Search Result
Results for "
biotin-labeled
" in MedChemExpress (MCE) Product Catalog:
5
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-146244A
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
Biotin-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. Biotin-labeled Agatolimod (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
-
- HY-146245A
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
Biotin-labeled ODN 1826 (sodium), a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. Biotin-labeled ODN 1826 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
-
- HY-P2609F
-
|
|
PACAP Receptor
|
Others
|
|
PACAP (1-38), amide, Biotin-labeled is a biological active peptide. (Biotin-labeled HY-P0221)
|
-
-
- HY-150751A
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
Biotin-labeled ODN TTAGGG (sodium), a inhibitory oligonucleotide (ODN), is a TLR9, AIM2 and cGAS antagonist. Biotin-labeled ODN TTAGGG (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
-
- HY-150724A
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
Biotin-labeled ODN 1018 (sodium), an oligodeoxynucleotide, is a TLR-9 agonist. Biotin-labeled ODN 1018 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
-
- HY-150743A
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
Biotin-labeled ODN 2395 (sodium), a C class oligodeoxynucleotide, is a TLR9 agonist. Biotin-labeled ODN 2395 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
-
- HY-150725A
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
Biotin-labeled ODN 1585 (sodium) is a potent inducer of IFN and TNFα production. Biotin-labeled ODN 1585 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
-
- HY-150738A
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
Biotin-labeled ODN 2088 (sodium) is a potent TLR3, TLR7 and TLR9 inhibitor. Biotin-labeled ODN 2088 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
-
- HY-150726A
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
Biotin-labeled ODN 1668 (sodium), a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. Biotin-labeled ODN 1668 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
-
- HY-150741A
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
Biotin-labeled ODN 2216 (sodium) is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. Biotin-labeled ODN 2216 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
-
- HY-P2491
-
|
|
Fluorescent Dye
|
Cardiovascular Disease
Endocrinology
|
|
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for cardiovascular diseases research .
|
-
-
- HY-P2504
-
|
|
Syk
|
Others
|
|
Syk Kinase Peptide Substrate, Biotin labeled is a biotin-labled Syk kinase peptide substrate.
|
-
-
- HY-145057
-
|
|
Others
|
Cancer
|
|
PP-biotin is an irreversible, biotin-labeled probe .
|
-
-
- HY-161809
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-phosphorylamino-inosine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-152965
-
-
-
- HY-P1032F
-
|
|
Endogenous Metabolite
|
Endocrinology
|
|
Biotinyl-Angiotensin I (human, mouse, rat) is biotin-labeled Angiotensin I . Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE) .
|
-
-
- HY-135641
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-probe 1 is a non-radiolabeled probe. Biotin-labeled probes can be applied to in situ hybridization .
|
-
-
- HY-100894
-
|
|
Caspase
|
Cancer
|
|
Biotin-VAD-FMK is a cell permeable, irreversible biotin-labeled caspase inhibitor, used to identify active caspases in cell lysates.
|
-
-
- HY-116027
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG3-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140492
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG8-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140493
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG12-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140888
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG2-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140889
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140893
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG6-alcohol is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140895
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140896
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG5-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140899
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG8-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140900
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG11-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140907
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG3-Mal is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140908
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG6-Mal is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140932
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-hydrazide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140943
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG7-thiourea is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-140934
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG2-NH-Boc is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-130477
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-Lys (biotin-PEG4)-OH is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-D2355
-
|
|
Biochemical Assay Reagents
|
Others
|
|
tris-NTA Biotin is a biotin-labeled tris-NTA. tris-NTA Biotin can be used as a reversible probe to label proteins and cell surfaces reversibly .
|
-
-
- HY-127049
-
|
|
Fluorescent Dye
|
Others
|
|
Arachidonic acid-Biotin is a biotin-labeled Arachidonic acid (HY-109590) that can be used to detect complexes of arachidonic acid with protein binding partners such as fatty acid binding proteins (FABPs) .
|
-
-
- HY-140532
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Amino-PEG4)-N-Biotin-PEG4-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-158099
-
|
Celastrol-biotin
|
Biochemical Assay Reagents
|
Cancer
|
|
Biotin-Cel (Celastrol-Biotin) is a biotin-labeled Celastrol (HY-13067). Celastrol exhibits antitumor, anti-inflammatory, and anti-obesity activities. Biotin-Cel can be used in biotin-affinity pulldown assay to identify the molecular target of Celastrol in hepatocellular carcinoma cells .
