1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. GABA Receptor
  3. Fengabine

Fengabine is a GABAergic antidepressant agent. Fengabine can be used for the research of depression.

For research use only. We do not sell to patients.

Fengabine Chemical Structure

Fengabine Chemical Structure

CAS No. : 80018-06-0

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Description

Fengabine is a GABAergic antidepressant agent. Fengabine can be used for the research of depression[1].

In Vivo

Fengabine (50 mg/kg; i.p.; 2 days) prevents completely the learned helplessness induced by the unavoidable shock[1].
Fengabine (150 mg/kg; i.p) decreases the percentage of time spent. Fengabine (25~50 mg/kg; i.p.) reverses the deficit in learning the step-down avoidance task[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Rats[1]
Dosage: 50 mg/kg
Administration: I.p.
Result: Prevented completely the learned helplessness induced by the unavoidable shock.
Molecular Weight

322.23

Formula

C17H17Cl2NO

CAS No.
SMILES

OC1=CC=C(C=C1/C(C2=CC=CC=C2Cl)=N\CCCC)Cl

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Fengabine
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HY-123478
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