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Results for "

oxidoreductase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Cytotoxin (1) AMPK (1) Antibiotic (1) Apoptosis (1) Bacterial (1) Biochemical Assay Reagents (3) Caspase (1) Cytochrome P450 (3) DNA Alkylator/Crosslinker (2) Drug Metabolite (1) Endogenous Metabolite (6) Fluorescent Dye (1) Isotope-Labeled Compounds (1) Lactate Dehydrogenase (1) Microtubule/Tubulin (2) Mitochondrial Metabolism (4) Parasite (5) PDHK (1) Pyroptosis (1) Reactive Oxygen Species (1) STAT (1) URAT1 (1) Xanthine Oxidase (11)
By Research Areas:	Cancer (12) Cardiovascular Disease (3) Endocrinology (1) Infection (7) Inflammation/Immunology (1) Metabolic Disease (19) Neurological Disease (3)

By Targets:

ADC Cytotoxin (1)

AMPK (1)

Antibiotic (1)

Apoptosis (1)

Bacterial (1)

Biochemical Assay Reagents (3)

Caspase (1)

Cytochrome P450 (3)

DNA Alkylator/Crosslinker (2)

Drug Metabolite (1)

Endogenous Metabolite (6)

Fluorescent Dye (1)

Isotope-Labeled Compounds (1)

Lactate Dehydrogenase (1)

Microtubule/Tubulin (2)

Mitochondrial Metabolism (4)

Parasite (5)

PDHK (1)

Pyroptosis (1)

Reactive Oxygen Species (1)

STAT (1)

URAT1 (1)

Xanthine Oxidase (11)

By Research Areas:

Cancer (12)

Cardiovascular Disease (3)

Endocrinology (1)

Infection (7)

Inflammation/Immunology (1)

Metabolic Disease (19)

Neurological Disease (3)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-151974

*Xanthine oxidoreductase-IN-4*	Xanthine Oxidase	Metabolic Disease
Xanthine oxidoreductase-IN-4 is an orally active *xanthine oxidoreductase* (XOR)** inhibitor. Xanthine oxidoreductase-IN-4 has inhibitory activity against XOR with an IC₅₀ value of 29.3 nM. Xanthine oxidoreductase-IN-4 can be used for the research of hyperuricemia .

HY-151975

*Xanthine oxidoreductase-IN-5*	Xanthine Oxidase	Metabolic Disease
Xanthine oxidoreductase-IN-5 is an orally active *xanthine oxidoreductase* (XOR) inhibitor, with an IC₅₀** of 55 nM. Xanthine oxidoreductase-IN-5 can be used for the research of acute hyperuricemia .

HY-151973

*Xanthine oxidoreductase-IN-3*	Xanthine Oxidase	Metabolic Disease
Xanthine oxidoreductase-IN-3 is an orally active *xanthine oxidoreductase* (XOR) inhibitor, with an IC₅₀** of 26.3 nM. Xanthine oxidoreductase-IN-3 can be used for the research of acute hyperuricemia .

HY-146297

*Xanthine oxidoreductase-IN-2*	Xanthine Oxidase	Metabolic Disease
Xanthine oxidoreductase-IN-2 (Compound IVa) is a xanthine oxidoreductase (XOR) inhibitor with the IC₅₀ of 7.2 nM. Xanthine oxidoreductase-IN-2 shows hypouricemic effects in mice .

HY-146296

*Xanthine oxidoreductase-IN-1*	Xanthine Oxidase	Metabolic Disease
The compound is a xanthine oxidoreductase (XOR) inhibitor with high inhibitory concentration, and the value of ic₅₀ is 7.0 nm.

HY-149769

CP-506	Others	Cancer
CP-506 (compound 26) is an anticancer compound and a substrate for nitroreductase and CYP oxidoreductases. CP-506 has anticancer activity .

HY-N10191

Hydroaurantiogliocladin	Others	Metabolic Disease
Hydroaurantiogliocladin is a quinol. Hydroaurantiogliocladin can be used as substrate for the quinol-cytochrome c oxidoreductase activity (beef heart enzyme) .

HY-P2807F

Lactate Dehydrogenase (LDH), Bovine Heart LAD, LD, L-LDH, (S)-Lactate: NAD+ oxidoreductase	Others	Others
Lactate Dehydrogenase (LDH), Bovine Heart (LAD, LD, L-LDH, (S)-Lactate: NAD+ oxidoreductase) is a biological material or organic compound that can be used in life science research .

