5'-Hydroxy-staurosporine 

5'-Hydroxy-staurosporine is an indolocarbazole alkaloid that can be isolated from marine Micromonospora sp. (strain L-31-CLCO-002). 5'-Hydroxy-staurosporine can be used in tumor related research^[1].

5'-Hydroxy-staurosporine inhibits the activity of P388D1, A549, HT-29 and SK-MEL-28 cells with IC₅₀ values of 0.02 µM, 0.002 µM, 0.004 µM and 0.002 µM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

482.53

C₂₈H₂₆N₄O₄

308847-74-7

O=C1NCC2=C1C3=C(N4C5=CC=CC=C35)C6=C2C7=CC=CC=C7N6[C@@]8([C@@H]([C@@H]([C@H]([C@]4(O8)[H])O)NC)OC)C

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Hernández LM, et al. 4'-N-methyl-5'-hydroxystaurosporine and 5'-hydroxystaurosporine, new indolocarbazole alkaloids from a marine Micromonospora sp. strain. J Antibiot (Tokyo). 2000 Sep;53(9):895-902.  [Content Brief]