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MTSEA hydrobromide is a sulfhydryl-reactive compound that modifies free cysteine residues to produce a positively charged side chain approximately the size of lysine.

For research use only. We do not sell to patients.

MTSEA hydrobromide Chemical Structure

MTSEA hydrobromide Chemical Structure

CAS No. : 16599-33-0

Size Price Stock Quantity
10 mg In-stock
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100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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  • Biological Activity

  • Purity & Documentation

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Description

MTSEA hydrobromide is a sulfhydryl-reactive compound that modifies free cysteine residues to produce a positively charged side chain approximately the size of lysine[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
154 μM
Compound: ACS 42
Antiproliferative activity against human A549 cells after 3 days
Antiproliferative activity against human A549 cells after 3 days
[PMID: 18294844]
In Vitro

Cys modification by MTSEA reduces susceptibility to Cd activation of receptors with A8C or L10C substitutions[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

236.15

Formula

C3H10BrNO2S2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CS(=O)(SCCN)=O.Br

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (211.73 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2346 mL 21.1730 mL 42.3460 mL
5 mM 0.8469 mL 4.2346 mL 8.4692 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.2346 mL 21.1730 mL 42.3460 mL 105.8649 mL
5 mM 0.8469 mL 4.2346 mL 8.4692 mL 21.1730 mL
10 mM 0.4235 mL 2.1173 mL 4.2346 mL 10.5865 mL
15 mM 0.2823 mL 1.4115 mL 2.8231 mL 7.0577 mL
20 mM 0.2117 mL 1.0586 mL 2.1173 mL 5.2932 mL
25 mM 0.1694 mL 0.8469 mL 1.6938 mL 4.2346 mL
30 mM 0.1412 mL 0.7058 mL 1.4115 mL 3.5288 mL
40 mM 0.1059 mL 0.5293 mL 1.0586 mL 2.6466 mL
50 mM 0.0847 mL 0.4235 mL 0.8469 mL 2.1173 mL
60 mM 0.0706 mL 0.3529 mL 0.7058 mL 1.7644 mL
80 mM 0.0529 mL 0.2647 mL 0.5293 mL 1.3233 mL
100 mM 0.0423 mL 0.2117 mL 0.4235 mL 1.0586 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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MTSEA hydrobromide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
MTSEA hydrobromide
Cat. No.:
HY-120128
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