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human albumin

" in MedChemExpress (MCE) Product Catalog:

35

Inhibitors & Agonists

3

Fluorescent Dye

11

Biochemical Assay Reagents

3

Peptides

10

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5

Natural
Products

5

Recombinant Proteins

3

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-150097

    Biochemical Assay Reagents Others
    Recombinant Human Serum Albumin (rHSA) is an active compound and possesses an identical conformation to plasma derived HSA. Recombinant Human Serum Albumin (rHSA) has no difference between rHSA and plasma derived HSA. Recombinant Human Serum Albumin (rHSA) has high efficacy of rHSA with little or no adverse reaction .
    Recombinant Human Serum Albumin(rHSA)
  • HY-P1956
    Human serum albumin
    1 Publications Verification

    HSA

    NF-κB NO Synthase Cardiovascular Disease Inflammation/Immunology
    Human serum albumin (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, NF-κB, and peroxynitrite (ONOO ) in the vascular wall, contributing to the reduction of blood pressure .
    Human serum albumin
  • HY-NP032

    HSA-Cy5

    Fluorescent Dye Others
    Human Sermu Albumin-Cy5 is Cy5-labeled Human serum albumin (HAS, HY-P1956) .
    Human Serum Albumin-Cy5
  • HY-NP060

    HSA-AF488

    Biochemical Assay Reagents Others
    Human Serum Albumin-AF488 is a biochemical reagent conjugated to fluorescein AF488 (Ex=488 nm; Em=496 nm). Human Serum Albumin-AF488 can be used to label or detect specific antigens, molecules or cellular structures .
    Human Serum Albumin-AF488
  • HY-NP050

    HSA-AF647

    Biochemical Assay Reagents Others
    Human Serum Albumin-AF647 (HSA-AF647) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
    Human Serum Albumin-AF647
  • HY-NP027

    HSA-Cy3

    Biochemical Assay Reagents Fluorescent Dye Others
    Human Serum Albumin-Cy3 is a human serum albumin conjugated with Cy3 (Ex=554 nm; Em=568 nm). Human Serum Albumin-Cy3 can be used as a fluorescent marker to label or detect specific antigens, molecules or cell structures .
    Human Serum Albumin-Cy3
  • HY-NP054

    HSA-APC; ApC-HSA

    Biochemical Assay Reagents Others
    Human Serum Albumin-APC (HSA-APC) is human serum albumin (HSA) labeled with allophycocyanin (APC) (HY-D1815) and can be used for fluorescent labeling and tracing experiments.
    Human Serum Albumin-APC
  • HY-NP031

    HSA-AF555

    Biochemical Assay Reagents Others
    Human Serum Albumin-AF555 is an AF555 conjugated HSA (Ex=752 nM, Em=780 nm). Human Serum Albumin-AF555 can be used in the research of cell interaction .
    Human Serum Albumin-AF555
  • HY-NP029

    HSA-RBITC

    Biochemical Assay Reagents Others
    Human Sermu Albumin-RBITC (HSA-RBITC) is a kind of biological materials or organic compounds that are widely used in life science research .
    Human Serum Albumin-RBITC
  • HY-P99696

    LIB003

    PCSK9 Cardiovascular Disease Metabolic Disease
    Lerodalcibep (LIB003) is a recombinant fusion protein of a PCSK9-binding domain (adnectin) and human serum albumin. Lerodalcibep is a Lipid-lowering agent. Lerodalcibep can be used for the research of hypercholesterolemia and cardiovascular diseases .
    Lerodalcibep
  • HY-P99397

    ALX 0761; M 1095

    Interleukin Related MMP Inflammation/Immunology
    Sonelokimab (ALX 0761) is a trivalent bispecific nanobody composed of camel derived humanized IL-17F antibodies, IL-17A/F antibodies, and serum albumin VHH antibodies. Sonelokimab can prolong the plasma half-life by binding to human serum albumin. Sonelokimab can be used for research on rheumatoid arthritis and psoriasis .
    Sonelokimab
  • HY-P1956A

