2. Academic Validation
  3. [Suc-Phe-Leu-Phe-SBzl--a new substrate for functional study of Escherichia coli ATP-dependent Lon-proteinase and its modified forms]

[Suc-Phe-Leu-Phe-SBzl--a new substrate for functional study of Escherichia coli ATP-dependent Lon-proteinase and its modified forms]

  • Bioorg Khim. 1998 Aug;24(8):638-40.
E E Mel'nikov 1,  K B Tsirul'nikov,  F S Rasulova,  L M Ginodman,  T V Rotanova
Affiliations

Affiliation

  • 1 Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
PMID: 9784881
Abstract

A new efficient substrate, Suc-Phe-Leu-Phe-SBzl, was proposed for studying the function of the Escherichia coli ATP-dependent Lon protease and its modified forms. The kinetic parameters of hydrolysis of the substrate were determined. The esterase activity of protease Lon was found to be nucleotide-regulated.

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