HY-W012927

4-Hydroxy-5-methylfuran-3(2H)-one Chicory furaneol	Biochemical Assay Reagents	Others
4-Hydroxy-5-methylfuran-3(2H)-one (Chicory furaneol) can be used to assay oxidoreductase activity. 4-Hydroxy-5-methylfuran-3(2H)-one is a kind of biological materials or organic compounds that are widely used in life science research .

HY-125027

Isobutyl-deoxynyboquinone IB-DNQ	Others	Cancer
Isobutyl-deoxynyboquinone (IB-DNQ) is a selective substrate for NAD(P)H:quinone oxidoreductase (NQO1). Isobutyl-deoxynyboquinone can be used for the research of anticancer .

HY-144439

HTS07545	Others	Cardiovascular Disease
HTS07545 is a potent *sulfide:quinone oxidoreductase* (SQOR) inhibitor with an IC₅₀** of 30 nM. HTS07545 decrease the rate of breakdown of hydrogen sulfide (H2S). HTS07545 can be used for heart failure research .

HY-E70375

Fructosyl-peptide oxidase (FPOX-CE) Fructosyl-peptide: oxygen oxidoreductase	Others	Others
Fructosyl-peptide oxidase (FPOX-CE) (Fructosyl-peptide: oxygen oxidoreductase) is an enzyme that catalyzes the oxidation of glycopeptides. Fructosyl-peptide oxidase (FPOX-CE) shows high activity against small molecule glycated peptides, but no activity is detected against the glycated hexapeptide standard fVHLTPE used in the study. Fructosyl-peptide oxidase (FPOX-CE) can be used in the study of diabetes monitoring .

HY-157744

Coumarin–quinone conjugate	Others	Cancer
Coumarin–quinone conjugate is a fluorescent substrate for NADH:ubiquinone oxidoreductases which consists of a coumarin fluorophore and a ubiquinone analog. Coumarin–quinone conjugate can be used to measure the kinetic parameters of AIFM2/FSP1 for researches such as ferroptosis .

HY-135024

Phenylacetyl CoA Phenylacetyl Coenzyme A	Endogenous Metabolite	Metabolic Disease
Phenylacetyl CoA is an acceptor oxidoreductase. Phenylacetyl CoA is a membrane-bound molybdenum–iron–sulfur enzyme involved in anaerobic metabolism of phenylalanine in the denitrifying bacterium Thauera aromatica .

HY-W007584

2,4-Dimethoxybenzyl alcohol	Others	Others
2,4-Dimethoxybenzyl alcohol, an aromatic alcohol, is a substrate of glucose-methanol-choline (GMC) oxidoreductase. GMC oxidoreductase displays the characteristics of an aryl-alcohol oxidase .

HY-14572

PR-104A SN 27858	DNA Alkylator/Crosslinker Drug Metabolite	Cancer
PR-104A (SN 27858) is the alcohol metabolite of phosphate proagent PR-104. PR-104A is a hypoxia-selective DNA cross-linking agent/DNA-damaging agent and cytotoxin. Antitumor Activity . PR-104A is metabolized under hypoxia by the 1-electron NADPH:cytochrome P450 oxidoreductase. PR-104A can be used for the research of relapsed/refractory T-lineage acute lymphoblastic leukemia (T-ALL) .

HY-118588

Diminutol	Microtubule/Tubulin	Others
Diminutol is an inhibitor for NADP-dependent quinone oxidoreductase (NQO1), that is involved in microtubule morphogenesis and cell devision .

HY-116433

Nequinate	Parasite Xanthine Oxidase	Infection Metabolic Disease
Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections . Nequinate inhibits xanthine oxidoreductase (XOD) activity .

HY-14669

Niraxostat Y-700; Piraxostat	Xanthine Oxidase	Metabolic Disease
Niraxostat (Y-700; Piraxostat) is an orally active xanthine oxidoreductase (XOR) inhibitor used in the study of hyperuricemia and other diseases in which XOR may be involved .

HY-N0645

Dicoumarol 5+ Cited Publications Dicumarol	PDHK	Cancer
Dicoumarol is an inhibitor of both *NAD(P)H:quinone oxidoreductase* 1 (NQO1) and PDK1 with IC₅₀**s of 0.37 and 19.42 μM, respectively.

HY-125999

EPI-589	Others	Neurological Disease
EPI-589, a quinone derivative, is a safe and well tolerated *oxidoreductase enzyme* inhibitor. EPI-589 has the potential for the treatment of amyotrophic lateral sclerosis (ALS) .

