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DMS53

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-170368
    3′-Me Meayamycin D

    		SF3B1 Cancer
    3’-Me Meayamycin D is a splicing modulator on SF3B1 and PHF5A, that affects the pre-mRNA splicing process, and downregulates the MCL-1 expression. 3’-Me Meayamycin D inhibits the proliferation of cancer cell HCT116, SW48, A549, DMS53 and DMS114 with GI50 of 4.6-7.2 nM. 3’-Me Meayamycin D exhibits good plasma stability in mice with a halt-life of 16 h .
    3′-Me Meayamycin D

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