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Apcdd1

" in MedChemExpress (MCE) Product Catalog:
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  • HY-P76154
    APCDD1 Protein, Human (HEK293, Fc)

    Adenomatosis polyposis coli down-regulated 1 protein; DRAPC1; HYPT1

    		 Human HEK293
    The APCDD1 protein inhibits the Wnt signaling pathway and its mutations are associated with hereditary hypotrichosis simplex, causing hair loss. Increased expression of APCDD1 may be related to colorectal cancer development. The gene is highly expressed in the skin (RPKM 30.0), fat (RPKM 14.2), and 13 other tissues. APCDD1 Protein, Human (HEK293, Fc) is the recombinant human-derived APCDD1 protein, expressed by HEK293 , with C-hFc labeled tag.
  • HY-P701326
    APCDD1 Protein, Human (466a.a, HEK293, Fc)

    Adenomatosis polyposis coli down-regulated 1 protein; DRAPC1; HYPT1

    		 Human HEK293
    APCDD1 protein, a homodimer, negatively regulates the Wnt signaling pathway, acting cell-autonomously upstream of beta-catenin. Implicated in colorectal tumorigenesis, it interacts with LRP5 and WNT3A, suggesting involvement in complex interactions with Wnt and LRP proteins. APCDD1's pivotal role is evident in its contribution to intricate regulatory mechanisms governing Wnt signaling. APCDD1 Protein, Human (466a.a, HEK293, Fc) is the recombinant human-derived APCDD1 protein, expressed by HEK293, with C-hFc labeled tag. The total length of APCDD1 Protein, Human (466a.a, HEK293, Fc) is 466 a.a., with molecular weight of 82-110 kDa.

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