Levamlodipine hydrochloride  (Synonyms: (S)-Amlodipine hydrochloride; Levoamlodipine hydrochloride)

Levamlodipine hydrochloride (Levoamlodipine hydrochloride) is a dihydropyridine calcium channel blocker. Levamlodipine hydrochloride reduces the inflow of calcium ions by blocking L-type calcium channels on vascular smooth muscle cells, thereby leading to vasodilation, lower blood pressure and lighten the burden on the heart. Levamlodipine hydrochloride has activity to lower blood pressure and relieve angina. The binding properties of Levamlodipine hydrochloride to human serum albumin (HSA) contribute to the study of drug transport and release mechanisms in the body^[1].

445.34

C₂₀H₂₆Cl₂N₂O₅

865430-76-8

O=C(C1=C(COCCN)NC(C)=C(C(OC)=O)[C@@H]1C2=CC=CC=C2Cl)OCC.[H]Cl

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Dai G Y,et al. Clinical assessment of levamlodipine besylate combination therapy for essential hypertension: A protocol for systematic review and meta-analysis[J]. Medicine, 2022, 101(13): e29148.  [Content Brief]

  [2]. Liu Z, et al. Affinity and specificity of levamlodipine-human serum albumin interactions: insights into its carrier function[J]. Biophysical journal, 2009, 96(10): 3917-3925.  [Content Brief]