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Results for "

haptens

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Biochemical Assay Reagents (15) Endogenous Metabolite (1) Fluorescent Dye (1) Fungal (3) GABA Receptor (1) Integrin (1) Isotope-Labeled Compounds (1)
By Research Areas:	Cancer (16) Infection (7) Inflammation/Immunology (64) Metabolic Disease (2) Neurological Disease (7)
Click Chemistry:	DBCO (1) Azide (1)

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Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W008234

N-Phthaloyl-β-alanine	Others	Inflammation/Immunology
N-Phthaloyl-β-alanine (hapten FP) is an FX-type hapten without CH2S moiety. N-Phthaloyl-β-alanine can be coupled to OVA using the mixed anhydride method. N-Phthaloyl-β-alanine has more heterologies .

HY-155455

Dicamba-(CH2)5-acid	Others	Inflammation/Immunology
Hapten Dca is an immunizing hapten. Hapten Dca is activated by a solution of N, N′-disuccinimidyl carbonate. Hapten Dca with a carboxyl functional group is conjugated to proteins .

HY-155454

TATP-C4-acid	Others	Inflammation/Immunology
TATP hapten is a *hapten* made from acetone, hydrogen peroxide, and 7-oxo octanoic acid. TATP hapten coupled with bovine serum albumin can raise an immune response against TATP. TATP hapten can coupled directly to BSA and HRP via N-hydroxysuccinimide chemistry to produce haptenated proteins .

HY-W038001

DOTA-benzene	Others	Cancer
DOTA-benzene is a DOTA-based small molecule hapten. DOTA-biotin has been used extensively as a hapten for PRIT .

HY-157224

Zearalanone carboxymethoxyl oxime	Others	Others
Zearalanone carboxymethoxyl oxime is a hapten that binds to the free amine on BSA .

HY-155451

GK83	Others	Neurological Disease
GK83 is a carboxyl nicotine hapten that can be used in the study of nicotine dependence .

HY-155449

GK60	Others	Neurological Disease
GK60 is a carboxyl nicotine hapten that can be used in the study of nicotine dependence .

HY-155445

di-DTPA TL	Others	Cancer
di-DTPA TL is a hydrophilic bivalent DTPA hapten that can be used for tumor research .

HY-W014665

N-Phthaloylglycine Phthaloyl glycine	Others	Cancer
N-Phthaloylglycine (Phthaloyl glycine) is an FX-type hapten that attaches to free amine groups of proteins .

HY-163026

Cyromazine-3-mercaptopropanoic acid	Others	Others
Cyromazine-3-mercaptopropanoic acid (Compound 7) is a hapten conjugated to BSA and OVA for immunoassays of triazine herbicides .

HY-157187

Fenhexamid-1-pentanoic acid	Others	Others
Fenhexamid-1-pentanoic acid is a hapten that can be covalently coupled to a carrier protein for the determination of cyclohexamide residues .

HY-163037

Pseudo-β-D-mannopyranose	Others	Inflammation/Immunology
Pseudo-β-D-mannopyranose is a hapten that can be coupled with mannose .

HY-157173

Mannosamine-biotin adduct	Others	Inflammation/Immunology
Mannosamine–biotin adduct is a hapten. Mannosamine–biotin adduct conjugated to hsIgG significantly reduces antibody immune responses against hsIgG .

HY-155468

AG8.0	Others	Others
AG8.0 is a symmetric di-HSG bivalent hapten. AG8.0 is stable in vivo for 24 h .

HY-155450

GK81	Others	Neurological Disease
GK81 is a nicotine *hapten*. GK81 contains a linker attached to the 6-position of nicotine. GK81 conjugates to KLH via carbodiimide-mediated reactions .

HY-155498

TETS-4-Methylaniline	GABA Receptor	Neurological Disease
TETS-4-Methylaniline (compound 2k) is a hapten. TETS-4-Methylaniline conjugates to the carrier protein via using either diazotization or glutaraldehyde methods .

