Fluazinam impurity 1 

Fluazinam impurity 1 is an impurity of Fluazinam with antifungal activity. Fluazinam impurity 1 is active against Sphaerotheca fuliginea, Pyricularia oryzae and Rhizoctonia solani^[1].

Fungal^[1]

Quantitative structure-activity relationships (QSAR) analyses of fungicidal activity of Fluazinam impurity 1 against Sphaerotheca fuliginea, Pyricularia oryzae and Rhizoctonia solani are carried out and the results are compared. In the case of S. fuliginea, a usual QSAR equation with Hammett's electronic parameter (sigma-m) and hydrophobicity π is obtained, suggesting that the uncoupling mechanism might be involved in the mode of action. In the cases of P. oryzae and R. solani, QSAR equations are consisted of sigma-m, pi and the activity rank against Botrytis cinerea as independent variables,indicating both of uncoupling and SH-inhibition are working in the action mechanism^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

465.09

C₁₃H₄Cl₂F₆N₄O₄

169327-87-1

Solid

White to off-white

FC(C1=CN=C(NC2=C(C(F)(F)F)C=C([N+]([O-])=O)C(Cl)=C2[N+]([O-])=O)C(Cl)=C1)(F)F

Room temperature in continental US; may vary elsewhere.

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

• [1]. Toshio Akagi, et al. Quantitative structure-activity relationships of fluazinam and related fungicidal N-phenylpyridinamines : preventive activity against Botrytis cinerea. Nippon Noyaku Gakkaishi (1995), 20(3), 279-90.