DCT Protein, Mouse (His-SUMO)

DCT (Dopachrome tautomerase) is pivotal in melanin biosynthesis, catalyzing the conversion of L-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid (DHICA), a critical step in melanin synthesis. DCT's enzymatic activity is integral to the complex processes governing melanin production, emphasizing its role in skin pigmentation and the regulation of melanin-related functions. DCT Protein, Mouse (His-SUMO) is the recombinant mouse-derived DCT protein, expressed by E. coli , with N-10*His, N-SUMO labeled tag. The total length of DCT Protein, Mouse (His-SUMO) is 449 a.a., with molecular weight of ~69.7 kDa.

DCT (Dopachrome tautomerase) is integral to melanin biosynthesis, a process crucial for pigmentation. Functioning as an enzyme, DCT plays a key role in the conversion of L-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid (DHICA), a pivotal step in the melanin synthesis pathway. The catalytic activity of DCT contributes to the intricate biochemical processes underlying the production of melanin, highlighting its significance in determining skin pigmentation and the regulation of melanin-related biological functions.

Mouse

E. coli

N-10*His;N-SUMO

P29812 (Q24-S472)

13190  [NCBI]

QFPRVCMTLDGVLNKECCPPLGPEATNICGFLEGRGQCAEVQTDTRPWSGPYILRNQDDREQWPRKFFNRTCKCTGNFAGYNCGGCKFGWTGPDCNRKKPAILRRNIHSLTAQEREQFLGALDLAKKSIHPDYVITTQHWLGLLGPNGTQPQIANCSVYDFFVWLHYYSVRDTLLGPGRPYKAIDFSHQGPAFVTWHRYHLLWLERELQRLTGNESFALPYWNFATGKNECDVCTDELLGAARQDDPTLISRNSRFSTWEIVCDSLDDYNRRVTLCNGTYEGLLRRNKVGRNNEKLPTLKNVQDCLSLQKFDSPPFFQNSTFSFRNALEGFDKADGTLDSQVMNLHNLAHSFLNGTNALPHSAANDPVFVVLHSFTDAIFDEWLKRNNPSTDAWPQELAPIGHNRMYNMVPFFPPVTNEELFLTAEQLGYNYAVDLSEEEAPVWSTTLS

Approximately 69.7 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.