HY-P2755

Xanthine oxidase, Microorganism XO; XOD	Reactive Oxygen Species	Inflammation/Immunology Endocrinology
Xanthine oxidase, Microorganism (XO) is a xanthine oxidoreductase enzyme that generates reactive oxygen species (ROS), catalyzes the oxidation of hypoxanthine to xanthine, and further catalyzes the oxidation of xanthine to uric acid .

HY-103667

2-HBA 3 Publications Verification	Caspase	Cancer
2-HBA is a potent inducer of *NAD(P)H:quinone acceptor oxidoreductase* 1 (NQO1) which can also activate caspase-3 and caspase-10**.

HY-135024A

Phenylacetyl CoA lithium Phenylacetyl Coenzyme A lithium	Endogenous Metabolite	Metabolic Disease
Phenylacetyl CoA lithium (Phenylacetyl Coenzyme A lithium) is an acceptor oxidoreductase. Phenylacetyl CoA is a membrane-bound molybdenum–iron–sulfur enzyme involved in anaerobic metabolism of phenylalanine in the denitrifying bacterium Thauera aromatica .

HY-156136

5-n-Heptyl-6-hydroxy-4,7-dioxobenzothiazole	Biochemical Assay Reagents	Others
5-n-Heptyl-6-hydroxy-4,7-dioxobenzothiazole is a competitive Q_o site inhibitor of the cytochrome bc 1 complex (cytochrome c oxidoreductase) from Saccharomyces cerevisiae .

HY-B0825A

Fenpyroximate	Parasite Mitochondrial Metabolism	Infection
Fenpyroximate is an acaricide and insecticide against many mites and insect pests of agricultural crops and ornamentals. Fenpyroximate is also a strong inhibitor of *bovine heart mitochondrial NADH-ubiquinone oxidoreductase* (complex I)**, binds to the ND5 subunit .

HY-P2743

Choline oxidase	Biochemical Assay Reagents	Others
Choline oxidase (EC 1.1.3.17) catalyzes the oxidation of choline to glycine betaine via betaine aldehyde in glycine betaine biosynthesis and betaine acts as an osmolyte. Choline oxidase has potential in enzymatic betaine production .

HY-N5018

Nepodin Musizin	Parasite AMPK	Infection
Nepodin (Musizin) is a *quinone oxidoreductase* (PfNDH2)** inhibitor isolate from Rumex crispus .Nepodin (Musizin) stimulates the translocation of GLUT4 to the plasma membrane by activation of AMPK .Nepodin (Musizin) has antidiabetic and antimalarial activities.

HY-P2897

D-Lactate dehydrogenase, Microorganism D-LDH	Lactate Dehydrogenase	Others
D-Lactate dehydrogenase, Microorganism (D-LDH) is an oxidoreductase that uses NAD ⁺ or NADP ⁺ as an acceptor and acts on the donor CH-OH group, and can catalyze the oxidation of D-lactate to pyruvate. D-Lactate dehydrogenase widely exists in bacteria and fungi, and is often used in biochemical research .

HY-141552

FC9402	Others	Cardiovascular Disease
FC9402 is a potent and selective sulfide quinone oxidoreductase (SQOR) inhibitor extracted from patent WO 2020/146636 A1. FC9402 attenuates TAC-induced cardiomyocyte hypertrophy and left ventricle (LV) fibrosis. FC9402 can be used for cardiovascular regulation .

HY-146036

NADH-IN-1	Endogenous Metabolite	Metabolic Disease
NADH-IN-1 has NADH:ubiquinone oxidoreductase inhibitory activity with an IC₅₀ value of 27 μM. NADH-IN-1 can effectively stimulate glucose uptake in vitro. NADH-IN-1 is readily metabolised by the liver. NADH-IN-1 can be used for researching diabetes .

HY-W783829

(2E)-Hexenoyl-CoA Hex-2-trans-enoyl-CoA	Others	Metabolic Disease
(2E)-Hexenoyl-CoA (Hex-2-trans-enoyl-CoA) is an intermediate in fatty acid metabolism. (2E)-Hexenoyl-CoA is the substrate of the enzymes enoyl-coenzyme A reductase, acyl-CoA oxidase,? acyl-CoA dehydrogenase, long-chain-acyl-CoA dehydrogenase and Oxidoreductases .

HY-14874

Topiroxostat 5 Publications Verification FYX-051	Xanthine Oxidase Cytochrome P450	Metabolic Disease
Topiroxostat (FYX-051) is a potent and orally active *xanthine oxidoreductase* (XOR) inhibitor with an IC₅₀ value of 5.3 nM and a K_i value of 5.7 nM. Topiroxostat exhibits weak CYP3A4**-inhibitory activity (18.6%). Topiroxostat has the potential for hyperuricemia treatment .

