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Results for "

Wnt1

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-RS15827
    WNT1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    WNT1 Human Pre-designed siRNA Set A contains three designed siRNAs for WNT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    WNT1 Human Pre-designed siRNA Set A
    WNT1 Human Pre-designed siRNA Set A
  • HY-164528
    SJ26

    		Wnt G-quadruplex Cancer
    SJ26 is a Wnt1 inhibitor with anticancer activity. SJ26 inhibits the expression of Wnt1 and Wnt1-mediated downstream signaling pathways in a G-quadruplex structure-dependent manner to suppress the migration activity of cancer cells [1].
    SJ26
  • HY-123334
    GNF-1331

    		Porcupine Wnt Cancer
    GNF-1331 (compound 19) is a potent, selective and orally bioavailable porcupine inhibitor (IC50=12 nM). GNF-1331 blocks Wnt ligand secretion and subsequent Wnt signaling activity, and induces significant antitumor effects in the mouse MMTV-WNT1 xenograft tumor model [1].
    GNF-1331
  • HY-164547
    WHN-88

    		Porcupine Wnt β-catenin Cancer
    WHN-88 is a Porcupine (PORCN) inhibitor. WHN-88 can eliminate the palmitoylation of Wnt ligands, preventing their secretion and subsequent Wnt/β-catenin signaling. WHN-88 can inhibit cancer cell stemness and suppress the occurrence and development of breast tumors in MMTV-Wnt1 transgenic mice [1].
    WHN-88

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