HY-149744

FXb	Others	Inflammation/Immunology
FXb is an immunizing and functionalized *hapten* and can be used for protein bioconjugates preparation .

HY-155453

IB87	Others	Others
IB87 is an amine nicotine hapten. IB87 contains a linker e attached to the 6-position of (S)-enantiomer of nicotine. IB87 conjugates to KLH via carbodiimide-mediated reactions .

HY-155442

MIQ-N-succinate	Others	Inflammation/Immunology
MIQ-N-succinate is a hapten with a four-carbon chain. MIQ-N-succinate consist of MIQ and succinic anhydride. MIQ-N-succinate has a carboxylic acid end group to attach to the lysine residues on the carrier proteins .

HY-149737

FXn	Others	Others
FXn is a hapten that can be used for the generation of mAbs. FXh is activated by incubation with N, N′-disuccinimidyl carbonate, and Et3N in acetonitrile at 0 °C. FXn is covalently linked to the protein via N-hydroxy succinimidyl ester .

HY-149738

FXh	Others	Others
FXh is a functionalized hapten activated by incubation with N, N′-disuccinimidyl carbonate, and Et3N in acetonitrile at 0 °C. FXh can improve the affinity of antigens .

HY-157205

Zeph	Others	Inflammation/Immunology
Zeph is a small chemical group double heterologous *hapten* of Zep and combines with a specific antibody but lacks antigenicity of its own.

HY-161006

(S)-TETS-C4-acid	Others	Inflammation/Immunology
(S)-TETS-C4-acid (Compound 2d) is a hapten coupled directly to a carrier protein through a carboxylic acid functionality. (S)-TETS-C4-acid (Compound 2d) can be used to detect tetramethylenedisulfotetramine (TETS) .

HY-157191

Fenhexamid-5-hexenoic acid	Others	Others
Fenhexamid-5-hexenoic acidis a hapten that can be coupled with fenhexamid .

HY-163021

Simeton-acetic acid	Others	Inflammation/Immunology
Simeton-acetic acid is an immunizing hapten that can be coupled with bovine serum albumin. Simeton-acetic acid-BSA can produce PcAbs obtained with titer 1.0×10 ³ .

HY-157218

PPm	Fungal	Inflammation/Immunology
PPm, a derivative of penthiopyrad and hapten, is a representative member of the succinate dehydrogenase inhibitors group of fungicides .

HY-155495

(±)-Bupropion-(CH2)3-OH hydrochloride	Others	Inflammation/Immunology
(±)-Bupropion-(CH2)3-OH hydrochloride (compound 3) is a hapten useful in the radioimmunoassay of Bupropion (HY-B0403) .

HY-149753

Methylthiomcresol-succinaldehydic acid	Others	Inflammation/Immunology
Methylthiomcresol-succinaldehydic acid is a fenthion hapten that can be used for immunoreagent production (protein conjugates and polyclonal antibodies) .

HY-157192

Clothianidin-2-S-propanoic acid	Others	Infection
Clothianidin-2-S-propanoic acid is a clothianidin hapten. Clothianidin-2-S-propanoic can be used for the research of insecticide .

HY-124004

Acetyl-6-formylpterin Ac-6-FP	Others	Inflammation/Immunology
Acetyl-6-formylpterin (Ac-6-FP) is a hapten that covalently binds to MR1 through residue Lys43 of the protein, resulting in protein upregulation. Acetyl-6-formylpterin (Ac-6-FP) can be used in the study of inflammation .

HY-163039

DOTA-biotin	Others	Inflammation/Immunology
DOTA-biotin is a DOTA-based small molecule hapten. DOTA-biotin has low tissue and whole-body retention in mice 4 h postinjection .

HY-163020

Ametryn-acetic acid	Others	Cancer
Ametryn-acetic acid is a hapten that can be coupled with bovine serum albumin (BSA). PcAbs obtained were with a high titer (at least 6.4×10 ⁴) .