HY-15924

Thiazolyl Blue Maximum Cited Publications 107 Publications Verification MTT; Thiazolyl Blue Tetrazolium bromide; Methylthiazolyldiphenyl-tetrazolium bromide	Fluorescent Dye	Others
Thiazolyl Blue (MTT) is a cell-permeable and positively charged tetrazolium dye that is used to detect reductive metabolism in cells. Thiazolyl Blue is taken up by cells through the plasma membrane and then reduced to formazan by intracellular NAD (P) H-oxidoreductases. Thiazolyl Blue is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis .

HY-145820

Tubulin inhibitor 14	Apoptosis Microtubule/Tubulin	Cancer
Tubulin inhibitor 14 is a potent *NQO2 (quinone oxidoreductase* 2) inhibitor with an IC₅₀** of 1.0 μM. Tubulin inhibitor 14 also inhibits tubulin polymerization and the formation of endothelial cell capillary-like tubes. Tubulin inhibitor 14 is a microtubule-destabilizing agent with potential tumor-selectivity and antiangiogenic and vascular disrupting features .

HY-W016628

L-Gulono-1,4-lactone L-Gulonolactone	Endogenous Metabolite	Metabolic Disease
L-Gulono-1,4-lactone is a substrate of L-gulono-1,4-lactone oxidoreductase, which catalyzes the last step of the biosynthesis of L-ascorbic (Vatamin) C. In other words, L-Gulono-1,4-lactone is a direct precursor of vitamin C in animals, in plants and in some protists.

HY-P2902

Glucose oxidase 2 Publications Verification	Endogenous Metabolite	Cancer
Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O₂) to produce hydrogen peroxide (H₂O₂) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation .

HY-120338

RYL-552	Mitochondrial Metabolism Parasite	Infection
RYL-552, a mitochondrial electron transport chain (ETC) inhibitor, is a *P. falciparum NADH dehydrogenase 2 (PfNDH2)* inhibtor .

HY-14874S

Topiroxostat-d4 FYX-051-d₄	Isotope-Labeled Compounds Xanthine Oxidase Cytochrome P450	Metabolic Disease
Topiroxostat-d₄ is deuterium labeled Topiroxostat. Topiroxostat (FYX-051) is a potent and orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 value of 5.3 nM and a Ki value of 5.7 nM. Topiroxostat exhibits weak CYP3A4-inhibitory activity (18.6%). Topiroxostat has the potential for hyperuricemia treatment[1][2].

HY-P3186

Glucose dehydrogenase, recombinant Microorganisms	Endogenous Metabolite	Metabolic Disease
Glucose dehydrogenase, recombinant Microorganisms is a oxidoreductase. Glucose dehydrogenase (GDH) catalyzes the oxidation of β-D-glucose to β-D-glucono-1,5-lactone with simultaneous reduction of the cofactor NADP ⁺ to NADPH or, to a lesser extent, NAD ⁺ to NADH. Glucose dehydrogenase (GDH) accepts both NAD ⁺ and NADP ⁺ as cofactors and can be used for the regeneration of NADH and NADPH .

HY-150971

ICy-Q	Pyroptosis	Cancer
ICy-Q is a quinone oxidoreductase 1 (NQO-1)-activated near-infrared (NIR) reagent which can react with NQO-1 to release the reduction product ICy-OH. ICy-OH selectively induces pancreatic cancer cell death through the pyroptosis pathway. ICy-Q can be used as an effective tool for rapid and accurate diagnosis of intraoperative pathological sections .

HY-148706

STAT3-IN-17	STAT	Infection Cancer
STAT3-IN-17 is a moderate STAT3 inhibitor (IC₅₀=0.7 μM; HEK-Blue IL-6), with antiproliferative activity in HeLa cells. STAT3-IN-17 has good pharmacokinetic characteristics. STAT3-IN-17 also inhibits pyruvate-ferredoxin oxidoreductase (PFOR), and inhibits Helicobacter pylori .

HY-14874R

Topiroxostat (Standard)	Xanthine Oxidase Cytochrome P450	Metabolic Disease
Topiroxostat (Standard) is the analytical standard of Topiroxostat. This product is intended for research and analytical applications. Topiroxostat (FYX-051) is a potent and orally active *xanthine oxidoreductase* (XOR) inhibitor with an IC₅₀ value of 5.3 nM and a K_i value of 5.7 nM. Topiroxostat exhibits weak CYP3A4**-inhibitory activity (18.6%). Topiroxostat has the potential for hyperuricemia treatment .

