2. GPCR/G Protein Neuronal Signaling
  3. Opioid Receptor
  4. LY2048978

LY2048978 is a non-selective opioid receptor antagonist with Ki of 0.287, 0.471 and 1.05 nM for human mu, kappa and delta opioid receptors in vitro, respectively. LY2048978 can be used in the research of major depressive disorder and alcohol use disorder.

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LY2048978 Chemical Structure

LY2048978 Chemical Structure

CAS No. : 676495-11-7

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LY2048978 Related Antibodies

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μ Opioid Receptor/MOR κ Opioid Receptor/KOR δ Opioid Receptor/DOR NOP Receptor/ORL1

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Description

LY2048978 is a non-selective opioid receptor antagonist with Ki of 0.287, 0.471 and 1.05 nM for human mu, kappa and delta opioid receptors in vitro, respectively. LY2048978 can be used in the research of major depressive disorder and alcohol use disorder[1].

IC50 & Target[1]

μ Opioid Receptor/MOR

0.287 nM (Ki)

κ Opioid Receptor/KOR

0.471 nM (Ki)

δ Opioid Receptor/DOR

1.05 nM (Ki)

Molecular Weight

312.41

Formula

C19H24N2O2
CAS No.
SMILES

O=C(C1=CC=C(C=C1)OC2=CC=C(C=C2)CNCCCCC)N
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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LY2048978 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LY2048978676495-11-7LY 2048978LY-2048978Opioid Receptornonselectiveantagonistquality controlmajor depressionInhibitorinhibitorinhibit

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