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Results for "

marine alkaloid

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

12

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101848
    Latrunculin B

    		Fungal Infection
    Latrunculin B, an antimicrobial marine alkaloid, is an actin polymerization inhibitor. Latrunculin B regulates pulmonary vein electrophysiological characteristics and attenuates stretch-induced arrhythmogenesis. Antifungal and antiprotozoal activity .
    Latrunculin B
  • HY-W001963
    Pyrrole-2-carboxylic acid

    		Endogenous Metabolite Others
    Pyrrole-2-carboxylic acid is a natural alkaloid from the marine bacterium Pelomonas puraquae sp. Nov.
    Pyrrole-2-carboxylic acid
  • HY-125538
    Deoxybrevianamide E

    		Endogenous Metabolite Inflammation/Immunology
    Deoxybrevianamide E, an indole alkaloid, is a biosynthetic precursor for advanced metabolites isolated from the marine-derived Aspergillus sp. .
    Deoxybrevianamide E
  • HY-116436
    Clathrodin

    		Sodium Channel Neurological Disease
    Clathrodin is a marine alkaloid that can be isolated from sponges of the genus, Agelas. Clathrodin is a modulator of voltage-gated sodium (NaV) channels. Clathrodin is a sodium channel neurotoxin influencing sodium channel ionic conductance .
    Clathrodin
  • HY-N6095
    Nocarimidazole A

    		Others Others
    Nocarimidazole A is a white amorphous solid alkaloid with ultraviolet activity that can be isolated from marine actinomycete Nocardiopsis .
    Nocarimidazole A
  • HY-130995
    Agrochelin

    		Antibiotic ADC Cytotoxin Infection
    Agrochelin, an alkaloid cytotoxic antibiotic, is produced by the fermentation of a marine Agrobacterium sp. Agrochelin has cytotoxic activity in tumor cell lines .
    Agrochelin
  • HY-116529
    Lamellarin E

    		Others Others
    Lamellarin E is a biologically active marine alkaloid, while the Lamellarin series of alkaloids show potential cytotoxicity, topoisomerase I inhibition, protein kinase inhibition, multidrug resistance reversal, and anti-HIV-1 activity .
    Lamellarin E
  • HY-N6997
    Ceratamine A

    		Microtubule/Tubulin Cancer
    Ceratamine A is an antimitotic heterocyclic alkaloid isolated from the marine sponge Pseudoceratina sp., acts as a microtubule-stabilizing agent. Ceratamine A exhibits cytotoxicity against human cancer cell lines .
    Ceratamine A
  • HY-121014
    Amphimedine

    		Others Cancer
    Amphimedine is a polycyclic alkaloid isolated from the marine sponge Amphimedon sp. and belongs to the pyridoindole alkaloid class. Amphimedine has cytotoxic activity and has been studied as an anticancer metabolite along with neoamphimedine. Studies have shown that deoxyamphimedine damages DNA by generating reactive oxygen species, a mechanism different from that of amphimedine.
    Amphimedine
  • HY-N10256
    Varioxepine A

    		Endogenous Metabolite Infection
    Varioxepine A is a 3H-oxepine-containing alkaloid with a new oxa-cage found in the marine algal-derived endophytic fungus Paecilomyces variotii. Varioxepine A inhibits plant pathogenic fungus Fusarium graminearum .
    Varioxepine A
  • HY-125097
    5'-Hydroxy-staurosporine

    		Others Cancer
    5'-Hydroxy-staurosporine is an indolocarbazole alkaloid that can be isolated from marine Micromonospora sp. (strain L-31-CLCO-002). 5'-Hydroxy-staurosporine can be used in tumor related research .
    5'-Hydroxy-staurosporine
  • HY-W065835
    2-Bromoaldisine

    		HIV Infection
    2-Bromoaldisine is a pyrrole alkaloid that can be isolated from the Red Sea: marine sponge Stylissa carter. 2-Bromoaldisine inhibits HIV-1 vector infection. 2-Bromoaldisine inhibits Raf/MEK/MAPK pathway .
    2-Bromoaldisine
  • HY-126601
    Malonganenone A

    		Parasite HSP Infection
    Malonganenone A is an antimalarial marine alkaloid that disrupts the interaction between PfHsp70-x and Hsp40. Malonganenone A inhibits plasmodial and not human Hsp70 ATPase activity (Hsp40-stimulated), and hindered the aggregation suppression activity of PfHsp70-x .
    Malonganenone A
  • HY-N12726
    Halociline

    		p38 MAPK MMP Infection Inflammation/Immunology Cancer
    Halociline, a derivative of alkaloids, that can be isolated from the marine fungus Penicillium griseofulvum. Halociline targets MAPK1, MMP-9, and PIK3CA in gastric cancer cells, potentially mediated by diverse pathways including cancer, lipid metabolism, atherosclerosis, and EGFR tyrosine kinase inhibitor resistance. Halociline possesses antimicrobial, antioxidant and biofilm inhibitory activities .
    Halociline
  • HY-155852
    Lepadin H

    		Ferroptosis Others
    Lepadin H is a marine alkaloid and ferroptosis inducer. Lepadin H exhibits significant cytotoxicity, promotes p53 expression, increases ROS production and lipid peroxidation, decreases SLC7A11 and GPX4 levels, and upregulates ACSL4 expression. Lepadin H induces ferroptosis through the p53-SLC7A11-GPX4 pathway .
    Lepadin H

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