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Results for "

furin

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

6

Peptides

2

Recombinant Proteins

1

Antibodies

1

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P1028
    Hexa-D-arginine
    3 Publications Verification

    furin Inhibitor II

    		 Bacterial Infection
    Hexa-D-arginine (Furin Inhibitor II) is a stable furin inhibitor with Ki values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo .
    Hexa-D-arginine
  • HY-110147B
    SSM3 tetraTFA hydrate

    		Furin Infection
    SSM3 tetraTFA hydrate is a potent synthetic furin inhibitor with an EC50 and a Ki of 54 nM and 12 nM, respectively. SSM3 tetraTFA hydrate is able to block furin-dependent cell surface processing of anthrax protective antigen-83 in vitro .
    SSM3 tetraTFA hydrate
  • HY-147140
    BOS-318

    		Furin Inflammation/Immunology
    BOS-318 is a potent, slowly dissociating, highly selective, and cell-permeable furin inhibitor with IC50 value of 1.9 nM. BOS-318 protects ENaC from subsequent activation by neutrophil elastase. BOS-318 can be used for the rsearch for CF lung disease .
    BOS-318
  • HY-P5272
    Histatin-3 TFA

    		Bacterial Inflammation/Immunology
    Histatin-3 TFA, a 32 amino acid peptide, possesses powerful antimicrobial properties. Histatin-3 TFA behaves as a substrate for proprotein convertase 1 (PC1), being cleaved by this endoprotease primarily at a site carboxy terminal to the single Arg25 residue (HRGYR decrease SN). Histatin-3 TFA is a moderately potent, reversible and competitive inhibitor of the furin-mediated cleavage of the pentapeptide pGlu-Arg-Thr-Lys-Arg-MCA fluorogenic substrate, with an estimated inhibition constant Ki of 1.98 μM .
    Histatin-3 TFA
  • HY-P1028A
    Hexa-D-arginine TFA

    furin Inhibitor II TFA

    		 Bacterial Infection
    Hexa-D-arginine TFA (Furin Inhibitor II TFA) is a stable furin inhibitor with Ki values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine TFA blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo .
    Hexa-D-arginine TFA
  • HY-P3797
    Furin Substrate

    		Furin Cancer
    Furin Substrate is an peptide. Furin Substrate can be used for the research of various biochemical .
    Furin Substrate
  • HY-163738
    Furin-IN-2

    		Furin SARS-CoV Infection
    Furin-IN-2 (compound P3) is a potent inhibitor of furin, with the IC50 of 35 μM. Furin-IN-2 shows antiviral activity .
    Furin-IN-2
  • HY-RS05148
    FURIN Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    FURIN Human Pre-designed siRNA Set A contains three designed siRNAs for FURIN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    FURIN Human Pre-designed siRNA Set A
    FURIN Human Pre-designed siRNA Set A
  • HY-110147A
    SSM3 tetraTFA

    		Furin Infection
    SSM3 tetraTFA is a potent synthetic furin inhibitor with an EC50 and a Ki of 54 nM and 12 nM, respectively. SSM3 tetraTFA is able to block furin-dependent cell surface processing of anthrax protective antigen-83 in vitro .
    SSM3 tetraTFA
  • HY-150737
    MI-1851

    		SARS-CoV Infection
    MI-1851 is a potent furin inhibitor. MI-1851 prevents the proteolytic processing of the S protein of SARS-CoV-2 by endogenous flavoprotease in HEK293 cells. MI-185 has antiviral activity .
    MI-1851
  • HY-P4548
    Boc-Arg-Val-Arg-Arg-AMC hydrochloride

    Boc-RVRR-AMC

    		 Furin Others
    Boc-Arg-Val-Arg-Arg-AMC hydrochloride (Boc-RVRR-AMC) is a synthetic fluorogenic substrate that is efficiently cleaved by furin .
    Boc-Arg-Val-Arg-Arg-AMC hydrochloride
  • HY-P10150
    IN-2-LF

    		Bacterial Infection
    IN-2-LF is an inhibitor of lethal factor. IN-2-LF also inhibits furin with an IC50 of 2 μM. IN-2-LF enhances protection against anthrax lethal toxin when in combination with D6R .
    IN-2-LF

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