    HSA (Cell culture grade, Endotoxin<0.125 EU/mg)

    NF-κB NO Synthase Cardiovascular Disease Inflammation/Immunology
    Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, iNOS, and peroxynitrite (ONOO ) in the vascular wall, contributing to the reduction of blood pressure .
    Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg)
  • HY-150978

    Fluorescent Dye Others
    DDAO-C6 is a cridone ester derivative, highly specific fluorescence for detecting human serum albumin (HSA). DDAO-C6 acts as an enzymatic activatable near-infrared fluorescent probe in visually sensing endogenous lipase from gut microbes (Ex/Em=600/658 nm) .
    DDAO-C6
  • HY-139248

    Others Cancer
    Paclitaxel octadecanedioate (compound PTX-FA18) is comprised of Paclitaxel (HY-B0015) conjugated to 1,18-octadecanedioic acid (HY-W005178). Paclitaxel octadecanedioate mixed with human serum albumin (HAS) is cytotoxic to HT-1080, PANC-1, HT-29 and Hela cells (IC50s = 12, 2.48, 8.62, and 64.42 nM, respectively) .
    Paclitaxel octadecanedioate
  • HY-P99974

    Nanoparticle albumin-bound Paclitaxel; Nanoparticle albumin-bound ABI-007

    Microtubule/Tubulin Apoptosis Autophagy Cancer
    Nab-Paclitaxel is an albumin-bound nanoparticle formulation of Paclitaxel (HY-B0015). Nab-Paclitaxel is composed of albumin and the active pharmaceutical ingredient Paclitaxel (Paclitaxel: human albumin=1:9), in which human albumin is used as an excipient to disperse and stabilize particles and carry the main drug. Nab-Paclitaxel was associated with higher response rates and better tolerability, with favorable pharmacokinetic properties . (The product size below only indicate the effective content of Paclitaxel. The actual albumin quality depends on the batch. The ratio of each component in this product is Paclitaxel: albumin = 1:7-1:11.)
    Nab-Paclitaxel
  • HY-N12329

    Others Others
    Fumonisin B4 is a derivative of fumonisin. Fumonisin B4 has low albumin binding capacity .
    Fumonisin B4
  • HY-P99385

    ALX-0061

    Interleukin Related Inflammation/Immunology
    Vobarilizumab (ALX-0061) is a humanized bispecific anti-IL-6R and anti-human serum albumin (ALB) monoclonal antibody (mAb) (Kd: 0.19 pM). Vobarilizumab consists of an anti-IL-6R domain and an anti-human serum albumin domain. Vobarilizumab can be used in the research of inflammatory autoimmune diseases, such as rheumatoid arthritis .
    Vobarilizumab
  • HY-D0022

    5-AF

    Fluorescent Dye Others
    5-Aminofluorescein (5-AF) is a fluorescence marker, covalently bound to human serum albumin. The excitation wavelength is 495 nm and the emission wavelength is 535 nm .
    5-Aminofluorescein
  • HY-P99638

    ALXN-1720

    Complement System Inflammation/Immunology
    Gefurulimab (ALXN-1720) is a human-derived bispecific antibody against complement C5 and albumin that binds C5 and blocks its activation .
    Gefurulimab
  • HY-P99796

    ATN-103

    TNF Receptor Inflammation/Immunology
    Ozoralizumab (ATN-103) is an anti-TNFα humanized antibody. Ozoralizumab is a humanized trivalent nanobody compound that consists of two anti-human TNFα nanobodies and an anti-human serum albumin (HSA) nanobody. Ozoralizumab can be used in research of arthritis .
    Ozoralizumab
  • HY-107091

    DA-DKP

    Others Inflammation/Immunology
    Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin and can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy .
    Aspartyl-alanyl-diketopiperazine
  • HY-P4290

    Endogenous Metabolite Endocrinology
    Antiulcer Agent 2 is a tetrapeptide containing aspartic acid, alanine, histidine, and lysine. Antiulcer Agent 2 is present at the N-terminal of human albumin. Antiulcer Agent 2 has potential applications in ulcers and active oxygen generation .
    Antiulcer Agent 2
  • HY-117909

