2. Click Chemistry
  3. DBCO

DBCO

DBCO (200):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-42973
    DBCO-NHS ester 1353016-71-3 99.53%
    DBCO-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-NHS ester
  • HY-140272
    DBCO-PEG4-NHS ester 1427004-19-0 98.66%
    DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG4-NHS ester
  • HY-W000423
    DBCO-amine 1255942-06-3 99.11%
    DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-amine
  • HY-136314
    DBCO-PEG4-VC-PAB-MMAE 2129164-91-4 99.88%
    DBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE (HY-15162). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. DBCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG4-VC-PAB-MMAE
  • HY-42972
    DBCO-acid 1353016-70-2 99.63%
    DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-acid
  • HY-D2171A
    AF488 DBCO ditriethylamine
    AF488 DBCO ditriethylamine is the ditriethylamine salt form of AF488 DBCO (HY-D2171). AF488 DBCO ditriethylamine is a fluorescent dye that labels azide-containing biomolecules. DBCO is the bioorthogonal partner of azide that allows covalent coupling in the absence of copper. AF488 is a bright, photostable green fluorophore. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively.
    AF488 DBCO ditriethylamine
  • HY-164792
    DBCO-PEG3-VC-Exatecan 2754384-70-6
    DBCO-PEG3-VC-Exatecan (compound 25) is a Drug-Linker Conjugate for ADC. DBCO-PEG3-VC-Exatecan contains the ADC linker (DBCO-PEG3-VC) and a DNA topoisomerase I inhibitor Exatecan (HY-13631).
    DBCO-PEG3-VC-Exatecan
  • HY-159529
    DBCO-PEG4-Eosin 5-isothiocyanate
    DBCO-PEG4-Eosin 5-isothiocyanate is a fluorescent probe. DBCO-PEG4-Eosin 5-isothiocyanate contains a clickable functional group, DBCO, and four PEG units. DBCO-PEG4-Eosin 5-isothiocyanate can be used for various imaging detections.
    DBCO-PEG4-Eosin 5-isothiocyanate
  • HY-134723
    DBCO-PEG4-GGFG-Dxd 2694856-51-2 98.42%
    DBCO-PEG4-GGFG-Dxd is a agent-linker conjugate for ADC with potent antitumor activity by using Dxd (a DNA topoisomerase I inhibitor), linked via the cleavable ADC linker DBCO-PEG4-GGFG. DBCO-PEG4-GGFG-Dxd is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG4-GGFG-Dxd
  • HY-130809
    DBCO-PEG4-Biotin 1255942-07-4 98.62%
    DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 4 PEGs. DBCO-PEG4-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction. DBCO-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG4-Biotin
  • HY-148476
    Tri-GalNAc-DBCO 99.92%
    Tri-GalNAc-DBCO can bind to the desialic acid glycoprotein receptor (ASGPR) to drive protein downregulation and target protein degradation, where GalNAc is a high-affinity ligand for hepatocyte-specific ASGPR. Tri-GalNAc-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    Tri-GalNAc-DBCO
  • HY-126885
    DBCO-PEG5-NHS ester 2144395-59-3
    DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG5-NHS ester
  • HY-D1069
    DBCO-Cy3 1782950-79-1 98.00%
    DBCO-Cy3 (DBCO-Sulfo-Cy3) is the derivative of Cyanine3 fluorophore, a pH insensitive from pH (4-10) orange fluorescent dyewith excitation maximum 555 nm and emission maximum of 580nm. DBCO-Cy3 has fast reaction kinetics and good stability, and is productive to use in many standard fluorescent instrumentations. DBCO-Cy3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-Cy3
  • HY-130990
    DBCO-PEG4-Val-Cit-PAB-MMAF 2244602-23-9 99.99%
    DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-Val-Cit-PAB-MMAF is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG4-Val-Cit-PAB-MMAF
  • HY-126690
    DBCO-(PEG2-VC-PAB-MMAE)2 2259318-55-1 99.21%
    DBCO-(PEG2-VC-PAB-MMAE)2 is made by MMAE conjugated to the cleavable DBCO-(PEG2-VC-PAB)2 linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody agent conjugate. DBCO-(PEG2-VC-PAB-MMAE)2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-(PEG2-VC-PAB-MMAE)2
  • HY-D1068
    Cy5-DBCO 1564286-24-3 99.86%
    Cy5-DBCO (DBCO-Sulfo-Cy5) is a near-infrared (NIR)red fluorescent dye with λabsand λem of 646nm and 670 nm, respectively. Cy5-DBCO (DBCO-Sulfo-Cy5) is not suitable for staining intracellular components of permeabilezed cell, it may exhibits a high background. Cy5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    Cy5-DBCO
  • HY-115524
    DBCO-NHS ester 2 1384870-47-6 99.69%
    DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry. DBCO-NHS ester 2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-NHS ester 2
  • HY-133433
    DBCO-PEG4-VA-PBD 2241644-09-5 99.68%
    DBCO-PEG4-VA-PBD is a agent-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via DBCO-PEG4-VA. DBCO-PEG4-VA-PBD is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG4-VA-PBD
  • HY-140274
    DBCO-PEG12-NHS ester 2093934-94-0 ≥99.0%
    DBCO-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DBCO-PEG12-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG12-NHS ester
  • HY-123916
    DBCO-Biotin 1418217-95-4 98.49%
    DBCO-Biotin is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. DBCO-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-Biotin