1. Academic Validation
  2. [Genetic effects of the new pesticide rovicurt]

[Genetic effects of the new pesticide rovicurt]

  • Tsitol Genet. 1988 Sep-Oct;22(5):52-5.
P I Tashkhodzhaev A T Dusmetov P R Alimkhodzhaeva M S Gil'dieva B A Abdullaev
PMID: 3227569
Abstract

Administration of rovicoort, a new pesticide, in various single doses (75, 150, 380 mg/kg) to mongrel white male rats intragastrically on empty stomach showed that the doses of 75 and 150 mg/kg stimulated adaptive mechanisms of the organism resulting in the increase of diameter of both seminiferous tubules and the number of Sertoli cells as well as fertilizing capacity of spermatozoa. Dominant lethal mutation in early postmeiotic cells was induced after the drug exposure of 150 and 380 mg/kg doses.

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