    RXDX-107

    Apoptosis Cancer
    CEP-40125 (RXDX-107) is a modified form of Bendamustine (HY-13567), a DNA cross-linking agent that may cause DNA damage and cell apoptosis. CEP-40125 (RXDX-107) is formed by encapsulating the alkyl ester form of Bendamustine in human serum albumin .
    CEP-40125
  • HY-D1739

    Fluorescent Dye Carboxylesterase Others
    DDAO phosphate diammonium is a fluorescent phosphatase substrate. DDAO phosphate diammonium has tunable excitation wavelength (600-650nm) and long emission wavelength (λem=656nm). DDAO phosphate diammonium can be used to detect the activity of different enzymes such as β-galactosidase, sulfatase, protein phosphatase 2A, carboxylesterase 2, human albumin and esterase.
    DDAO phosphate diammonium
  • HY-122324

    (+)-(S)-Tylophorine; DCB-3500; NSC-717335

    Others Cancer
    Tylophorine and its analogs are benzoindole alkaloids, most of which are derived from Garcinia plants. Tylophorine analogs all show potent growth inhibition against human hepatocellular carcinoma HepG2 and human nasopharyngeal carcinoma KB cell lines. Tylophorine analogs can also induce increased albumin expression and inhibit α-fetoprotein expression in HepG2 cells, and have the potential to induce HepG2 cell differentiation .
    Tylophorine
  • HY-N2252

    (+)-Licarin A

    TNF Receptor Prostaglandin Receptor COX Neurological Disease Metabolic Disease Inflammation/Immunology
    Licarin A ((+)-Licarin A), a neolignan, significantly and dose-dependently reduces TNF-α production (IC50=12.6 μM) in dinitrophenyl-human serum albumin (DNP-HSA)-stimulated RBL-2H3 cells. Anti-allergic effects. Licarin A reduces TNF-α and PGD2 production, and COX-2 expression .
    Licarin A
  • HY-116870

    Others Infection
    Vamidothion is a polar organophosphorus insecticide and acaricide with biological activity against insects and mites. Vamidothion is degraded by human serum albumin (HSA) and promotes adduct formation with tyrosine residues. The phosphate amino acid adducts formed after the reaction of vamidothion with HSA are detected by liquid chromatography quadrupole-Orbitrap mass spectrometry. The metabolites of vamidothion can be used in forensic toxicology to help determine deaths caused by organophosphorus poisoning .
    Vamidothion
  • HY-14744B

    (S)-Amlodipine hydrochloride; Levoamlodipine hydrochloride

    Calcium Channel Cardiovascular Disease
    Levamlodipine hydrochloride (Levoamlodipine hydrochloride) is a dihydropyridine calcium channel blocker. Levamlodipine hydrochloride reduces the inflow of calcium ions by blocking L-type calcium channels on vascular smooth muscle cells, thereby leading to vasodilation, lower blood pressure and lighten the burden on the heart. Levamlodipine hydrochloride has activity to lower blood pressure and relieve angina. The binding properties of Levamlodipine hydrochloride to human serum albumin (HSA) contribute to the study of drug transport and release mechanisms in the body .
    Levamlodipine hydrochloride
  • HY-118124

    Others Others
    2-Iodoestradiol is a potent human sex hormone binding globulin (SHBG) ligand with a remarkably high affinity for SHBG. 2-Iodoestradiol exhibits competition for the same binding site as dihydrotestosterone in binding to human SHBG. The binding affinity constant of 2-Iodoestradiol at physiological pH and 37 degrees Celsius is 2.4 x 10(9) M-1, exceeding that for SHBG. 2-Iodoestradiol has been shown to bind to serum albumin, but with lower affinity. The radioisotope 125I-derivative of 2-Iodoestradiol has been used to study the binding properties of human SHBG, demonstrating its potential application in biological research .
    2-Iodoestradiol
  • HY-135541

