2. Metabolic Enzyme/Protease
  3. Xanthine Oxidase
  4. Xanthine oxidoreductase-IN-4

Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor. Xanthine oxidoreductase-IN-4 has inhibitory activity against XOR with an IC50 value of 29.3 nM. Xanthine oxidoreductase-IN-4 can be used for the research of hyperuricemia.

For research use only. We do not sell to patients.

Xanthine oxidoreductase-IN-4 Chemical Structure

Xanthine oxidoreductase-IN-4 Chemical Structure

CAS No. : 1026587-58-5

Size Price Stock Quantity
1 mg USD 121 Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
5 mg USD 270 Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
10 mg USD 407 Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
25 mg USD 693 Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 mg USD 1053 Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 mg   Get quote  
200 mg   Get quote  

Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor. Xanthine oxidoreductase-IN-4 has inhibitory activity against XOR with an IC50 value of 29.3 nM. Xanthine oxidoreductase-IN-4 can be used for the research of hyperuricemia[1].

IC50 & Target

IC50: 29.3 nM (XOR)[1]
In Vitro

Xanthine oxidoreductase-IN-4 (Compound IIIc) has inhibitory activity against XOR with an IC50 value of 29.3 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo

Xanthine oxidoreductase-IN-4 (Compound IIIc) (oral; 5 mg/kg) shows a significant hypouricemia effect in a potassium oxazinate/hypoxanthine-induced model of acute hyperuricemia[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mice acute hyperuricemia model[1]
Dosage: 5 mg/kg
Administration: Oral
Result: Reduced serum levels of uric acid significantly from 4 h after administration.
Molecular Weight

309.32

Formula

C16H15N5O2
CAS No.
SMILES

CCOC1=CC=C(C=C1)NC(C2=CC=C(C=C2)C3=NN=NN3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Xanthine oxidoreductase-IN-4 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Xanthine oxidoreductase-IN-41026587-58-5Xanthine OxidaseXOxanthine oxidoreductase (XOR)HypouricemicPhenyl-tetrazoleInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Xanthine oxidoreductase-IN-4
Cat. No.:
HY-151974
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (0 KB) Français - FR (0 KB) Deutsch - DE (0 KB) Norwegian - NO (0 KB) Español - ES (0 KB) Swedish - SV (0 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.