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Results for "

transglutaminase (Tgase)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (3) Biochemical Assay Reagents (4) Caspase (3) Glutaminase (4)
By Research Areas:	Cancer (4) Metabolic Disease (1) Neurological Disease (1)

Inhibitors & Agonists

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: Transglutaminase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-124476

Cystamine	Caspase Glutaminase Apoptosis	Cancer
Cystamine is the disulfide form of the free thiol, cysteamine. Cystamine is an orally active **transglutaminase (Tgase) inhibitor. Cystamine also has inhibition activity for caspase-3 with an IC₅₀** value of 23.6 μM. Cystamine can be used for the research of severals diseases including Huntington's disease (HD) .

HY-W020050

Cystamine dihydrochloride	Caspase Glutaminase Apoptosis	Neurological Disease Cancer
Cystamine (dihydrochloride) is the disulfide form of the free thiol, cysteamine. Cystamine is an orally active **transglutaminase (Tgase) inhibitor. Cystamine also has inhibition activity for caspase-3 with an IC₅₀** value of 23.6 μM. Cystamine can be used for the research of severals diseases including Huntington's disease (HD) .

HY-12337

GK921 4 Publications Verification	Glutaminase	Cancer
GK921 is a transglutaminase 2 (TGase) inhibitor with an IC₅₀ of 7.71 μM for human recombinant TGase 2.

HY-E70453

Human prostate transglutaminase Prostate transglutaminase; TG4; TGase 4	Biochemical Assay Reagents	Metabolic Disease
Human prostate transglutaminase (TG4; TGase 4) is an enzyme that mediates the transfer of acyl groups from glutamine residues in proteins or peptides to primary amines and belongs to the prostate transglutaminase protein family. Human prostate transglutaminase forms an ε-(γ-glutamyl)lysine bond between proteins by transferring the acyl group of a peptide-bound glutamine residue to the primary amino group of a peptide-bound lysine residue .

HY-E70437

Guinea pig liver transglutaminase Tissue-type transglutaminase; TG2; TGase 2	Biochemical Assay Reagents	Others
Guinea pig liver transglutaminase (Tissue-type transglutaminase) is an exoenzyme. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture .

HY-E70439

Human epidermal transglutaminase TG3; TGase 3	Biochemical Assay Reagents	Others
Human epidermal transglutaminase (TG3) is a transferase. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture .

HY-E70436

Human keratinocyte transglutaminase TG1; TGase 1	Biochemical Assay Reagents	Others
Human keratinocyte transglutaminase (TG1) is a transglutaminase. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture .

HY-W020050S

Cystamine-d8 dihydrochloride	Apoptosis Caspase Glutaminase	Cancer
Cystamine-d₈ (dihydrochloride） is the deuterium labeled Cystamine (dihydrochloride）[1]. Cystamine (dihydrochloride) is the disulfide form of the free thiol, cysteamine. Cystamine is an orally active transglutaminase (Tgase) inhibitor. Cystamine also has inhibition activity for caspase-3 with an IC50 value of 23.6 μM. Cystamine can be used for the research of severals diseases including Huntington's disease (HD)[2][3][4].

Species:	Human (2) Mouse (3)
Tag:	His (5)
Source:	HEK293 (2) Sf9 insect cells (2) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P78361

	TGM2/Transglutaminase 2 Protein, Mouse (His) Heart G alpha(h); TGM2; tTG; tTgase; transglutaminase C; TG(C); TGC; TGase C; transglutaminase H; TGase II; transglutaminase-2; TG2; G-ALPHA-h; GNAH; HEL-S-45; C polypeptide; TGase-2; TGase-H; TGCGNAH	Mouse	E. coli
	The TGM2/transglutaminase 2 protein is a calcium-dependent acyltransferase involved in bone development, angiogenesis, wound healing, and apoptosis.TGM2 is also involved in neurotransmission-independent actions and serves as a signal transducer in α-1 adrenergic receptor-mediated pathways.TGM2/Transglutaminase 2 Protein, Mouse (His) is the recombinant mouse-derived TGM2/Transglutaminase 2 protein, expressed by E.coli , with N-His labeled tag.

