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  4. Sulfamethoxazole-NO

Sulfamethoxazole-NO (SMX-NO) is the major immunogen in sulfonamide allergy, producing modest ascorbic acid depletion and hemoglobin adduct formation. Sulfamethoxazole-NO haptens tissue proteins and is immunogenic in rodents.

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Sulfamethoxazole-NO Chemical Structure

Sulfamethoxazole-NO Chemical Structure

CAS No. : 29699-89-6

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25 mg USD 304 In-stock
50 mg USD 487 In-stock
100 mg USD 780 In-stock
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Other Forms of Sulfamethoxazole-NO:

Sulfamethoxazole-NO Related Antibodies

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Description

Sulfamethoxazole-NO (SMX-NO) is the major immunogen in sulfonamide allergy, producing modest ascorbic acid depletion and hemoglobin adduct formation. Sulfamethoxazole-NO haptens tissue proteins and is immunogenic in rodents[1].

Molecular Weight

283.26

Formula

C10H9N3O5S
CAS No.
Appearance

Solid

SMILES

O=S(C1=CC=C([N+]([O-])=O)C=C1)(NC2=NOC(C)=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (353.03 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5303 mL 17.6516 mL 35.3033 mL
5 mM 0.7061 mL 3.5303 mL 7.0607 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5303 mL 17.6516 mL 35.3033 mL 88.2581 mL
5 mM 0.7061 mL 3.5303 mL 7.0607 mL 17.6516 mL
10 mM 0.3530 mL 1.7652 mL 3.5303 mL 8.8258 mL
15 mM 0.2354 mL 1.1768 mL 2.3536 mL 5.8839 mL
20 mM 0.1765 mL 0.8826 mL 1.7652 mL 4.4129 mL
25 mM 0.1412 mL 0.7061 mL 1.4121 mL 3.5303 mL
30 mM 0.1177 mL 0.5884 mL 1.1768 mL 2.9419 mL
40 mM 0.0883 mL 0.4413 mL 0.8826 mL 2.2065 mL
50 mM 0.0706 mL 0.3530 mL 0.7061 mL 1.7652 mL
60 mM 0.0588 mL 0.2942 mL 0.5884 mL 1.4710 mL
80 mM 0.0441 mL 0.2206 mL 0.4413 mL 1.1032 mL
100 mM 0.0353 mL 0.1765 mL 0.3530 mL 0.8826 mL
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Sulfamethoxazole-NO Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sulfamethoxazole-NO29699-89-6SMX-NOOthersSulfonamide allergyimmunogenicitycytotoxicitytissue proteinsantigenicityInhibitorinhibitorinhibit

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