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cell-binding

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Antifolate (1) CD3 (1) Fluorescent Dye (1) Integrin (2) Nucleoside Antimetabolite/Analog (1)
By Research Areas:	Cancer (4) Inflammation/Immunology (1)
Oligonucleotides:	Aptamers (1)

6

Inhibitors & Agonists

1

Fluorescent Dye

2

Peptides

1

Inhibitory Antibodies

1

Natural
Products

1

Recombinant Proteins

1

Antibodies

1

Oligonucleotides

Targets Recommended: Penicillin-binding protein (PBP) FKBP FABP Itk Transthyretin (TTR) Ligands for Target Protein for PROTAC TOPK YB-1 NAMPT ALCAM/CD166 GDNF Receptor BCL6 GHR Tim3 BMI1 P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Gly-Arg-Gly-Asp-Ser GRGDS	Integrin	Others
Gly-Arg-Gly-Asp-Ser (GRGDS) is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin. Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC₅₀ of ～5 and ～6.5 μM

PKH 67 2 Publications Verification	Fluorescent Dye	Others
PKH67 is a fluorescent cell binding dye with green fluorescence. PKH67 can stain the cell membrane and the Ex/Em is 490/502 nm. PKH67 is often used in combination with the non-specific red fluorescent dye PKH26 (Ex/Em=551/567 nm) to label cells, detect cell proliferation in vitro, and trace cells in vitro and in vivo .

Gly-Arg-Gly-Asp-Ser TFA GRGDS TFA	Integrin	Inflammation/Immunology
Gly-Arg-Gly-Asp-Ser (TFA) is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin . Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC₅₀ of ∼5 and ∼6.5 μM .

Denopterin Pteroylglutamic acid	Antifolate Nucleoside Antimetabolite/Analog	Cancer
Denopterin is a dihydrofolate reductase (DHFR) inhibitor and an antifolate agent. Denopterin is an antimetabolite that has toxic effects on cells and can be used for cancer .

CL2 Linker	ADC Linker	Cancer
CL2 Linker is a cleavableADC linker. CL2-SN-38 and CL2A-SN-38 are equivalent in agent substitution (~6), cell binding (K_d ~1.2 nM), cytotoxicity (IC₅₀ ~2.2 nM), and serum stability in vitro (t_1/2 ~20 hours) .

Tidutamab XmAb-18087	CD3	Cancer
Tidutamab (XmAb-18087) is a humanized and affinity-optimized bispecific antibody (bsAb) targeting SSTR2 binding domain and *T-cell binding* domain (CD3)*. Tidutamab possesses a full Fc domain to maintain long serum half-life.Tidutamab eliminates SSTR+ tumor cells* by stimulating redirected T cellmediated cytotoxicity (RTcC) .

Cat. No.	Product Name	Type

PKH 67 2 Publications Verification	Fluorescent Dyes/Probes
PKH67 is a fluorescent cell binding dye with green fluorescence. PKH67 can stain the cell membrane and the Ex/Em is 490/502 nm. PKH67 is often used in combination with the non-specific red fluorescent dye PKH26 (Ex/Em=551/567 nm) to label cells, detect cell proliferation in vitro, and trace cells in vitro and in vivo .

Cat. No.	Product Name	Target	Research Area

Gly-Arg-Gly-Asp-Ser GRGDS	Integrin	Others
Gly-Arg-Gly-Asp-Ser (GRGDS) is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin. Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC₅₀ of ～5 and ～6.5 μM

Gly-Arg-Gly-Asp-Ser TFA GRGDS TFA	Integrin	Inflammation/Immunology
Gly-Arg-Gly-Asp-Ser (TFA) is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin . Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC₅₀ of ∼5 and ∼6.5 μM .

Cat. No.	Product Name	Target	Research Area

Tidutamab XmAb-18087	CD3	Cancer
Tidutamab (XmAb-18087) is a humanized and affinity-optimized bispecific antibody (bsAb) targeting SSTR2 binding domain and *T-cell binding* domain (CD3)*. Tidutamab possesses a full Fc domain to maintain long serum half-life.Tidutamab eliminates SSTR+ tumor cells* by stimulating redirected T cellmediated cytotoxicity (RTcC) .

Cat. No.	Product Name	Category	Target	Chemical Structure

Tidutamab XmAb-18087	Classification of Application Fields Disease Research Fields Cancer	CD3
Tidutamab (XmAb-18087) is a humanized and affinity-optimized bispecific antibody (bsAb) targeting SSTR2 binding domain and *T-cell binding* domain (CD3)*. Tidutamab possesses a full Fc domain to maintain long serum half-life.Tidutamab eliminates SSTR+ tumor cells* by stimulating redirected T cellmediated cytotoxicity (RTcC) .

Cat. No.	Compare	Product Name	Species	Source

	IBSP Protein, Human (His-SUMO) BNSP; Bone sialoprotein 2; Bone sialoprotein II; BSP; BSP II; BSPII; cell binding sialoprotein; cell-binding sialoprotein; IBSP; Integrin binding sialoprotein; Integrin-binding sialoprotein; SIAL_HUMAN; SPII	Human	E. coli
	The IBSP protein has a strong affinity for hydroxyapatite and plays a crucial role in mineralized matrix formation, indicating its overall nature in this regard. Its tight binding suggests an important role in cell-matrix interactions, particularly in promoting RGD-dependent cell attachment. IBSP Protein, Human (His-SUMO) is the recombinant human-derived IBSP protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of IBSP Protein, Human (His-SUMO) is 153 a.a., with molecular weight of ~40 kDa.

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	BNSP Antibody integrin binding sialoprotein; BSP; BNSP; SP-II; BSP-II; IBSP; Bone sialoprotein II; cell binding sialoprotein; Integrin binding sialoprotein; SIAL_HUMAN; Bone sialoprotein 2; cell-binding sialoprotein; Integrin-binding sialoprotein.	WB, IHC-P, IHC-F, ICC/IF, ELISA	Mouse, Rat
	IBSP Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 35 kDa, targeting to IBSP. It can be used for WB, IHC-P assays with tag free, in the background of Human, Mouse.

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Cat. No.	Product Name		Classification

sgc8c aptamer sodium		Aptamers
sgc8c aptamer sodium is an aptamer that specifically targets the human protein tyrosine kinase PTK-7, which is mainly expressed on cervical cancer HeLa cells. Binding of sgc8c aptamer sodium to PTK-7 induces the assembly of nanotags on the cell surface, resulting in strong fluorescence and SERS signals. Specific to cervical cancer cells .

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