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Des 1

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2

Inhibitors & Agonists

1

Isotope-Labeled Compounds

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-132795S
    Des(1-cyclohexanol) Venlafaxine-d6

    		Isotope-Labeled Compounds Others
    Des(1-cyclohexanol) Venlafaxine-d6 is the deuterium labeled Des(1-cyclohexanol) Venlafaxine[1].
    <em>Des(1</em>-cyclohexanol) Venlafaxine-d6
  • HY-163472
    PR280

    		Others Metabolic Disease Cancer
    PR280 is a potent inhibitor of dihydroceramide desaturase 1 (Des1) (IC50=700 nM). PR280 forms hydrogen bonds with the amino acid residues of Des1, and its cyclopropenone group may form a coordination with the iron center, thus stabilizing the binding to the active site of Des1 and inhibiting the sphingosine lipid synthesis pathway of dihydroceramide (dhCer) to form ceramide. PR280 can be used in the study of diseases related to sphingosine lipid metabolism, such as cancer and metabolic diseases .
    PR280

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