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Nephrin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Endogenous Metabolite (1)
By Research Areas:	Metabolic Disease (1)

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Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*Nephrin* Hopane-6α,7β,22-triol	Endogenous Metabolite	Metabolic Disease
Nephrin (Hopane-6α,7β,22-triol) is a cell surface signaling receptor protein with activity in regulating podocyte function. Nephrin plays an important role in the normal function of the kidney's filtration barrier. Nephrin is associated with beta cell survival signals and helps maintain cell survival. Urinary levels of nephrin may be associated with tubular injury and can serve as a biomarker for early acute kidney injury .

Cat. No.	Product Name	Category	Target	Chemical Structure

*Nephrin* Hopane-6α,7β,22-triol	Triterpenes Structural Classification Microorganisms Terpenoids Source classification	Endogenous Metabolite
Nephrin (Hopane-6α,7β,22-triol) is a cell surface signaling receptor protein with activity in regulating podocyte function. Nephrin plays an important role in the normal function of the kidney's filtration barrier. Nephrin is associated with beta cell survival signals and helps maintain cell survival. Urinary levels of nephrin may be associated with tubular injury and can serve as a biomarker for early acute kidney injury .

Species:	Human (4) Mouse (2) Rat (1)
Tag:	His (5) Fc (2)
Source:	HEK293 (7)

Cat. No.	Compare	Product Name	Species	Source

	*KIRREL2/NEPH3 Protein, Human (HEK293, Fc)* Kin of IRRE-like protein 2; Nephrin-like protein 3; NEPH3	Human	HEK293
	KIRREL2/NEPH3 proteins may regulate basal insulin secretion and participate in self-association as homodimers. Functionally, it interacts with NPHS2/podocin, NPHS1 and FYN, contributing to key molecular interactions in cellular processes. KIRREL2/NEPH3 Protein, Human (HEK293, Fc) is the recombinant human-derived KIRREL2/NEPH3 protein, expressed by HEK293 , with C-hFc labeled tag.

	*KIRREL2/NEPH3 Protein, Human (HEK293, His)* Kin of IRRE-like protein 2; Nephrin-like protein 3; NEPH3	Human	HEK293
	KIRREL2/NEPH3 proteins may regulate basal insulin secretion and participate in self-association as homodimers. Functionally, it interacts with NPHS2/podocin, NPHS1 and FYN, contributing to key molecular interactions in cellular processes. KIRREL2/NEPH3 Protein, Human (HEK293, His) is the recombinant human-derived KIRREL2/NEPH3 protein, expressed by HEK293 , with C-His labeled tag.

	*KIRREL3/NEPH2 Protein, Mouse (HEK293, His)* Kin of IRRE-like protein 3; Nephrin-like protein 2; Kiaa1867; Neph2	Mouse	HEK293
	The KIRREL3/NEPH2 protein plays a critical role in the formation of precise synapses, particularly in hippocampal mossy fiber synapses, where it is responsible for coordinating mossy fiber filopodia. It acts in a homologous manner to stabilize filopodia contacts and facilitate subsequent synapse formation. KIRREL3/NEPH2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived KIRREL3/NEPH2 protein, expressed by HEK293 , with C-His labeled tag. The total length of KIRREL3/NEPH2 Protein, Mouse (HEK293, His) is 514 a.a., with molecular weight of ~60-80 kDa.

	*KIRREL3/NEPH2 Protein, Rat (HEK293, His)* Kin of IRRE-like protein 3; Nephrin-like protein 2; Kiaa1867; Neph2	Rat	HEK293
	The KIRREL3/NEPH2 protein plays a critical role in the formation of precise synapses, particularly in hippocampal mossy fiber synapses, where it is responsible for coordinating mossy fiber filopodia. It acts in a homologous manner to stabilize filopodia contacts and facilitate subsequent synapse formation. KIRREL3/NEPH2 Protein, Rat (HEK293, His) is the recombinant rat-derived KIRREL3/NEPH2 protein, expressed by HEK293 , with C-His labeled tag. The total length of KIRREL3/NEPH2 Protein, Rat (HEK293, His) is 502 a.a., with molecular weight of 60-64 kDa.

	*Kirrel1/NEPH1 Protein, Mouse (HEK293, His)* Kin of IRRE-like protein 1; Kin of irregular chiasm-like protein 1; Nephrin-like protein 1; Kirrel1; Neph1	Mouse	HEK293
	The Kirrel1/NEPH1 protein is essential for the normal function of the glomerular filtration barrier, helping to maintain a stable podocyte structure and interdigitated foot processes connected by specialized cell-to-cell junctions called slit septa. Additionally, it acts as a signaling protein that requires the presence of TEC kinase to fully transactivate the transcription factor AP-1. Kirrel1/NEPH1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Kirrel1/NEPH1 protein, expressed by HEK293 , with C-6*His labeled tag.

	*Kirrel1/NEPH1 Protein, Human (HEK293, His)* Kin of IRRE-like protein 1; Kin of irregular chiasm-like protein 1; Nephrin-like protein 1; Kirrel1; Neph1	Human	HEK293
	The Kirrel1/NEPH1 protein is essential for the normal function of the glomerular filtration barrier in the kidney, maintaining stable podocyte structure through finger-like foot processes and gap septal cell-cell junctions. As a signaling molecule, it requires TEC kinase to fully activate the transcription factor AP-1. Kirrel1/NEPH1 Protein, Human (HEK293, His) is the recombinant human-derived Kirrel1/NEPH1 protein, expressed by HEK293 , with C-His labeled tag.

	*Kirrel1/NEPH1 Protein, Human (HEK293, Fc)* Kin of IRRE-like protein 1; Kin of irregular chiasm-like protein 1; Nephrin-like protein 1; Kirrel1; Neph1	Human	HEK293
	The Kirrel1/NEPH1 protein is essential for the normal function of the glomerular filtration barrier in the kidney, maintaining stable podocyte structure through finger-like foot processes and gap septal cell-cell junctions. As a signaling molecule, it requires TEC kinase to fully activate the transcription factor AP-1. Kirrel1/NEPH1 Protein, Human (HEK293, Fc) is the recombinant human-derived Kirrel1/NEPH1 protein, expressed by HEK293 , with C-hFc labeled tag.

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