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  3. Paclitaxel octadecanedioate

Paclitaxel octadecanedioate (compound PTX-FA18) is comprised of Paclitaxel (HY-B0015) conjugated to 1,18-octadecanedioic acid (HY-W005178). Paclitaxel octadecanedioate mixed with human serum albumin (HAS) is cytotoxic to HT-1080, PANC-1, HT-29 and Hela cells (IC50s = 12, 2.48, 8.62, and 64.42 nM, respectively).

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Paclitaxel octadecanedioate Chemical Structure

Paclitaxel octadecanedioate Chemical Structure

CAS No. : 2089211-45-8

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Description

Paclitaxel octadecanedioate (compound PTX-FA18) is comprised of Paclitaxel (HY-B0015) conjugated to 1,18-octadecanedioic acid (HY-W005178). Paclitaxel octadecanedioate mixed with human serum albumin (HAS) is cytotoxic to HT-1080, PANC-1, HT-29 and Hela cells (IC50s = 12, 2.48, 8.62, and 64.42 nM, respectively)[1].

Molecular Weight

1150.35

Formula

C65H83NO17

CAS No.
SMILES

CC(O[C@]12[C@@]3([H])[C@@H]([C@]4(C(C)(C([C@H](C([C@@]3([C@H](C[C@@]1([H])OC2)O)C)=O)OC(C)=O)=C([C@H](C4)OC([C@H](OC(CCCCCCCCCCCCCCCCC(O)=O)=O)[C@H](C5=CC=CC=C5)NC(C6=CC=CC=C6)=O)=O)C)C)O)OC(C7=CC=CC=C7)=O)=O

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Paclitaxel octadecanedioate Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Paclitaxel octadecanedioate
Cat. No.:
HY-139248
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