quality control

By Targets:	ADC Cytotoxin (1) Deubiquitinase (1) Fungal (1) Mitophagy (1) Opioid Receptor (1) Parasite (2)
By Research Areas:	Cancer (2) Endocrinology (1) Metabolic Disease (1) Neurological Disease (3)
Click Chemistry:	Azide (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N7026

Celosin I	Others	Metabolic Disease
Celosin I, an oleanane-type triterpenoid saponin isolated from the seeds of Celosia argentea L, could be used as chemical markers for the quality control of C. argentea seeds. Celosin I exhibits significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in mice .

HY-118615

LY2048978	Opioid Receptor	Neurological Disease
LY2048978 is a non-selective opioid receptor antagonist with K_i of 0.287, 0.471 and 1.05 nM for human mu, kappa and delta opioid receptors in vitro, respectively. LY2048978 can be used in the research of major depressive disorder and alcohol use disorder .

HY-N0624

Complanatoside A	Others	Cancer
Complanatoside A is a flavonol glycoside isolated from Astragalus complanatus, and currently it is used as a quality control index for A. complanatus in the 2010 edition of the Chinese Pharmacopoeia.

HY-124482

Mesembrenol	Others	Others
Mesembrenol (Chemotype c) is an alkaloid widely found in plants. Mesembrenol has potential application in quality control of raw materials and products of S.tortuosum .

HY-B1337C

Choline (chloride), >98%	Others	Others
Choline (chloride), >98% serves as a pharmaceutical secondary standard for quality control, offering pharmaceutical laboratories and manufacturers a convenient and cost-effective alternative to preparing in-house working standards.

HY-W488109

Genite	Others
Genite is a highly effective pesticide with strong insecticidal activity. Genite can effectively control the number of various pests and is widely used in agricultural production. The use of Genite can significantly increase the yield and quality of crops.

HY-W774918

Oxaziclomefone	Others
Oxaziclomefone is a broad-spectrum pesticide with fungal activity. Oxaziclomefone effectively controls a variety of crop diseases and has significant effects against plant pathogenic fungi. Oxaziclomefone is widely used in agriculture to protect crops from diseases and improve crop yield and quality.

HY-112785

Pyriftalid	Parasite
Pyriftalid is a new type of insecticide with strong inhibitory activity against a variety of pests. Pyriftalid is widely used in agriculture to effectively control pests on crops, thereby improving crop yield and quality. Pyriftalid is also being studied for improving plant resistance to resist attacks by pests and diseases.

HY-W774918R

Oxaziclomefone (Standard)	Fungal
Oxaziclomefone (Standard) is the analytical standard of Oxaziclomefone. This product is intended for research and analytical applications. Oxaziclomefone is a broad-spectrum pesticide with fungal activity. Oxaziclomefone effectively controls a variety of crop diseases and has significant effects against plant pathogenic fungi. Oxaziclomefone is widely used in agriculture to protect crops from diseases and improve crop yield and quality.

HY-B0661C

Tamsolusin hydrochloride YM12617 hydrochloride; LY253351 hydrochloride	Others	Endocrinology
Tamsolusin (YM12617) hydrochloride is a highly selective alpha-1A adrenergic receptor antagonist used in the treatment of benign prostatic hypertrophy, demonstrating effective biological activity in alleviating associated symptoms. Tamsolusin hydrochloride can also be quantified using a validated spectrofluorimetric method, showcasing its potential for routine quality control analysis in pharmaceutical formulations.

HY-N0478

Neoline 1 Publications Verification Bullatine B	Others	Neurological Disease
Neoline (Bullatine B)) is the active ingredient of the active ingredient (PA), which can be used to cure the disease. Neoline Flow Suppression Nav1.7 Electrical Flow Control (VGSC)，Improve diabetes mechanical pain sensitivity. Neoline has a list of compounds that can be used, research on its use, and the quality of its processing during processing in pain.

HY-112785R

Pyriftalid (Standard)	Parasite
Pyriftalid (Standard) is the analytical standard of Pyriftalid. This product is intended for research and analytical applications. Pyriftalid is a new type of insecticide with strong inhibitory activity against a variety of pests. Pyriftalid is widely used in agriculture to effectively control pests on crops, thereby improving crop yield and quality. Pyriftalid is also being studied for improving plant resistance to resist attacks by pests and diseases.

