2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. Inakalant

Inakalant is an atrial specific potassium channel blocker with antiarrhythmic activity. Inakalant works by selectively blocking potassium channels in heart cells, thereby prolongs the action potential duration (APD) of cardiomyocytes and increases the effective refractory period of the atria and ventricles, which helps to terminate and prevent the occurrence of arrhythmias such as atrial fibrillation (AF). Inakalant can be used in the study of arrhythmia and cardiac electrophysiology.

For research use only. We do not sell to patients.

Inakalant Chemical Structure

Inakalant Chemical Structure

CAS No. : 335619-18-6

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Description

Inakalant is an atrial specific potassium channel blocker with antiarrhythmic activity. Inakalant works by selectively blocking potassium channels in heart cells, thereby prolongs the action potential duration (APD) of cardiomyocytes and increases the effective refractory period of the atria and ventricles, which helps to terminate and prevent the occurrence of arrhythmias such as atrial fibrillation (AF). Inakalant can be used in the study of arrhythmia and cardiac electrophysiology[1].

Molecular Weight

446.54

Formula

C23H34N4O5
CAS No.
SMILES

N#CC(C=C1)=CC=C1OC[C@@H](O)CN2CC3OC(CN(C3)CCNC(OC(C)(C)C)=O)C2
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Inakalant Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Inakalant335619-18-6Potassium ChannelKcsABlockersarrhythmiasaction potentialscardiac electrophysiologypotassium channelsInhibitorinhibitorinhibit

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