|
-
-
- HY-140922
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-alkyne is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
-
- HY-147206
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-PEG-Alk (MW 600) is a Biotin-labeled Alkyne functionalized polyethylene glycol. Biotin-PEG-Alk (MW 600) can be used to modify proteins, peptides, and oligonucleotides . Biotin-PEG-Alk (MW 600) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
-
- HY-D2353
-
|
|
DNA/RNA Synthesis
|
Cancer
|
|
Biotin-PEG3-benzophenone is biotin-labeled Benzophenone (HY-Y0546). Benzophenone is an endogenous metabolite and a photosensitizer that has been implicated in photosensitive damage to DNA. Benzophenone causes nucleobase oxidation, formation of cyclobutane-pyrimidine dimers, single-strand breaks, DNA-protein cross-links or abasic sites, different pathologies that may occur in nucleosides, oligonucleotides or DNA .
|
-
-
- HY-W156324
-
|
|
PROTAC Linkers
Liposome
|
Others
|
|
Biotin-PEGn-NHS ester is a biotin-labeled PROTAC linker, which belongs to the PEG class and can be used to synthesize PROTAC molecules. Biotin-PEGn-NHS ester can interact with free neutral avidin in solution and successfully target malignant glioma cells. Biotin-PEGn-NHS ester can also be grafted onto the amino group of GelMA to prepare biotin-modified functionalized hydrogel, gelatin methacryloyl (Bio-GelMA) .
|
-
-
- HY-140910
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
-
- HY-140911
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG6-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
-
- HY-139107
-
|
|
ADC Linker
|
Cancer
|
|
Biotin-PEG4-SS-azide is a cleavable, biotin-labeled, ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Biotin-PEG4-SS-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
-
- HY-D1669
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-11-UTP is a Biotin-labeled uridine triphosphate (UTP), containing 11 atoms in the linker between biotin and UTP. Biotin-11-UTP can biotinylate transcribed RNA in vitro and has been widely used as labeling RNA probe . Biotin-11-UTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
-
- HY-132276
-
|
|
Others
|
Others
|
|
PtdIns-(3,4,5)-P3-biotin sodium is a Biotin-labeled PtdIns-(3,4,5)-P3 (PI(3,4,5)P3). PI(3,4,5)P3 is a substrate of nuclear phosphatidylinositol 5-phosphatase (PIP5Pase). PI(3,4,5)P3 binds to the N-terminus of RAP1 (repressor activator protein 1) and controls its DNA binding activity .
|
-
-
- HY-145445
-
-
-
- HY-157221
-
-
-
- HY-P2510
-
|
|
Thyroid Hormone Receptor
|
Metabolic Disease
|
|
Parathyroid Hormone (1-34), human, biotinylated is a probe for the parathyroid hormone receptor, can be used for analyzing the interaction between parathyroid hormone and parathyroid hormone receptors in living cells and for purifying hormone-receptor complexes with affinity columns .
|
-
- HY-P2549
-
-
- HY-P2551
-
|
|
Amyloid-β
|
Neurological Disease
|
|
Biotin-β-Amyloid (17-40) is a N-terminal-labelled biotinylated amyloid-?-(1-40) peptide. β-Amyloid (17-40) is a 24-residue fragment of the Aβ protein via?post-translational processing of amyloid precursor protein (APP) .
|
-
- HY-D0183
-
|
|
Biochemical Assay Reagents
|
Others
|
|
ATP-polyamine-biotin, the first cell-permeable ATP analogue, is an efficient kinase cosubstrate. ATP-polyamine-biotin promotes biotin labeling of kinase substrates in live cells .
|
-
- HY-P1264F1
-
|
|
nAChR
|
Neurological Disease
|
|
Biotin-α-Bungarotoxin is the Biotin labelled α-Bungarotoxin (HY-P1264). α-Bungarotoxin is a competitive antagonist at nicotinic acetylcholine receptors (nAChRs) .
|
-
- HY-140656F
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-PEG-Biotin (MW 20000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity.
|
-
- HY-B2227F
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Lactate-Biotin is the biotin labeled Lactate (HY-B2227). Lactate-Biotin is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-P2546
-
|
|
Neurokinin Receptor
|
Neurological Disease
|
|
Biotin-Substance P is the biotin tagged Substance P. Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R) .
|
-
- HY-P3576
-
|
|
Fluorescent Dye
|
Neurological Disease
Cancer
|
|
Biotin-Gastrin Releasing Peptide, human is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties .
|
-
- HY-P10569
-
|
|
EGFR
|
Cancer
|
|
Biotin HER-2 substrate peptide is a substrate of Her4 and Her2/neu tyrosine kinase with a Km value of 60 μm for Her2/neu kinase domain .
|
-
- HY-P10566
-
|
|
BCL6
|
Cancer
|
|
BCOR(498-514), biotinylated is the minimal BCL6 binding domain with an KD value of 1.32 µM. BCOR(498-514), biotinylated blocks BCL6-mediated transcriptional repression and kills lymphoma cells .
|
-
- HY-154801
-
|
|
Others
|
Others
|
|
Biotin-PEG3-CONH-Ph-CF3-diazirine is a biotin labeled PEG3 derivative. Biotin-PEG3-CONH-Ph-CF3-diazirine can be used for protein labeling .
|
-
- HY-P10372
-
|
|
Src
|
Cancer
|
|
pFYN peptide is a biotin-labled phosphorylated peptide substrate derived from FYN (a Src family kinase) .
|
-
- HY-P3616
-
|
|
GCGR
|
Metabolic Disease
|
|
Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide is a biotin labeled glucagon-like peptide-1-(7-36). Glucagon-like peptide-1-(7-36) is a gastrointestinal peptide with antidiabetogenic activity, and can increase the release of insulin .
|
-
- HY-153797
-
-
- HY-147207A
-
|
|
Liposome
|
Others
|
|
Phospholipid-PEG-Biotin (MW 2000) is a Biotin labeled phospholipid PEG derivative, can be used for modify liposome and cells surface, and pancreatic islets for cell transplantation. Phospholipid is a class of lipid containing a hydrophilic “head” and two hydrophobic “tails”; PEG is a hydrophilic and water-soluble polymer with low toxicity; Biotin is an enzyme co-factor, can be used for labeling protein .
|
-
- HY-P2136F
-
|
|
Apoptosis
|
Neurological Disease
Inflammation/Immunology
Cancer
|
|
Biotin-COG1410 TFA is a biotin labled COG1410 (HY-P2136). COG1410 is an apolipoprotein E-derived peptide and an apoptosis inhibitor. COG1410 exerts neuroprotective and antiinflammatory effects in a murine model of traumatic brain injury (TBI). COG1410 can be used for the research of neurological disease .
|
-
- HY-112295
-
|
|
Biochemical Assay Reagents
|
Infection
|
|
AzKTB is a capture reagent which bears a short trypsin-cleavable peptide sequence between the azide module and the TAMRA/PEG-biotin labels. AzKTB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-P1264F
-
|
|
nAChR
|
Neurological Disease
|
|
α-Bungarotoxin, FITC labeledis the FITC labelled α-Bungarotoxin (HY-P1264). α-Bungarotoxin is a competitive antagonist at nicotinic acetylcholine receptors (nAChRs) .
|
-
- HY-147206A
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-PEG-Alk (MW 1000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 1000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-147206B
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-PEG-Alk (MW 2000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 2000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-147206C
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-PEG-Alk (MW 3400) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 3400) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-147206E
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-PEG-Alk (MW 10000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 10000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-147206F
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-PEG-Alk (MW 20000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 20000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W250928C
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-PEG-azide (MW 2000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; azide, is a moderately good leaving group, can react with alkyne by Cu-catalyzation, which improve the efficiency of biotin binding targets. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-W250928D
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-PEG-azide (MW 3400) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; azide, is a moderately good leaving group, can react with alkyne by Cu-catalyzation, which improve the efficiency of biotin binding targets. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-N0324F
-
|
|
Dyes
|
|
Cholic acid-Biotin is a biotin-labeled Cholic acid (HY-N0324). Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid has orally activity .
|
-
- HY-D2353
-
|
|
Dyes
|
|
Biotin-PEG3-benzophenone is biotin-labeled Benzophenone (HY-Y0546). Benzophenone is an endogenous metabolite and a photosensitizer that has been implicated in photosensitive damage to DNA. Benzophenone causes nucleobase oxidation, formation of cyclobutane-pyrimidine dimers, single-strand breaks, DNA-protein cross-links or abasic sites, different pathologies that may occur in nucleosides, oligonucleotides or DNA .
