DPF3 - double PHD fingers 3 Gene

Homo sapiens

Also known as CERD4; BAF45C; SMARCG3

Gene ID: 8110 | Gene type: protein coding

About DPF3

Cytogenetic location: 14q24.2 Genomic coordinates (GRCh38): 14:72,609,034-72,894,101 (from NCBI)

This gene has 14 transcripts (splice variants), 208 orthologues and 9 paralogues. Biased expression in ovary (RPKM 2.9), heart (RPKM 2.2) and 11 other tissues.

Summary

This gene encodes a member of the D4 protein family. The encoded protein is a transcription regulator that binds acetylated histones and is a component of the BAF chromatin remodeling complex. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

DPF3 Products(4)

mRNA	Protein	Name
NM_001280542.3	NP_001267471.1	zinc finger protein DPF3 isoform 2
NM_001280543.2	NP_001267472.1	zinc finger protein DPF3 isoform 3
NM_001280544.2	NP_001267473.1	zinc finger protein DPF3 isoform 4
NM_012074.5	NP_036206.3	zinc finger protein DPF3 isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32459350	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DPF3 Protein Structure

Requiem_N

PHD

0
100
200
300
378 a.a.

Protein Preferred Names

Protein Names

zinc finger protein DPF3

BRG1-associated factor 45C

Related Diseases

Diseases

Alias

Melanomatosis

Atrial Septal Defect 9

ASD9	Atrial Heart Septal Defect 9
Septal Defect, Atrial, Type 9

Tetralogy Of Fallot

TOF	Fallot Tetralogy
Ventricular Septal Defect With Pulmonary Stenosis Or Atresia, Dextraposition Of Aorta, And Hypertrophy Of Right Ventricle	Tetrad Of Fallot
Fallot Tetrad	Fallot Disease
Fallot Complex	Subpulmonic Stenosis, Ventricular Septal Defect, Overriding Aorta, And Right Ventricular Hypertrophy
Interventricular Septal Defect With Dextroposition Of Aorta, Pulmonary Stenosis And Hypertrophy Of Right Ventricle	Interventricular Septal Defect, In Tetralogy Of Fallot
Ventricular Septal Defect With Obstructed Right Ventricular Outflow	Tof - [Tetralogy Of Fallot]
Pulmonary Atresia With Ventricular Septal Defect [Fallot Type]	Pulmonary Atresia, Ventricular Septal Defect And Mapcas
Pulmonary Atresia With Ventricular Septal Defect And Systemic-To-Pulmonary Collateral Arteries [Fallot Type]

Hirschsprung Disease 1

Hirschsprung Disease	Aganglionic Megacolon
Hscr	Hirschsprung'S Disease
Congenital Megacolon	Congenital Intestinal Aganglionosis
Colonic Aganglionosis	Hirschsprung Disease, Susceptibility To, 1
Hirschsprung Disease, Protection Against	HSCR1
Mgc	Pelvirectal Achalasia
Total Intestinal Aganglionosis	Megacolon, Aganglionic
Macrocolon	Hscr 1
Hirschsprung Disease Type 1	Hirschsprung Disease, Type 1
Congenital Dilatation Of Colon	Aganglionosis
Congenital Aganglionic Megacolon	Aganglionosis Of Colon
Bowel Aganglionosis	Colon Aganglionosis
Hirschsprung Megacolon

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03951	DPF3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	DPF3	VGNC	VGNC:99198
Bos taurus	DPF3	VGNC	VGNC:28177
Felis catus	DPF3	VGNC	VGNC:61595
Mus musculus	DPF3	MGD	MGI:1917377
Rattus norvegicus	DPF3	RGD	RGD:1309052
Canis familiaris	DPF3	VGNC	VGNC:50524

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