HY-129278

Lunarine	Parasite	Infection Cardiovascular Disease Neurological Disease
Lunarine is an alkaloid, which can be isolated from the seeds of kale (Lunaria annua). Lunarine lowers the blood pressure, stimulates small intestinal motility, inhibits spontaneous contractions of uterus and nervous system, and exhibits an acute toxicity with LD₅₀ of 62.3 mg/kg in dogs and rabbits. Lunarine exhibits antiparasitic activity through a competitive inhibition of protozoan oxidoreductase trypanothione reductase (TryR) with K_i of 304 μM .

HY-128895

KL1333 1 Publications Verification	Mitochondrial Metabolism	Metabolic Disease
KL1333, a derivative of β-lapachone, is an orally available NAD+ modulator. KL1333 reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL1333 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. KL1333 protects against Cisplatin-induced ototoxicity in mouse cochlear cultures .

HY-13543

Tretazicar CB 1954	DNA Alkylator/Crosslinker	Cancer
Tretazicar (CB 1954), an antitumor proagent, is highly selective against the Walker 256 rat tumour line. Tretazicar is enzymatically activated to generate a bifunctional agent, which can form DNA-DNA interstrand cross-links. Tretazicar in rat cells involves the reduction of its 4-nitro group to a 4-hydroxylamine by the enzyme NAD(P)H:quinone oxidoreductase 1 (NQO1) .

HY-161523

XOR/URAT1-IN-1	Xanthine Oxidase URAT1	Metabolic Disease
XOR/URAT1-IN-1 (Compound II15) is a dual inhibitor for xanthine oxidoreductase (XOR) and uric acid transporter 1 (URAT1), with IC₅₀ of 6 nM and 12.9 μM. XOR/URAT1-IN-1 lowers the levels of uric acid in Potassium oxonate (HY-17511)/Hypoxanthine (HY-N0091)-induced acute hyperuricemia mouse model .

HY-114936

Piericidin A 1 Publications Verification AR-054	Bacterial ADC Cytotoxin Antibiotic Mitochondrial Metabolism	Infection Neurological Disease Cancer
Piericidin A (AR-054) is a natural mitochondrial *NADH-ubiquinone oxidoreductase* (complex I) inhibitor. Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase. Piericidin A is also a potential quorum-sensing** inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca). Piericidin A is an ADC cytotoxin and has anti-bacterial, anticancer, insecticidal activity .

Cat. No.	Product Name	Type

HY-15924

Thiazolyl Blue 105+ Cited Publications MTT; Thiazolyl Blue Tetrazolium bromide; Methylthiazolyldiphenyl-tetrazolium bromide	Chromogenic Substrates
Thiazolyl Blue (MTT) is a cell-permeable and positively charged tetrazolium dye that is used to detect reductive metabolism in cells. Thiazolyl Blue is taken up by cells through the plasma membrane and then reduced to formazan by intracellular NAD (P) H-oxidoreductases. Thiazolyl Blue is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis .

Cat. No.	Product Name	Type

HY-W012927

4-Hydroxy-5-methylfuran-3(2H)-one Chicory furaneol	Biochemical Assay Reagents
4-Hydroxy-5-methylfuran-3(2H)-one (Chicory furaneol) can be used to assay oxidoreductase activity. 4-Hydroxy-5-methylfuran-3(2H)-one is a kind of biological materials or organic compounds that are widely used in life science research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0645

Dicoumarol 5+ Cited Publications Dicumarol	Structural Classification Melilotus officinalis (L.) Pall. Classification of Application Fields Leguminosae Source classification Coumarins Phenylpropanoids Plants Disease Research Fields Biological Pesticide Research Cancer Agricultural Research	PDHK
Dicoumarol is an inhibitor of both *NAD(P)H:quinone oxidoreductase* 1 (NQO1) and PDK1 with IC₅₀**s of 0.37 and 19.42 μM, respectively.

HY-N5018

Nepodin Musizin	Rumex crispus Linn. Infection Structural Classification Classification of Application Fields Polygonaceae Source classification Phenols Polyphenols Rumex japonicus Houtt. Plants Disease Research Fields	Parasite AMPK
Nepodin (Musizin) is a *quinone oxidoreductase* (PfNDH2)** inhibitor isolate from Rumex crispus .Nepodin (Musizin) stimulates the translocation of GLUT4 to the plasma membrane by activation of AMPK .Nepodin (Musizin) has antidiabetic and antimalarial activities.

HY-N10191

Hydroaurantiogliocladin	Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Metabolic Disease Disease Research Fields	Others
Hydroaurantiogliocladin is a quinol. Hydroaurantiogliocladin can be used as substrate for the quinol-cytochrome c oxidoreductase activity (beef heart enzyme) .