|
-
- HY-B2227F
-
|
|
Dyes
|
|
Lactate-Biotin is the biotin labeled Lactate (HY-B2227). Lactate-Biotin is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-135641
-
|
|
Fluorescent Dyes/Probes
|
|
Biotin-probe 1 is a non-radiolabeled probe. Biotin-labeled probes can be applied to in situ hybridization .
|
-
- HY-D2355
-
|
|
Fluorescent Dyes/Probes
|
|
tris-NTA Biotin is a biotin-labeled tris-NTA. tris-NTA Biotin can be used as a reversible probe to label proteins and cell surfaces reversibly .
|
-
- HY-D1669
-
|
|
Fluorescent Dyes/Probes
|
|
Biotin-11-UTP is a Biotin-labeled uridine triphosphate (UTP), containing 11 atoms in the linker between biotin and UTP. Biotin-11-UTP can biotinylate transcribed RNA in vitro and has been widely used as labeling RNA probe . Biotin-11-UTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
| Cat. No. |
Product Name |
Type |
-
- HY-100894
-
|
|
Cell Assay Reagents
|
|
Biotin-VAD-FMK is a cell permeable, irreversible biotin-labeled caspase inhibitor, used to identify active caspases in cell lysates.
|
-
- HY-D0183
-
|
|
Enzyme Substrates
|
|
ATP-polyamine-biotin, the first cell-permeable ATP analogue, is an efficient kinase cosubstrate. ATP-polyamine-biotin promotes biotin labeling of kinase substrates in live cells .
|
-
- HY-161809
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG4-phosphorylamino-inosine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-157920
-
|
N-biotinyl-N'-[2-(N-maleimido)ethyl]piperazine
|
Biochemical Assay Reagents
|
|
Biotin-PE-maleimide (N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine) is a bulky, membrane-impermeable, sulfhydryl-containing reagent with a relatively large molecular size. Biotin-PE-maleimide can be used for biotin labeling (such as thiol groups) and detection of proteins or other biomolecules .
|
-
- HY-147207A
-
|
|
Drug Delivery
|
|
Phospholipid-PEG-Biotin (MW 2000) is a Biotin labeled phospholipid PEG derivative, can be used for modify liposome and cells surface, and pancreatic islets for cell transplantation. Phospholipid is a class of lipid containing a hydrophilic “head” and two hydrophobic “tails”; PEG is a hydrophilic and water-soluble polymer with low toxicity; Biotin is an enzyme co-factor, can be used for labeling protein .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P2609F
-
|
|
PACAP Receptor
|
Others
|
|
PACAP (1-38), amide, Biotin-labeled is a biological active peptide. (Biotin-labeled HY-P0221)
|
-
- HY-P2491
-
|
|
Fluorescent Dye
|
Cardiovascular Disease
Endocrinology
|
|
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for cardiovascular diseases research .
|
-
- HY-P1097F
-
|
|
Peptides
|
Others
|
|
Biotin-Gastrin-1, human (1-17) is a biological active peptide. (Biotin-labeled HY-P1097)
|
-
- HY-P4869
-
-
- HY-13443F
-
|
|
Peptides
|
Others
|
|
Exendin 4, biotin labeled is a biological active peptide. (Biotin labeled HY-13443)
|
-
- HY-P4078
-
|
|
Peptides
|
Others
|
|
(Arg)9 biotin labeled is a cell-permeable peptide. (Arg)9 biotin labeled can be used for drug delivery. (Arg)9 biotin labeled can traverse the plasma membrane of eukaryotic cells .
|
-
- HY-P2504
-
|
|
Syk
|
Others
|
|
Syk Kinase Peptide Substrate, Biotin labeled is a biotin-labled Syk kinase peptide substrate.
|
-
- HY-P5351
-
|
|
Peptides
|
Others
|
|
Hyaluronan-binding peptide, biotin labeled is a biological active peptide. (This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.)
|
-
- HY-P1032F
-
|
|
Endogenous Metabolite
|
Endocrinology
|
|
Biotinyl-Angiotensin I (human, mouse, rat) is biotin-labeled Angiotensin I . Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE) .
|
-
- HY-P0206F
-
|
|
Peptides
|
Others
|
|
biotin-Bradykinin is a biological active peptide. (Biotin labeled HY-P0206)
|
-
- HY-P0286F
-
|
|
Peptides
|
Others
|
|
Biotin-OVA (323-339) is a biological active peptide. (Biotin labeled HY-P0286)
|
-
- HY-P2510
-
|
|
Thyroid Hormone Receptor
|
Metabolic Disease
|
|
Parathyroid Hormone (1-34), human, biotinylated is a probe for the parathyroid hormone receptor, can be used for analyzing the interaction between parathyroid hormone and parathyroid hormone receptors in living cells and for purifying hormone-receptor complexes with affinity columns .