    YM150 maleate

    Others Cardiovascular Disease
    Darexaban maleate (YM150 maleate) is a direct factor Xa inhibitor with activity in preventing venous thromboembolism. The major metabolite of Darexaban maleate in humans is Darexaban glucitol, which acts pharmacologically. The glucitolation reaction of Darexaban maleate is mainly catalyzed by UGT1A9 and UGT1A10 in the human liver and intestine. The K(m) value of Darexaban maleate glucitolation in the liver is greater than 250 μM, while in the intestine it exhibits substrate inhibition kinetics with a K(m) value of 27.3 μM. The unbound K(m) value of Darexaban maleate is significantly reduced by the influence of fatty acid-free bovine serum albumin in both HLM and UGT1A9 .
    Darexaban maleate
  • HY-108795A

    GLP-1-Gly8 TFA; GLP-1 (7-36) analog TFA

    GLP Receptor Metabolic Disease
    Albiglutide fragment (GLP-1 (7-36) analog) TFA is an active fragment of Albiglutide (7-36) and a glucagon-like peptide-1 (GLP-1) analog (a long-acting GLP-1 receptor agonist). Albiglutide is produced by the fusion of DPP-4 resistant GLP-1 dimer with the human albumin gene. Moreover, Albiglutide fragment TFA significantly reduces glycosylated hemoglobin (A1C) and is used in type 2 diabetes (T2D) studies .
    Albiglutide fragment TFA
  • HY-108795

    GLP-1-Gly8; GLP-1 (7-36) analog

    GLP Receptor Metabolic Disease
    Albiglutide fragment (GLP-1 (7-36) analog) is an active fragment of Albiglutide (7-36) and a glucagon-like peptide-1 (GLP-1) analog (a long-acting GLP-1 receptor agonist). Albiglutide is produced by the fusion of DPP-4 resistant GLP-1 dimer with the human albumin gene. Moreover, Albiglutide fragment significantly reduces glycosylated hemoglobin (A1C) and is used in type 2 diabetes (T2D) studies .
    Albiglutide fragment
  • HY-159563

    Drug-Linker Conjugates for ADC Cancer
    Mal-va-mac-SN38 is a drug-linker conjugate for ADC. Mal-va-mac-SN38 contains a ADC cytotoxin SN-38 (HY-13704) and a linker (HY-126364). Mal-va-mac-SN38 can rapidly and covalently bind with endogenous albumin in vivo, resulting in the formation of HSA-va-mac-SN38. Mal-va-mac-SN38 demonstrates exceptional stability in human plasma, and has anti-tumor and anti-metastasis effect .
    Mal-va-mac-SN38
  • HY-121535

    Others Others
    Levosemotiadil, an S-isomer of semotiadil, exhibits stronger binding affinity to human serum albumin (HSA) compared to its R-isomer counterpart. This study utilized high-performance frontal analysis (HPFA) to demonstrate that levosemotiadil binds approximately three times more strongly to HSA than semotiadil. The binding parameters were evaluated using Scatchard analysis, revealing specific interactions with the diazepam binding site on HSA. The presence of diazepam decreased the binding affinity of both enantiomers, while warfarin did not alter their binding characteristics. These findings highlight levosemotiadil's potential as a Ca- and Na-channel blocker with significant binding preferences for HSA, crucial for understanding its pharmacokinetics and therapeutic effects .
    Levosemotiadil
  • HY-120828

    CJC 1134PC

    GLP Receptor Metabolic Disease
    Albenatide (CJC 1134PC) is a modified Exendin-4 (HY-13443) analogue conjugated to human recombinant albumin (HRA) in vitro to form a long-acting DPP-4-resistant GLP-1R agonist. Albenatide covalently binds through a low-molecular chemical linker (cys-C13H19O6N3-lys) to the cysteine residue in position 34 of HRA. Albenatide increases cyclic AMP (cAMP) production in vitro. Albenatide reduces glucose excursions, food intake, gastric emptying in wild-type mice and improves glucose tolerance and reduces body weight in high-fat diet mice .
    Albenatide

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