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  3. Parasite HSP
  4. Malonganenone A

Malonganenone A is an antimalarial marine alkaloid that disrupts the interaction between PfHsp70-x and Hsp40. Malonganenone A inhibits plasmodial and not human Hsp70 ATPase activity (Hsp40-stimulated), and hindered the aggregation suppression activity of PfHsp70-x.

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Malonganenone A Chemical Structure

Malonganenone A Chemical Structure

CAS No. : 882403-69-2

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Malonganenone A Related Antibodies

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Description

Malonganenone A is an antimalarial marine alkaloid that disrupts the interaction between PfHsp70-x and Hsp40. Malonganenone A inhibits plasmodial and not human Hsp70 ATPase activity (Hsp40-stimulated), and hindered the aggregation suppression activity of PfHsp70-x[1].

Molecular Weight

438.61

Formula

C26H38N4O2
CAS No.
SMILES

O=C1N=CN(C)C2=C1N(C/C=C(C)/CC/C=C(C)/CCC/C(C)=C\C(CC(C)C)=O)C=N2
Structure Classification
Initial Source

Mozambique gorgonian Leptogorgia gilchristi
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
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Malonganenone A Related Classifications

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Keywords:

Malonganenone A882403-69-2ParasiteHSPHeat shock proteinsantimalarial marinePfHsp70-xHsp40Inhibitorinhibitorinhibit

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