B activity over a broad pH range.

For research use only. We do not sell to patients.

Z-Nle-Lys-Arg-AMC acetate Chemical Structure

Z-Nle-Lys-Arg-AMC acetate Chemical Structure

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5 mg USD 140 In-stock
10 mg USD 220 In-stock
25 mg USD 420 In-stock
50 mg USD 650 In-stock
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Other Forms of Z-Nle-Lys-Arg-AMC acetate:

Z-Nle-Lys-Arg-AMC acetate Related Antibodies

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Cathepsin B Cathepsin C Cathepsin D Cathepsin E Cathepsin K Cathepsin L Cathepsin S

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Description

Z-Nle-Lys-Arg-AMC acetate is a fluorogenic peptide substrate that specifically monitors cathepsin B activity over a broad pH range[1].

Molecular Weight

706.83 (free base)

Formula

C36H50N8O7.xC2H4O2
Appearance

Solid

Color

White to off-white

SMILES

CCCC[C@@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(NC1=CC(O2)=C(C=C1)C(C)=CC2=O)=O)=O)CCCCN)=O)NC(OCC3=CC=CC=C3)=O.CC(O)=O.[x]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL

*"≥" means soluble, but saturation unknown.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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C2

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V2

In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References
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Z-Nle-Lys-Arg-AMC acetate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Z-Nle-Lys-Arg-AMCCathepsincathepsin BfluorogenicpeptidesubstrateInhibitorinhibitorinhibit

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Product Name:
Z-Nle-Lys-Arg-AMC acetate
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HY-155667A
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