2. Apoptosis Immunology/Inflammation
  3. Pyroptosis
  4. ICy-Q

ICy-Q is a quinone oxidoreductase 1 (NQO-1)-activated near-infrared (NIR) reagent which can react with NQO-1 to release the reduction product ICy-OH. ICy-OH selectively induces pancreatic cancer cell death through the pyroptosis pathway. ICy-Q can be used as an effective tool for rapid and accurate diagnosis of intraoperative pathological sections.

For research use only. We do not sell to patients.

ICy-Q Chemical Structure

ICy-Q Chemical Structure

CAS No. : 2863682-83-9

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Description

ICy-Q is a quinone oxidoreductase 1 (NQO-1)-activated near-infrared (NIR) reagent which can react with NQO-1 to release the reduction product ICy-OH. ICy-OH selectively induces pancreatic cancer cell death through the pyroptosis pathway. ICy-Q can be used as an effective tool for rapid and accurate diagnosis of intraoperative pathological sections[1].

Molecular Weight

988.73

Formula

C48H50I2N2O5
CAS No.
SMILES

CC1=C(C(C(C(C)(C)CC(N(C2=CC=C(C=C2)COC3=CC4=C(C=C5CCCC(/C=C/C6=[N+](C7=C(C6(C)C)C=C(C=C7)I)C)=C5O4)C=C3)C)=O)=C(C1=O)C)=O)C.[I-]
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ICy-Q Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ICy-Q2863682-83-9PyroptosisNQO-1NIRICy-OHpyroptosisanticancerpancreatic cancerInhibitorinhibitorinhibit

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