HY-155447

AG3.0	Others	Cancer
AG3.0 is a symmetric di-HSG bivalent hapten. AG3.0 can be used for the research of pretargeted radioimmunotherapy .

HY-157190

Fenhexamid-butyric acid	Others	Inflammation/Immunology
Fenhexamid-butyric acid (Compound FHo) is a hapten designed based on fenhexamid, which can produce monoclonal antibodies with an IC₅₀ value of 0.66-0.93 nM .

HY-157185

Etioporphyrin IV acid	Others	Others
Etioporphyrin IV acid is a hapten that can be coupled with bovine serum albumin and keyhole limpet hemocyanin. Etioporphyrin IV acid can target porphyrin with IC₅₀ of 1.3 μM .

HY-163011

Dicamba-hex-5-ynoic acid	Others	Others
Dicamba-hex-5-ynoic acid is a hapten that can be coupled with Ovalbumin (OVA). Dicamba-hex-5-ynoic acid can be used in dicamba analysis .

HY-155448

GK56	Others	Neurological Disease
GK56 is a carboxyl nicotine *hapten*, which contains a linker attached to the 6-position of nicotine. GK56 conjugates to KLH via carbodiimide-mediated reactions .

HY-163040

DOTA-Tyr-Lys-DOTA	Others	Inflammation/Immunology
DOTA-Tyr-Lys-DOTA is a DOTA-based small molecule hapten. DOTA-Tyr-Lys-DOTAexhibits rapid clearance and low whole-body retention. DOTA-Tyr-Lys-DOTA can used in study pretargeted radioimmunotherapy .

HY-161001

AMOZ-CHPh-3-acid	Others	Others
AMOZ-CHPh-3-acid is hapten against furaltadone metabolite AMOZ. AMOZ-CHPh-3-acid can couple to BSA for immunogens and couple to OVA for coating antigen .

HY-157203

Cholic acid-cysteine-cyanuric chloride complex	Others	Others
Cholic acid-cysteine-cyanuric chloride complex is a hapten linker molecule comprising of the antigen, cholic acid and the reactive group for covalent attachment, cyanuric chloride .

HY-155471

IMP 245	Others	Others
IMP 245 is a symmetric di-HSG bivalent hapten. IMP 245 has low toxicity, high affinity binding to available antibodies and absence of cross reactivity or non-specific binding with body components .

HY-163057

2,2',2''-Nitrilotris(NH-EG8-Lys-2,4-dinitroaniline)	Others	Inflammation/Immunology
2,2',2''-Nitrilotris(NH-EG8-Lys-2,4-dinitroaniline) is a trivalent hapten. 2,2',2''-Nitrilotris(NH-EG8-Lys-2,4-dinitroaniline) can aggregate with monoclonal anti-2,4-DNP IgG (IgGDNP) .

HY-157200

2,4-DA-6-FP	Others	Inflammation/Immunology
2,4-DA-6-FP is a hapten and MR1 ligand. 2,4-DA-6-FP can used in study autoimmune diseases and cancers .

HY-78961

6-Maleimidohexanoic acid N-hydroxysuccinimide ester EMCS	ADC Linker	Cancer
6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) is a heterobifunctional cross-linking reagent. EMCS is used as a unique and useful reagent for preparation of hapten conjugate and enzyme immunoconjugates .

HY-157269

J10-1	Others	Inflammation/Immunology
J10-1 is a hapten. J10-1 promotes peptide exchange of all DR alleles (DR1, DR2, DR4 (DRB1*0401)) and promotes peptide binding to MHC II, which can be used in the study of immune regulation .

HY-161004

AMOZ-CH-acid	Others	Inflammation/Immunology
AMOZ-CH-acid (Hapten 5) is an immunizing and heterologous hapten. AMOZ-CH-acid and ovalbumin conjugate is a coating antigen that improves assay sensitivity .

