2. Metabolic Enzyme/Protease
  3. Xanthine Oxidase
  4. Xanthine oxidoreductase-IN-4

Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor. Xanthine oxidoreductase-IN-4 has inhibitory activity against XOR with an IC50 value of 29.3 nM. Xanthine oxidoreductase-IN-4 can be used for the research of hyperuricemia.

For research use only. We do not sell to patients.

Xanthine oxidoreductase-IN-4 Chemical Structure

Xanthine oxidoreductase-IN-4 Chemical Structure

CAS No. : 1026587-58-5

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Xanthine oxidoreductase-IN-4 Related Antibodies

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Description

Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor. Xanthine oxidoreductase-IN-4 has inhibitory activity against XOR with an IC50 value of 29.3 nM. Xanthine oxidoreductase-IN-4 can be used for the research of hyperuricemia[1].

IC50 & Target

IC50: 29.3 nM (XOR)[1]
In Vitro

Xanthine oxidoreductase-IN-4 (Compound IIIc) has inhibitory activity against XOR with an IC50 value of 29.3 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Xanthine oxidoreductase-IN-4 Related Antibodies
In Vivo

Xanthine oxidoreductase-IN-4 (Compound IIIc) (oral; 5 mg/kg) shows a significant hypouricemia effect in a potassium oxazinate/hypoxanthine-induced model of acute hyperuricemia[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mice acute hyperuricemia model[1]
Dosage: 5 mg/kg
Administration: Oral
Result: Reduced serum levels of uric acid significantly from 4 h after administration.
Molecular Weight

309.32

Formula

C16H15N5O2
CAS No.
SMILES

CCOC1=CC=C(C=C1)NC(C2=CC=C(C=C2)C3=NN=NN3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Xanthine oxidoreductase-IN-4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Xanthine oxidoreductase-IN-41026587-58-5Xanthine OxidaseXOxanthine oxidoreductase (XOR)HypouricemicPhenyl-tetrazoleInhibitorinhibitorinhibit

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