HY-135024

Phenylacetyl CoA Phenylacetyl Coenzyme A	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Phenylacetyl CoA is an acceptor oxidoreductase. Phenylacetyl CoA is a membrane-bound molybdenum–iron–sulfur enzyme involved in anaerobic metabolism of phenylalanine in the denitrifying bacterium Thauera aromatica .

HY-135024A

Phenylacetyl CoA lithium Phenylacetyl Coenzyme A lithium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Phenylacetyl CoA lithium (Phenylacetyl Coenzyme A lithium) is an acceptor oxidoreductase. Phenylacetyl CoA is a membrane-bound molybdenum–iron–sulfur enzyme involved in anaerobic metabolism of phenylalanine in the denitrifying bacterium Thauera aromatica .

HY-146036

NADH-IN-1	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NADH-IN-1 has NADH:ubiquinone oxidoreductase inhibitory activity with an IC₅₀ value of 27 μM. NADH-IN-1 can effectively stimulate glucose uptake in vitro. NADH-IN-1 is readily metabolised by the liver. NADH-IN-1 can be used for researching diabetes .

HY-W016628

L-Gulono-1,4-lactone L-Gulonolactone	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides	Endogenous Metabolite
L-Gulono-1,4-lactone is a substrate of L-gulono-1,4-lactone oxidoreductase, which catalyzes the last step of the biosynthesis of L-ascorbic (Vatamin) C. In other words, L-Gulono-1,4-lactone is a direct precursor of vitamin C in animals, in plants and in some protists.

HY-129278

Lunarine	Structural Classification Alkaloids Lunaria annua L. Other Alkaloids Source classification Plants Brassicaceae	Parasite
Lunarine is an alkaloid, which can be isolated from the seeds of kale (Lunaria annua). Lunarine lowers the blood pressure, stimulates small intestinal motility, inhibits spontaneous contractions of uterus and nervous system, and exhibits an acute toxicity with LD₅₀ of 62.3 mg/kg in dogs and rabbits. Lunarine exhibits antiparasitic activity through a competitive inhibition of protozoan oxidoreductase trypanothione reductase (TryR) with K_i of 304 μM .

HY-114936

Piericidin A 1 Publications Verification AR-054	Structural Classification Neurological Disease Classification of Application Fields Source classification Anti-parasitic Antibacterial Disease Research Other Antibiotics Infection Microorganisms Antibiotics Anticancer Disease Research Fields	Bacterial ADC Cytotoxin Antibiotic Mitochondrial Metabolism
Piericidin A (AR-054) is a natural mitochondrial *NADH-ubiquinone oxidoreductase* (complex I) inhibitor. Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase. Piericidin A is also a potential quorum-sensing** inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca). Piericidin A is an ADC cytotoxin and has anti-bacterial, anticancer, insecticidal activity .

Species:	Human (4) Mouse (2)
Tag:	His (7) SUMO (1) Tag Free (1)
Source:	HEK293 (2) E. coli (6)

Cat. No.	Compare	Product Name	Species	Source

HY-P7659

	BDH2 Protein, Human (His) rHuBDH2, His; 3-Hydroxybutyrate Dehydrogenase Type 2; oxidoreductase UCPA; BDH2	Human	E. coli
	BDH2 Protein, Human (His) expresses in E. coli with a His tag. BDH2 is a cytosolic-type 2-hydroxybutyrate dehydrogenase and has a physiological role in the utilization of cytosolic ketone bodies, which can subsequently enter mitochondria and the tricarboxylic acid cycle.

HY-P702175

	MDO Protein, Mycobacterium sp. Methanol:N; N-dimethyl-4-nitrosoaniline oxidoreductase; MDO; Methanol dehydrogenase (nicotinoprotein); Methanol:NDMA oxidoreductase	Others	E. coli
	MDO (methanol dehydrogenase) is responsible for oxidizing methanol to produce formaldehyde. Although the in vivo electron acceptor remains unidentified, in vitro experiments indicate that N,N-dimethyl-4-nitrosaniline (NDMA) can serve as a suitable electron acceptor and is subsequently reduced to 4-(hydroxyamino) -N,N-Dimethylaniline. MDO Protein, Mycobacterium sp. is the recombinant MDO protein, expressed by E. coli , with tag free. The total length of MDO Protein, Mycobacterium sp. is 423 a.a., .

