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DTS

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Cytotoxin (1) Aminopeptidase (1) Antibody-Drug Conjugates (ADCs) (1) Cathepsin (1) Peptide-Drug Conjugate (PDC) (2) Topoisomerase (1)
By Research Areas:	Cancer (3)

3

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2

Peptides

1

Natural
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4

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1

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Dibenzyl trisulfide DTS	Cathepsin	Cancer
Dibenzyl trisulfide (DTS) is an active ingredient that can be isolated from Petiveria alliacea L.. Dibenzyl trisulfide inhibits cell proliferation and migration. Dibenzyl trisulfide decreased the mRNA and protein expression of BAK-1 and LTA. Dibenzyl trisulfide induces lysosomal membrane permeabilization and cathepsin B release .

DTS-108	Peptide-Drug Conjugate (PDC) Topoisomerase Antibody-Drug Conjugates (ADCs)	Cancer
DTS-108 is a prodrug of SN38 (HY-13704) (a Topoisomerase I inhibitor). DTS-108 is a conjugate generated by linking SN38 to a human oligopeptide via an esterase sensitive cross-linker. DTS-108 exhibits anti-tumor activity against colorectal, lung, and mammary cancer .

DTS-201 sodium	Peptide-Drug Conjugate (PDC) Aminopeptidase ADC Cytotoxin	Cancer
DTS-201 sodium (CPI-0004Na) is a peptidic prodrug of Doxorubicin (HY-15142A). DTS-201, comprising the tetrapeptide portion, is cleaved by endopeptidases in the tumor environment to produce metabolites that subsequently enter the cell and are converted to active Doxorubicin. DTS-201 shows antitumoral efficacy in tumor xenograft models of prostate, breast, and lung cancer .

Cat. No.	Product Name	Target	Research Area

DTS-108	Peptide-Drug Conjugate (PDC) Topoisomerase Antibody-Drug Conjugates (ADCs)	Cancer
DTS-108 is a prodrug of SN38 (HY-13704) (a Topoisomerase I inhibitor). DTS-108 is a conjugate generated by linking SN38 to a human oligopeptide via an esterase sensitive cross-linker. DTS-108 exhibits anti-tumor activity against colorectal, lung, and mammary cancer .

DTS-201 sodium	Peptide-Drug Conjugate (PDC) Aminopeptidase ADC Cytotoxin	Cancer
DTS-201 sodium (CPI-0004Na) is a peptidic prodrug of Doxorubicin (HY-15142A). DTS-201, comprising the tetrapeptide portion, is cleaved by endopeptidases in the tumor environment to produce metabolites that subsequently enter the cell and are converted to active Doxorubicin. DTS-201 shows antitumoral efficacy in tumor xenograft models of prostate, breast, and lung cancer .

Species:	Human (4)
Tag:	His (1) Tag Free (3)
Source:	HEK293 (1) CHO (1) Sf9 insect cells (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

	HB-EGF Protein, Human (HEK293, His) Proheparin-binding EGF-like growth factor; HB-EGF; DT-R; DTS; HEGFL	Human	HEK293
	HB-EGF protein is a multifunctional growth factor that is regulated through EGFR, ERBB2 and ERBB4 and is critical for cardiac valve formation and cardiac function. It promotes smooth muscle cell proliferation and may contribute to macrophage-mediated cell proliferation. HB-EGF Protein, Human (HEK293, His) is the recombinant human-derived HB-EGF protein, expressed by HEK293 , with C-6*His labeled tag. The total length of HB-EGF Protein, Human (HEK293, His) is 129 a.a., with molecular weight of ~18 kDa.

	HB-EGF Protein, Human (CHO) 2 Publications Verification rHuProheparin-binding EGF-like Growth Factor; DTR; DTS; HEGFL	Human	CHO
	HB-EGF Protein, Human (CHO) is shown to play a role in wound healing, cardiac hypertrophy, and heart development and function.

	HB-EGF Protein, Human rHuHB-EGF; HBEGF; Diphtheria toxin receptor; DTR	Human	E. coli
	HB-EGF Protein, Human is a member of the epidermal growth factor (EGF) family of growth factors that stimulate growth and differentiation.

	HB-EGF Protein, Human (sf9) Proheparin-binding EGF-like Growth Factor; DTR; DTS; HEGFL; HBEGF	Human	Sf9 insect cells
	HB-EGF protein is a multifunctional growth factor that is regulated through EGFR, ERBB2 and ERBB4 and is critical for cardiac valve formation and cardiac function. It promotes smooth muscle cell proliferation and may contribute to macrophage-mediated cell proliferation. HB-EGF Protein, Human (sf9) is the recombinant human-derived HB-EGF protein, expressed by Sf9 insect cells , with tag free. The total length of HB-EGF Protein, Human (sf9) is 86 a.a., with molecular weight of ~16.4 kDa.

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	HBEGF Antibody (YA1801) DTR; DTS; DTSF; HB-EGF; HBEGF; HEGFL	WB	Human, Rat
	HBEGF Antibody (YA1801) is a biotin-conjugated non-conjugated IgG antibody, targeting HBEGF, with a predicted molecular weight of 23 kDa (observed band size: 23 kDa). HBEGF Antibody (YA1801) can be used for WB experiment in human, rat background.

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