|
-
- HY-P2549
-
-
- HY-P2551
-
|
|
Amyloid-β
|
Neurological Disease
|
|
Biotin-β-Amyloid (17-40) is a N-terminal-labelled biotinylated amyloid-?-(1-40) peptide. β-Amyloid (17-40) is a 24-residue fragment of the Aβ protein via?post-translational processing of amyloid precursor protein (APP) .
|
-
- HY-P3844
-
-
- HY-P10620
-
|
|
Peptides
|
Others
|
|
GGGYK-Biotin is a substrate peptide designed to study the substrate specificity of Sortase A. GGGYK-Biotin can be used to develop Sortase A variants with different substrate specificities .
|
-
- HY-P1264F1
-
|
|
nAChR
|
Neurological Disease
|
|
Biotin-α-Bungarotoxin is the Biotin labelled α-Bungarotoxin (HY-P1264). α-Bungarotoxin is a competitive antagonist at nicotinic acetylcholine receptors (nAChRs) .
|
-
- HY-13948F
-
|
biotin-Ahx-Angiotensin II; biotin-Ahx-Ang II; biotin-Ahx-DRVYIHPF
|
Peptides
|
Others
|
|
Biotin-Ahx-Angiotensin II human (Biotin-Ahx-Angiotensin II; Biotin-Ahx-Ang II; Biotin-Ahx-DRVYIHPF) is a biological active peptide. (biotin labeled HY-13948)
|
-
- HY-P2546
-
|
|
Neurokinin Receptor
|
Neurological Disease
|
|
Biotin-Substance P is the biotin tagged Substance P. Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R) .
|
-
- HY-P3576
-
|
|
Fluorescent Dye
|
Neurological Disease
Cancer
|
|
Biotin-Gastrin Releasing Peptide, human is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties .
|
-
- HY-P10244F
-
|
|
Peptides
|
Infection
|
|
Biotin-YVAD-FMK is an inhibitor for vacuolar processing enzyme (VPE), with a 64% inhibition at 5 μM. Biotin-YVAD-FMK is an irreversible substrate for caspase 1 .
|
-
- HY-P10569
-
|
|
EGFR
|
Cancer
|
|
Biotin HER-2 substrate peptide is a substrate of Her4 and Her2/neu tyrosine kinase with a Km value of 60 μm for Her2/neu kinase domain .
|
-
- HY-P10566
-
|
|
BCL6
|
Cancer
|
|
BCOR(498-514), biotinylated is the minimal BCL6 binding domain with an KD value of 1.32 µM. BCOR(498-514), biotinylated blocks BCL6-mediated transcriptional repression and kills lymphoma cells .
|
-
- HY-P10372
-
|
|
Src
|
Cancer
|
|
pFYN peptide is a biotin-labled phosphorylated peptide substrate derived from FYN (a Src family kinase) .
|
-
- HY-P3616
-
|
|
GCGR
|
Metabolic Disease
|
|
Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide is a biotin labeled glucagon-like peptide-1-(7-36). Glucagon-like peptide-1-(7-36) is a gastrointestinal peptide with antidiabetogenic activity, and can increase the release of insulin .
|
-
- HY-P2136F
-
|
|
Apoptosis
|
Neurological Disease
Inflammation/Immunology
Cancer
|
|
Biotin-COG1410 TFA is a biotin labled COG1410 (HY-P2136). COG1410 is an apolipoprotein E-derived peptide and an apoptosis inhibitor. COG1410 exerts neuroprotective and antiinflammatory effects in a murine model of traumatic brain injury (TBI). COG1410 can be used for the research of neurological disease .
|
-
- HY-P1264F
-
|
|
nAChR
|
Neurological Disease
|
|
α-Bungarotoxin, FITC labeledis the FITC labelled α-Bungarotoxin (HY-P1264). α-Bungarotoxin is a competitive antagonist at nicotinic acetylcholine receptors (nAChRs) .