HY-P702176

	MDO Protein, Mycobacterium sp. (His) Methanol:N; N-dimethyl-4-nitrosoaniline oxidoreductase; MDO; Methanol dehydrogenase (nicotinoprotein); Methanol:NDMA oxidoreductase	Others	E. coli
	MDO (methanol dehydrogenase) is responsible for oxidizing methanol to produce formaldehyde. Although the in vivo electron acceptor remains unidentified, in vitro experiments indicate that N,N-dimethyl-4-nitrosaniline (NDMA) can serve as a suitable electron acceptor and is subsequently reduced to 4-(hydroxyamino) -N,N-Dimethylaniline. MDO Protein, Mycobacterium sp. (His) is the recombinant MDO protein, expressed by E. coli , with N-6*His labeled tag. The total length of MDO Protein, Mycobacterium sp. (His) is 423 a.a., .

HY-P70955

	GMPR Protein, Human (HEK293, His) GMP Reductase 1; Guanosine 5' -Monophosphate oxidoreductase 1; Guanosine Monophosphate Reductase 1; GMPR; GMPR1	Human	HEK293
	GMP reductase 1 (GMPR1) catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. GMPR1 functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. GMPR1 contributes to non-shivering thermogenesis while promoting the progression of Alzheimer's disease. GMPR Protein, Human (HEK293, His) is the recombinant human-derived GMPR protein, expressed by HEK293 , with C-6*His labeled tag. The total length of GMPR Protein, Human (HEK293, His) is 345 a.a., with molecular weight of ~40.0 kDa.

HY-P74632

	PIG3 Protein, Human (His) Quinone oxidoreductase PIG3; TP53I3; PIG3	Human	E. coli
	PIG3 is a key player in cellular processes, functioning as an enzyme that catalyzes NADPH-dependent quinone reduction. It exhibits moderate enzymatic activity towards β-naphthoquinone, with the para -quinone isomer (1,2-β-naphthoquinone) compared to the para -isomer (1,4-β-naphthoquinone). Obvious preference. PIG3 Protein, Human (His) is the recombinant human-derived PIG3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of PIG3 Protein, Human (His) is 332 a.a., with molecular weight of ~37.5 kDa.

HY-P76947

	GFOD2 Protein, Mouse (HEK293, His) Glucose-fructose oxidoreductase domain-containing protein 2; GFOD2	Mouse	HEK293
	GFOD2 Protein actively promotes matrix assembly, playing a pivotal role in orchestrating the extracellular matrix's formation. Its significance in cellular architecture highlights its nuanced functions, warranting further exploration to understand the detailed mechanisms governing its regulatory roles. GFOD2's involvement suggests potential contributions to diverse cellular processes and biological pathways. GFOD2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived GFOD2 protein, expressed by HEK293 , with C-His labeled tag. The total length of GFOD2 Protein, Mouse (HEK293, His) is 360 a.a., with molecular weight of ~41.2 KDa.

HY-P72169

	DCT Protein, Mouse (His-SUMO) Dct; Tyrp-2; Tyrp2; L-dopachrome tautomerase; DCT; DT; EC 5.3.3.12; DOPAchrome conversion factor; DOPAchrome isomerase; DOPAchrome oxidoreductase; L-dopachrome Delta-isomerase; SLATY locus protein; Tyrosinase-related protein 2; TRP-2; TRP2	Mouse	E. coli
	DCT (Dopachrome tautomerase) is pivotal in melanin biosynthesis, catalyzing the conversion of L-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid (DHICA), a critical step in melanin synthesis. DCT's enzymatic activity is integral to the complex processes governing melanin production, emphasizing its role in skin pigmentation and the regulation of melanin-related functions. DCT Protein, Mouse (His-SUMO) is the recombinant mouse-derived DCT protein, expressed by E. coli , with N-10*His, N-SUMO labeled tag. The total length of DCT Protein, Mouse (His-SUMO) is 449 a.a., with molecular weight of ~69.7 kDa.

HY-P72076

	ALOX12 Protein, Human (His) 1 Publications Verification 12 LOX; 12S; lipoxygenase ; 12-lipoxygenase; 12LO; 12S LOX; 12S-lipoxygenase; 12S-LOX; 12S-type; Alox12; Arachidonate 12 lipoxygenase; Arachidonate 12 lipoxygenase, 12S type; Arachidonate 12-lipoxygenase; Arachidonate 12-oxidoreductase; Lipoxin synthase 12-LO; LOG12; LOX12_HUMAN; P-12LO; Platelet 12-LOX; Platelet type lipoxygenase 12 ; platelet-type 12-lipoxygenase; Platelet-type lipoxygenase 12	Human	E. coli
	ALOX12 Protein, Human (His) is a recombinant ALOX12 protein with a His tag. ALOX12 encodes arachidonic acid 12-lipoxygenase that acts on different polyunsaturated fatty acid substrates to produce biologically active lipid mediators including eicosanes and lipoxins.

