2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. Ro 8-4304

Ro 8-4304 is a non-competitive, voltage-independent and state-dependent antagonist for NMDA receptor. Ro 8-4304 inhibits 10 μM NMDA-induced currents and 100 μM NMDA-induced currents with IC50s of 2.3 μM and 0.36 μM.

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Ro 8-4304 Chemical Structure

Ro 8-4304 Chemical Structure

CAS No. : 195988-65-9

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Ro 8-4304 Related Antibodies

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Description

Ro 8-4304 is a non-competitive, voltage-independent and state-dependent antagonist for NMDA receptor. Ro 8-4304 inhibits 10 μM NMDA-induced currents and 100 μM NMDA-induced currents with IC50s of 2.3 μM and 0.36 μM[1].

Molecular Weight

370.42

Formula

C21H23FN2O3
CAS No.
SMILES

O=C(C1=CC=C(C=C1)OCC(CN2CC=C(CC2)C3=CC=C(F)C=C3)O)N
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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Ro 8-4304 Related Classifications

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Keywords:

Ro 8-4304195988-65-9iGluRIonotropic glutamate receptorsInhibitorinhibitorinhibit

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