2. Gene
  3. TMPRSS11B - transmembrane serine protease 11B Gene

TMPRSS11B - transmembrane serine protease 11B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as HATL5

Gene ID: 132724 | Gene type: protein coding

About TMPRSS11B

This gene has 3 transcripts (splice variants), 487 orthologues and 17 paralogues. Restricted expression toward esophagus (RPKM 184.2).

Summary

Enables serine-type peptidase activity. Predicted to be involved in proteolysis. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMPRSS11B Products(1)

mRNA Protein Name
NM_182502.3 NP_872308.2 transmembrane protease serine 11B
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables serine-type peptidase activity IDA
IDA: Inferred from direct assay
24498351 GOA
Cellular Component GO Annotation Evidence Reference Source
located in plasma membrane IDA
IDA: Inferred from direct assay
24498351 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMPRSS11B Protein Structure

SEA

SEA: SEA domain (43 - 137)

Trypsin

Trypsin: Trypsin (185 - 410)

  • 0
  • 100
  • 200
  • 300
  • 416 a.a.
Protein Preferred Names Protein Names

transmembrane protease serine 11B

airway trypsin-like protease 5

Recombinant TMPRSS11B Proteins

Cat. No. Product Name Accession Purity
HY-P70869 TMPRSS11B Protein, Human (HEK293, His) Q86T26 (L39-L416) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14764 TMPRSS11B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta TMPRSS11B VGNC VGNC:107205
Mus musculus TMPRSS11B MGD MGI:2442893
Rattus norvegicus TMPRSS11B RGD RGD:1303278
Others TMPRSS11B NCBI