HY-145149

Duostatin 5	ADC Cytotoxin	Cancer
Duostatin 5 is a cytotoxin designed based on dolastatin, can meet the requirement of serving as an effective cytotoxin in ADC, but has the advantages of fewer synthesis steps, easy operation, less difficulty in quality control and more stable chemical synthesis process . Duostatin 5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-P10416

Q14 Q14 peptide	Deubiquitinase Mitophagy	Others Neurological Disease
Q14 is a polypeptide derived from the USP30 (ubiquitin specific peptidase 30) transmembrane (TM) domain with the ability to inhibit the deubiquitination activity of USP30 (IC₅₀=57.2 nM). Q14 reduces USP30 activity by inhibiting the interaction between the USP30 transmembrane domain and its catalytic domain. Q14 peptide contains the LC3 interaction region (LIR) motif, which enables it to bind to the LC3 and accelerate the formation of autophagosomes, thereby promoting mitophagy. Q14 can be used in the study of neurodegenerative diseases as well as mitochondrial quality control and cell metabolism .

Cat. No.	Product Name

HY-L0095V

OTAVAchemicals Screening Collection	270,000 compounds
OTAVAchemicals Screening Collection contains about 270,000 re-supply compounds for prompt delivery. All compounds have undergone quality control to confirm their chemical structures.

HY-L0094V

Chinese National Compound Library	1,398,968 compounds
The Chinese National Compound Library (CNCL) composes 1.4 million compounds possessing diversified structures. Coupled with this library will be advanced sample handling, information management and quality control systems. Most compounds in the library are drug-like, conforming to “Lipinski’s Rule of Five”, such as MW < 500, logP < 5, Hydrogen Bond Donors < 5.

HY-L0114V

Pharmeks Screening Compound Library	439,804 compounds
This library contains about 439,804 natural and synthetic screening compounds. The information in the database includes logP, H-bond donors, H-bond acceptors, rotable bonds.

HY-L0118V

Asinex Covalent Inhibitors Library	942 compounds
A unique set of molecules containing mild electrophilic moieties that covalently interact with amino acid residues in the target protein. The diversity of our compounds for covalent drug discovery ranges from natural product-like scaffolds to macrocycles, creating multiple opportunities in hit generation for a selected target.

Cat. No.	Product Name	Target	Research Area

HY-P10416

Q14 Q14 peptide	Deubiquitinase Mitophagy	Others Neurological Disease
Q14 is a polypeptide derived from the USP30 (ubiquitin specific peptidase 30) transmembrane (TM) domain with the ability to inhibit the deubiquitination activity of USP30 (IC₅₀=57.2 nM). Q14 reduces USP30 activity by inhibiting the interaction between the USP30 transmembrane domain and its catalytic domain. Q14 peptide contains the LC3 interaction region (LIR) motif, which enables it to bind to the LC3 and accelerate the formation of autophagosomes, thereby promoting mitophagy. Q14 can be used in the study of neurodegenerative diseases as well as mitochondrial quality control and cell metabolism .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7026

Celosin I	Triterpenes Celosia argentea Linn. Classification of Application Fields Terpenoids Source classification Metabolic Disease Amaranthaceae Plants Disease Research Fields	Others
Celosin I, an oleanane-type triterpenoid saponin isolated from the seeds of Celosia argentea L, could be used as chemical markers for the quality control of C. argentea seeds. Celosin I exhibits significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in mice .

HY-N0478

Neoline 1 Publications Verification Bullatine B	Alkaloids Piperidine Alkaloids Structural Classification other families Source classification Plants	Others
Neoline (Bullatine B)) is the active ingredient of the active ingredient (PA), which can be used to cure the disease. Neoline Flow Suppression Nav1.7 Electrical Flow Control (VGSC)，Improve diabetes mechanical pain sensitivity. Neoline has a list of compounds that can be used, research on its use, and the quality of its processing during processing in pain.

HY-N0624

Complanatoside A	Flavonols Structural Classification Flavonoids Classification of Application Fields Papilionaceae Source classification Phenols Polyphenols Plants Astragalus complanatus Disease Research Fields Cancer	Others
Complanatoside A is a flavonol glycoside isolated from Astragalus complanatus, and currently it is used as a quality control index for A. complanatus in the 2010 edition of the Chinese Pharmacopoeia.

Cat. No.	Product Name		Classification

HY-145149

Duostatin 5		Azide
Duostatin 5 is a cytotoxin designed based on dolastatin, can meet the requirement of serving as an effective cytotoxin in ADC, but has the advantages of fewer synthesis steps, easy operation, less difficulty in quality control and more stable chemical synthesis process . Duostatin 5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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quality control

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