2. Gene
  3. ERBB3 - erb-b2 receptor tyrosine kinase 3 Gene

ERBB3 - erb-b2 receptor tyrosine kinase 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Sus scrofa
Gene ID: 100525045 | Gene type: protein coding

About ERBB3

Primary_assembly 5: 21,474,475-21,495,038 forward strand.Sscrofa11.1:CM000816.5

This gene has 3 transcripts (splice variants), 280 orthologues and 52 paralogues. Biased expression in liver (RPKM 32.3), kidney (RPKM 29.2) and 4 other tissues.

ERBB3 Products(1)

mRNA Protein Name
XM_021091799.1 XP_020947458.1 receptor tyrosine-protein kinase erbB-3

ERBB3 Protein Structure

Recep_L_domain

Recep_L_domain: pfam01030 (55 - 166)

Furin-like

Furin-like: pfam00757 (178 - 328)

Recep_L_domain

Recep_L_domain: pfam01030 (352 - 473)

GF_recep_IV

GF_recep_IV: pfam14843 (498 - 629)

TM_ErbB3

TM_ErbB3: cd12095 (637 - 675)

PTK_HER3

PTK_HER3: cd05111 (700 - 978)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1338 a.a.
Protein Preferred Names Protein Names

receptor tyrosine-protein kinase erbB-3

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-118998 TX2-121-1 Inhibitor / Phase 3
HY-13050 Sapitinib Inhibitor 99.93% Phase 2
Inhibitory Antibodies (6)
Cat. No. Product Name Effect
Purity Phase
HY-P99275 Patritumab Inhibitor 98.95% Phase 3
HY-P99268 Seribantumab ≥95.0% Phase 2
HY-P99866 Duligotuzumab 97.93% Phase 2
HY-P99672 Istiratumab Inhibitor / Phase 2
HY-P99304 Lumretuzumab Inhibitor ≥99.0% Phase 1
HY-P99461 Barecetamab Inhibitor 97.96% Phase 1
Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100848 TX1-85-1 Inhibitor 98.04% Unkown
HY-18609 PD158780 Inhibitor 99.56% Unkown
HY-W006886 Fmoc-(R)-2-(7-octenyl)Ala-OH 98.85% Unkown
HY-13050A Sapitinib fumarate Inhibitor / Unkown
HY-RS04469 ERBB3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04470 Erbb3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04471 Erbb3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-164548 WK88-1 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ERBB3 NCBI NCBI:2065
Mus musculus ERBB3 NCBI NCBI:13867
Rattus norvegicus ERBB3 NCBI NCBI:29496
Macaca mulatta ERBB3 NCBI NCBI:711407