1. Vitamin D Related/Nuclear Receptor
  2. Progesterone Receptor
  3. Org-31710

Org-31710 is a specific progesterone receptor (PR) inhibitor. Org-31710 shows antiprogestational effect. Org 31710 abolishes the folic acid (HY-16637)-regulated proliferation and migration in PR positive cancer cell lines. Org 31710 abolishes the folic acid-increased the levels of p-PRA, p-PRB, and p-cSrcY416.

For research use only. We do not sell to patients.

Org-31710 Chemical Structure

Org-31710 Chemical Structure

CAS No. : 118968-41-5

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Description

Org-31710 is a specific progesterone receptor (PR) inhibitor. Org-31710 shows antiprogestational effect. Org 31710 abolishes the folic acid (HY-16637)-regulated proliferation and migration in PR positive cancer cell lines. Org 31710 abolishes the folic acid-increased the levels of p-PRA, p-PRB, and p-cSrcY416[1][2].

Molecular Weight

445.64

Formula

C30H39NO2

CAS No.
SMILES

C[C@@]12[C@](CC[C@@]23CCCO3)([H])[C@@]4([H])C([C@@H](C5=CC=C(C=C5)N(C)C)C1)=C6C([C@@H](C4)C)=CC(CC6)=O

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Org-31710
Cat. No.:
HY-118257
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