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Cat. No.	Product Name	Chemical Structure

HY-14874S

Topiroxostat-d4
Topiroxostat-d₄ is deuterium labeled Topiroxostat. Topiroxostat (FYX-051) is a potent and orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 value of 5.3 nM and a Ki value of 5.7 nM. Topiroxostat exhibits weak CYP3A4-inhibitory activity (18.6%). Topiroxostat has the potential for hyperuricemia treatment[1][2].

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82790

	NDUFS1 Antibody (YA2535) NDUFS1; NADH-ubiquinone oxidoreductase 75 kDa subunit; mitochondrial; Complex I-75kD; CI-75kD	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	NDUFS1 Antibody (YA2535) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2535), targeting NDUFS1, with a predicted molecular weight of 79 kDa (observed band size: 75 kDa). NDUFS1 Antibody (YA2535) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

HY-P81601

	NDUFS3 Antibody (YA1346) NDUFS3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3; mitochondrial; Complex I-30kD; CI-30kD; NADH-ubiquinone oxidoreductase 30 kDa subunit	WB	Human, Mouse
	NDUFS3 Antibody (YA1346) is a biotin-conjugated non-conjugated IgG antibody, targeting NDUFS3, with a predicted molecular weight of 30 kDa (observed band size: 26 kDa). NDUFS3 Antibody (YA1346) can be used for WB experiment in human, mouse background.

HY-P82212

	Xanthine Oxidase Antibody (YA1957) Xanthine dehydrogenase; Xanthine oxidase; Xanthine oxidoreductase; XD; XDH; xdha; XO; xor	WB, IHC-P	Human, Mouse, Rat
	Xanthine Oxidase Antibody (YA1957) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1957), targeting Xanthine Oxidase, with a predicted molecular weight of 146 kDa (observed band size: 146 kDa). Xanthine Oxidase Antibody (YA1957) can be used for WB, IHC-P experiment in human, mouse, rat background.

HY-P82344

	MT ND1 Antibody (YA2089) MT-ND1; MTND1; NADH1; ND1; NADH-ubiquinone oxidoreductase chain 1; NADH dehydrogenase subunit 1	WB	Human, Mouse, Rat
	MT ND1 Antibody (YA2089) is a biotin-conjugated non-conjugated IgG antibody, targeting MT ND1, with a predicted molecular weight of 36 kDa (observed band size: 36 kDa). MT ND1 Antibody (YA2089) can be used for WB experiment in human, mouse, rat background.

HY-P81585

	NDUFB10 Antibody (YA1330) NDUFB10; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10; Complex I-PDSW; CI-PDSW; NADH-ubiquinone oxidoreductase PDSW subunit	WB, IHC-F, IHC-P, ICC/IF, IP	Human
	NDUFB10 Antibody (YA1330) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1330), targeting NDUFB10, with a predicted molecular weight of 21 kDa (observed band size: 21 kDa). NDUFB10 Antibody (YA1330) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human background.

HY-P81595

	NDUFB9 Antibody (YA1340) NDUFB9; LYRM3; UQOR22; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9; Complex I-B22; CI-B22; LYR motif-containing protein 3; NADH-ubiquinone oxidoreductase B22 subunit	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	NDUFB9 Antibody (YA1340) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1340), targeting NDUFB9, with a predicted molecular weight of 22 kDa (observed band size: 22 kDa). NDUFB9 Antibody (YA1340) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human, mouse, rat background.

HY-P81196

	HSD3B1 Antibody 3BHS1_HUMAN; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I; 3-beta-HSD I; 3-beta-hydroxy-5-ene steroid dehydrogenase 1; 3-beta-hydroxy-Delta(5)-steroid dehydrogenase 1; EC:1.1.1.145; 3-beta-hydroxysteroid 3-dehydrogenase 1; EC:1.1.1.270; Delta-5-3-ketosteroid isomerase; Dihydrotestosterone oxidoreductase. EC:1.1.1.210; Steroid Delta-isomerase 1; EC:5.3.3.1; Trophoblast antigen FDO161G; 3BH; HSDB3A	WB, ELISA, IHC-P, IHC-F, ICC/IF	Mouse, Rat
	HSD3B1 Antibody is an unconjugated, approximately 41 kDa, rabbit-derived, anti-HSD3B1 polyclonal antibody. HSD3B1 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in mouse, rat, and predicted: human, dog, cow, horse background without labeling.