HY-P77257

	Transglutaminase 3/TGM3 Protein, Human (sf9, His) Protein-glutamine gamma-glutamyltransferase E; transglutaminase E; TGase-3	Human	Sf9 insect cells
	Transglutaminase 3 (TGM3) serves as a catalyst in the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in diverse proteins, alongside mediating the conjugation of polyamines to proteins. This enzymatic activity plays a crucial role in the intricate process of cornified envelope (CE) formation, a specialized structure comprising covalent cross-links of proteins beneath the plasma membrane in fully differentiated keratinocytes. TGM3 is actively involved in cross-linking small proline-rich proteins (SPRR1 and SPRR2) and loricrin (LOR) to create small interchain oligomers. These oligomers are subsequently cross-linked by TGM1 onto the developing CE scaffold, contributing to the structural integrity of this vital component. Notably, TGM3's involvement extends to hair follicles, where it participates in cross-linking structural proteins to fortify the inner root sheath. Transglutaminase 3/TGM3 Protein, Human (sf9, His) is the recombinant human-derived Transglutaminase 3/TGM3 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of Transglutaminase 3/TGM3 Protein, Human (sf9, His) is 692 a.a., with molecular weight of ~70 kDa.

HY-P71132

	TGM2/Transglutaminase 2 Protein, Mouse (HEK293, His) Protein-glutamine gamma-glutamyltransferase 2; Tgm2; Tissue transglutaminase; transglutaminase C; TGase-2	Mouse	HEK293
	The TGM2/transglutaminase 2 protein is a calcium-dependent acyltransferase involved in bone development, angiogenesis, wound healing, and apoptosis.TGM2 is also involved in neurotransmission-independent actions and serves as a signal transducer in α-1 adrenergic receptor-mediated pathways.TGM2/Transglutaminase 2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived TGM2/Transglutaminase 2 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71132A

	TGM2/Transglutaminase 2 Protein, Mouse (HEK293, C-His) Protein-glutamine gamma-glutamyltransferase 2; Tgm2; Tissue transglutaminase; transglutaminase C; TGase-2	Mouse	HEK293
	The TGM2/transglutaminase 2 protein is a calcium-dependent acyltransferase involved in bone development, angiogenesis, wound healing, and apoptosis.TGM2 is also involved in neurotransmission-independent actions and serves as a signal transducer in α-1 adrenergic receptor-mediated pathways.TGM2/Transglutaminase 2 Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived TGM2/Transglutaminase 2 protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P76114Y

	TGM2/Transglutaminase 2 Protein, Human (sf9, His, solution) Protein-glutamine gamma-glutamyltransferase 2; transglutaminase C; TGase-2	Human	Sf9 insect cells
	In summary, TGM2 is a multifunctional enzyme that plays crucial roles in various cellular processes. It acts as a protein-glutamine gamma-glutamyl transferase, mediating the cross-linking of proteins involved in cellular functions. TGM2/Transglutaminase 2 Protein, Human (sf9, His, solution) is the recombinant human-derived TGM2/Transglutaminase 2, expressed by Sf9 insect cells , with N-His labeled tag. ,

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Cat. No.	Product Name	Chemical Structure

HY-W020050S

Cystamine-d8 dihydrochloride
Cystamine-d₈ (dihydrochloride） is the deuterium labeled Cystamine (dihydrochloride）[1]. Cystamine (dihydrochloride) is the disulfide form of the free thiol, cysteamine. Cystamine is an orally active transglutaminase (Tgase) inhibitor. Cystamine also has inhibition activity for caspase-3 with an IC50 value of 23.6 μM. Cystamine can be used for the research of severals diseases including Huntington's disease (HD)[2][3][4].

Cystamine-d8 dihydrochloride

Cystamine-d₈ (dihydrochloride） is the deuterium labeled Cystamine (dihydrochloride）[1]. Cystamine (dihydrochloride) is the disulfide form of the free thiol, cysteamine. Cystamine is an orally active transglutaminase (Tgase) inhibitor. Cystamine also has inhibition activity for caspase-3 with an IC50 value of 23.6 μM. Cystamine can be used for the research of severals diseases including Huntington's disease (HD)[2][3][4].

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81886

	Factor XIIIa Antibody (YA1631) Coagulation factor XIIIa; F13A; F13a1; Fibrin stabilizing factor; A subunit; Fibrinoligase; TGase; transglutaminase A chain	WB, IHC-P	Human
	Factor XIIIa Antibody (YA1631) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1631), targeting Factor XIIIa, with a predicted molecular weight of 83 kDa (observed band size: 83 kDa). Factor XIIIa Antibody (YA1631) can be used for WB, IHC-P experiment in human background.

HY-P82510

	Transglutaminase 2 Antibody (YA2255) TGM2; Protein-glutamine gamma-glutamyltransferase 2; Tissue transglutaminase; transglutaminase C; TG(C); TGC; TGase C; transglutaminase H; TGase H; transglutaminase-2; TGase-2	WB, IHC-P, IP	Human, Mouse, Rat
	Transglutaminase 2 Antibody (YA2255) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2255), targeting Transglutaminase 2, with a predicted molecular weight of 77 kDa (observed band size: 77 kDa). Transglutaminase 2 Antibody (YA2255) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.

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