2. Anti-infection Metabolic Enzyme/Protease
  3. Fungal Fatty Acid Synthase (FASN)
  4. NPD6433

NPD6433 is a triazenyl indole with broad-spectrum activity against all screening fungal strains. NPD6433 targets the enoyl reductase domain of fatty acid synthase 1 (Fas1), covalently inhibiting its flavin mononucleotide-dependent NADPH-oxidation activity and arresting essential fatty acid biosynthesis.

For research use only. We do not sell to patients.

NPD6433 Chemical Structure

NPD6433 Chemical Structure

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NPD6433 Related Antibodies

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Description

NPD6433 is a triazenyl indole with broad-spectrum activity against all screening fungal strains. NPD6433 targets the enoyl reductase domain of fatty acid synthase 1 (Fas1), covalently inhibiting its flavin mononucleotide-dependent NADPH-oxidation activity and arresting essential fatty acid biosynthesis[1].

Molecular Weight

391.42

Formula

C21H21N5O3
SMILES

O=C(C1=C(/N=N/N2C[C@@H]3C4=CC=CC(N4C[C@@H](C3)C2)=O)C5=C(C=CC=C5)N1)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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NPD6433 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NPD6433NPD 6433NPD-6433FungalFatty Acid Synthase (FASN)fungalNADPHFas1Inhibitorinhibitorinhibit

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