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-140922
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Biotin-PEG4-alkyne is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140910
-
|
|
|
Azide
PROTAC Synthesis
|
|
Biotin-PEG4-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140911
-
|
|
|
Azide
PROTAC Synthesis
|
|
Biotin-PEG6-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-127112
-
|
|
|
Alkynes
|
|
Oleic acid alkyne is oleic acid with an acetylene group. The terminal alkyne group can be used for click chemical ligation reactions. Oleic acid can be hydroxylated by a microsomal cytochrome P-450-dependent system (ω-OAH). Through click chemistry reactions, fluorescent or biotin-labeled oleic acid can be introduced to analyze its metabolism and biological activity.
|
-
- HY-147206
-
|
|
|
Alkynes
|
|
Biotin-PEG-Alk (MW 600) is a Biotin-labeled Alkyne functionalized polyethylene glycol. Biotin-PEG-Alk (MW 600) can be used to modify proteins, peptides, and oligonucleotides . Biotin-PEG-Alk (MW 600) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-139107
-
|
|
|
Azide
ADC Synthesis
|
|
Biotin-PEG4-SS-azide is a cleavable, biotin-labeled, ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Biotin-PEG4-SS-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-112295
-
|
|
|
Azide
|
|
AzKTB is a capture reagent which bears a short trypsin-cleavable peptide sequence between the azide module and the TAMRA/PEG-biotin labels. AzKTB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-147206A
-
|
|
|
Alkynes
|
|
Biotin-PEG-Alk (MW 1000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 1000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-147206B
-
|
|
|
Alkynes
|
|
Biotin-PEG-Alk (MW 2000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 2000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-147206C
-
|
|
|
Alkynes
|
|
Biotin-PEG-Alk (MW 3400) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 3400) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-147206E
-
|
|
|
Alkynes
|
|
Biotin-PEG-Alk (MW 10000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 10000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-147206F
-
|
|
|
Alkynes
|
|
Biotin-PEG-Alk (MW 20000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 20000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W250928C
-
|
|
|
Azide
|
|
Biotin-PEG-azide (MW 2000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; azide, is a moderately good leaving group, can react with alkyne by Cu-catalyzation, which improve the efficiency of biotin binding targets. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-W250928D
-
|
|
|
Azide
|
|
Biotin-PEG-azide (MW 3400) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; azide, is a moderately good leaving group, can react with alkyne by Cu-catalyzation, which improve the efficiency of biotin binding targets. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-146244A
-
|
|
|
CpG ODNs
|
|
Biotin-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. Biotin-labeled Agatolimod (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
- HY-146245A
-
|
|
|
CpG ODNs
|
|
Biotin-labeled ODN 1826 (sodium), a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. Biotin-labeled ODN 1826 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
- HY-150751A
-
|
|
|
CpG ODNs
|
|
Biotin-labeled ODN TTAGGG (sodium), a inhibitory oligonucleotide (ODN), is a TLR9, AIM2 and cGAS antagonist. Biotin-labeled ODN TTAGGG (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
- HY-150724A
-
|
|
|
CpG ODNs
|
|
Biotin-labeled ODN 1018 (sodium), an oligodeoxynucleotide, is a TLR-9 agonist. Biotin-labeled ODN 1018 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
- HY-150743A
-
|
|
|
CpG ODNs
|
|
Biotin-labeled ODN 2395 (sodium), a C class oligodeoxynucleotide, is a TLR9 agonist. Biotin-labeled ODN 2395 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
- HY-150725A
-
|
|
|
CpG ODNs
|
|
Biotin-labeled ODN 1585 (sodium) is a potent inducer of IFN and TNFα production. Biotin-labeled ODN 1585 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
- HY-150738A
-
|
|
|
CpG ODNs
|
|
Biotin-labeled ODN 2088 (sodium) is a potent TLR3, TLR7 and TLR9 inhibitor. Biotin-labeled ODN 2088 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
- HY-150726A
-
|
|
|
CpG ODNs
|
|
Biotin-labeled ODN 1668 (sodium), a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. Biotin-labeled ODN 1668 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
- HY-150741A
-
|
|
|
CpG ODNs
|
|
Biotin-labeled ODN 2216 (sodium) is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. Biotin-labeled ODN 2216 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
|
-
- HY-147207A
-
|
|
|
Pegylated Lipids
|
|
Phospholipid-PEG-Biotin (MW 2000) is a Biotin labeled phospholipid PEG derivative, can be used for modify liposome and cells surface, and pancreatic islets for cell transplantation. Phospholipid is a class of lipid containing a hydrophilic “head” and two hydrophobic “tails”; PEG is a hydrophilic and water-soluble polymer with low toxicity; Biotin is an enzyme co-factor, can be used for labeling protein .
|
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent:
