2. Metabolic Enzyme/Protease
  3. Furin
  4. Boc-Arg-Val-Arg-Arg-AMC hydrochloride

Boc-Arg-Val-Arg-Arg-AMC hydrochloride  (Synonyms: Boc-RVRR-AMC)

Cat. No.: HY-P4548 Purity: 99.18%
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Boc-Arg-Val-Arg-Arg-AMC hydrochloride (Boc-RVRR-AMC) is a synthetic fluorogenic substrate that is efficiently cleaved by furin.

For research use only. We do not sell to patients.

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Boc-Arg-Val-Arg-Arg-AMC hydrochloride Chemical Structure

Boc-Arg-Val-Arg-Arg-AMC hydrochloride Chemical Structure

CAS No. : 136132-77-9

Size Price Stock Quantity
5 mg USD 210 In-stock
10 mg USD 340 In-stock
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100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Boc-Arg-Val-Arg-Arg-AMC hydrochloride Related Antibodies

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Description

Boc-Arg-Val-Arg-Arg-AMC hydrochloride (Boc-RVRR-AMC) is a synthetic fluorogenic substrate that is efficiently cleaved by furin[1].

Molecular Weight

879.45

Formula

C38H63ClN14O8
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

{Boc-Arg}-Val-Arg-{Arg-AMC}
Sequence Shortening

{Boc-Arg}-VR-{Arg-AMC}
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (113.71 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1371 mL 5.6854 mL 11.3707 mL
5 mM 0.2274 mL 1.1371 mL 2.2741 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.1371 mL 5.6854 mL 11.3707 mL 28.4269 mL
5 mM 0.2274 mL 1.1371 mL 2.2741 mL 5.6854 mL
10 mM 0.1137 mL 0.5685 mL 1.1371 mL 2.8427 mL
15 mM 0.0758 mL 0.3790 mL 0.7580 mL 1.8951 mL
20 mM 0.0569 mL 0.2843 mL 0.5685 mL 1.4213 mL
25 mM 0.0455 mL 0.2274 mL 0.4548 mL 1.1371 mL
30 mM 0.0379 mL 0.1895 mL 0.3790 mL 0.9476 mL
40 mM 0.0284 mL 0.1421 mL 0.2843 mL 0.7107 mL
50 mM 0.0227 mL 0.1137 mL 0.2274 mL 0.5685 mL
60 mM 0.0190 mL 0.0948 mL 0.1895 mL 0.4738 mL
80 mM 0.0142 mL 0.0711 mL 0.1421 mL 0.3553 mL
100 mM 0.0114 mL 0.0569 mL 0.1137 mL 0.2843 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Boc-Arg-Val-Arg-Arg-AMC hydrochloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Boc-Arg-Val-Arg-Arg-AMC136132-77-9Boc-RVRR-AMCFurinInhibitorinhibitorinhibit

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