2. Gene
  3. ERBB3 - erb-b2 receptor tyrosine kinase 3 Gene

ERBB3 - erb-b2 receptor tyrosine kinase 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Macaca mulatta
Gene ID: 711407 | Gene type: protein coding

About ERBB3

Primary_assembly 11: 55,641,371-55,673,299 forward strand.Mmul_10:CM014346.1

This gene has 6 transcripts (splice variants), 280 orthologues and 53 paralogues.

ERBB3 Products(2)

mRNA Protein Name
XM_015151940.2 XP_015007426.2 receptor tyrosine-protein kinase erbB-3 isoform X1
XM_028829604.1 XP_028685437.1 receptor tyrosine-protein kinase erbB-3 isoform X2

ERBB3 Protein Structure

Recep_L_domain

Recep_L_domain: pfam01030 (55 - 166)

Furin-like

Furin-like: pfam00757 (174 - 328)

Recep_L_domain

Recep_L_domain: pfam01030 (352 - 473)

GF_recep_IV

GF_recep_IV: pfam14843 (498 - 629)

TM_ErbB3

TM_ErbB3: cd12095 (637 - 675)

PTK_HER3

PTK_HER3: cd05111 (700 - 978)

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  • 1200
  • 1342 a.a.
Protein Preferred Names Protein Names

receptor tyrosine-protein kinase erbB-3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3

Recombinant ERBB3 Proteins

Cat. No. Product Name Accession Purity
HY-P76967 HER3 Protein, Rhesus Macaque (HEK293) XP_001113953.2 (S20-T643) ≥95%
HY-P76968 HER3 Protein, Rhesus Macaque (HEK293, Fc) XP_001113953.2 (S20-T643) ≥95%
HY-P76969 HER3 Protein, Rhesus Macaque (HEK293, His) XP_001113953.2 (S20-T643) ≥95%

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-13050 Sapitinib Inhibitor 99.93% Phase 2
Inhibitory Antibodies (6)
Cat. No. Product Name Effect
Purity Phase
HY-P99275 Patritumab Inhibitor 98.95% Phase 3
HY-P99268 Seribantumab ≥95.0% Phase 2
HY-P99866 Duligotuzumab 97.93% Phase 2
HY-P99672 Istiratumab Inhibitor / Phase 2
HY-P99304 Lumretuzumab Inhibitor ≥99.0% Phase 1
HY-P99461 Barecetamab Inhibitor 97.96% Phase 1
Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100848 TX1-85-1 Inhibitor 98.04% Unkown
HY-18609 PD158780 Inhibitor 99.56% Unkown
HY-W006886 Fmoc-(R)-2-(7-octenyl)Ala-OH 98.85% Unkown
HY-118998 TX2-121-1 Inhibitor / Unkown
HY-13050A Sapitinib fumarate Inhibitor / Unkown
HY-RS04469 ERBB3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04470 Erbb3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04471 Erbb3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-164548 WK88-1 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ERBB3 NCBI NCBI:2065
Mus musculus ERBB3 NCBI NCBI:13867
Rattus norvegicus ERBB3 NCBI NCBI:29496