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  5. Mannosamine–desthiobiotin adduct

Mannosamine-desthiobiotin adduct (compound MDTBA) is a carrier immunogenicity-reducing hapten that reduces the immunogenicity of protein carriers upon conjugation to available free amines on the carrier protein surface. Conjugation of Mannosamine-desthiobiotin adduct to hsIgG significantly (>1-fold) reduced the immunogenicity of hsIgG. Mannosamine-desthiobiotin adduct can be used in antigen design research.

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Mannosamine–desthiobiotin adduct Chemical Structure

Mannosamine–desthiobiotin adduct Chemical Structure

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Mannosamine–desthiobiotin adduct Related Antibodies

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Description

Mannosamine-desthiobiotin adduct (compound MDTBA) is a carrier immunogenicity-reducing hapten that reduces the immunogenicity of protein carriers upon conjugation to available free amines on the carrier protein surface. Conjugation of Mannosamine-desthiobiotin adduct to hsIgG significantly (>1-fold) reduced the immunogenicity of hsIgG. Mannosamine-desthiobiotin adduct can be used in antigen design research[1].

Molecular Weight

375.42

Formula

C16H29N3O7
SMILES

OC[C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)NC(CCCCCC2C(C)NC(N2)=O)=O)O)O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Mannosamine–desthiobiotin adduct Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mannosamine–desthiobiotin adductOthershsIgGproteinantigenimmunogenicityInhibitorinhibitorinhibit

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Mannosamine–desthiobiotin adduct
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