HY-161003

AMOZ-CHPh-3-O-C-acid	Others	Cancer
AMOZ-CHPh-3-O-acid (hapten 4) is an immunizing hapten, coupled to BSA for immunogens and coupled to OVA for coating antigens .

HY-108026

Hapten C	Biochemical Assay Reagents	Others
Hapten C is a derivative of histamine. Hapten C is utilized for synthesis of immunogens and coating antigens, that can quantitative determine the histamine via ELISA .

HY-157259

Trimethoprim propanoic acid	Others	Others
Trimethoprim propanoic acid is a *hapten*.

HY-149748

(5α)-Pregnan-20-one-succinic	Others	Others
2DBL is a hapten .

Cat. No.	Product Name

HY-L076

Drug-Induced Liver Injury (DILI) Compound Library

1,434 compounds

Drug-induced liver injury (DILI; also known as drug-induced hepatotoxicity) is caused by medications (prescription or OTC), herbal and dietary supplements (HDS), or other xenobiotics that result in abnormalities in liver tests or in hepatic dysfunction that cannot be explained by other causes. Drugs are an important cause of liver injury. Drug-induced hepatic injury is the most common reason cited for withdrawal of an approved drug.

DILI is thought to occur via several different mechanisms. Among these are direct impairment of the structural (e.g., mitochondrial dysfunction) and functional integrity of the liver; production of a metabolite that alters hepatocellular structure and function; production of a reactive drug metabolite that binds to hepatic proteins to produce new antigenic drug-protein adducts, which are targeted by hosts’ defenses (the hapten hypothesis); and initiation of a systemic hypersensitivity response (i.e., drug allergy) that damages the liver.

MCE Drug-induced Liver Injury (DILI) Compound Library contains a unique collection of 1,434 hepatotoxicity causing compounds and is a powerful tool to research DILI and other drug toxicities. This library can be used to understand the mechanisms of DILI, identify biomarkers for early DILI prediction, and allow timely recognition during drug development, thus finally achieving successful DILI prevention and assessment in the pre-marketing phase.

Cat. No.	Product Name	Type

HY-66019

FITC

40+ Cited Publications

Fluorescein 5-isothiocyanate

Fluorescent Dyes/Probes

FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .

Cat. No.	Product Name	Type

HY-NP133

NP-KLH 4-Hydroxy-3-nitrophenylacetyl-Keyhole Limpet Hemocyanin	Native Proteins
NP-KLH is a 4-Hydroxy-3-nitrophenylacetyl (NP) hapten. NP-KLH can be used for study as a carrier protein in immunological research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7575

Lacto-N-fucopentaose II LNFP II	Structural Classification Polysaccharides Classification of Application Fields Source classification Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides Cancer	Endogenous Metabolite
Lacto-N-fucopentaose II (LNFP II) is a sialyl-Lewis, hapten of human Lewis bloodgroup determinant. Lacto-N-fucopentaose II monosialo-ganglioside/glycolipid and sialyl derivative, CA 19-9, is a molecular tumour markers (TM) for biliopancreatic malignancy .

Cat. No.	Product Name	Chemical Structure

HY-N8573S

β-Phellandrene-d2
β-Phellandrene-d₂ is deuterated labeled Methyl 2-Octynoate (HY-W013576). Methyl 2-Octynoate is a hapten .

Cat. No.	Product Name		Classification

HY-163045

4-Azidophenylarsonic acid		Azide
4-Azidophenylarsonic acid, a Hapten that contains a diazonium group, is a probes of antibody response and immunorecognition .

HY-157182

DNP-PEG2-NHCO-C2-DBCO		DBCO
DNP-PEG2-NHCO-C2-DBCO is a clickable hapten that bears a dinitrophenyl (DNP) moiety as the antibody‐recruiting motif at one end, a polyethylene glycol chain as a spacer and a dibenzocyclooctene at the other end for the SPAAC chemistry .

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