2. Metabolic Enzyme/Protease
  3. Cathepsin
  4. Dibenzyl trisulfide

Dibenzyl trisulfide (DTS) is an active ingredient that can be isolated from Petiveria alliacea L.. Dibenzyl trisulfide inhibits cell proliferation and migration. Dibenzyl trisulfide decreased the mRNA and protein expression of BAK-1 and LTA. Dibenzyl trisulfide induces lysosomal membrane permeabilization and cathepsin B release.

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Dibenzyl trisulfide Chemical Structure

Dibenzyl trisulfide Chemical Structure

CAS No. : 6493-73-8

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Dibenzyl trisulfide Related Antibodies

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Description

Dibenzyl trisulfide (DTS) is an active ingredient that can be isolated from Petiveria alliacea L.. Dibenzyl trisulfide inhibits cell proliferation and migration. Dibenzyl trisulfide decreased the mRNA and protein expression of BAK-1 and LTA. Dibenzyl trisulfide induces lysosomal membrane permeabilization and cathepsin B release[1].

In Vitro

Dibenzyl trisulfide (0.1-50 µM; 2 weeks) inhibits CRL-2335 cell proliferation and migration[1].
Dibenzyl trisulfide (10, 50 µM; 48 h) decreased the mRNA and protein expression of BAK-1 and LTA in a dose-dependent manner[1].
Dibenzyl trisulfide (10 µM; 48 h) induces lysosomal membrane permeabilization and cathepsin B release in CRL-2335 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Dibenzyl trisulfide Related Antibodies

Cell Proliferation Assay[1]

Cell Line: CRL-2335 cells
Concentration: 0.1, 0.5, 1, 10, 50 µM
Incubation Time: 2 weeks
Result: Inhibited proliferation and migration of CRL-2335 cell in a dose-dependent manner.

RT-PCR[1]

Cell Line: CRL-2335 cells
Concentration: 0, 10, 50 µM
Incubation Time: 48 h
Result: Decreased the mRNA expression of BAK-1, GADD45a, and LTA in a dose-dependent manner.

Immunofluorescence[1]

Cell Line: CRL-2335 cells
Concentration: 0, 10, 50 µM
Incubation Time: 48 h
Result: Decreased the protein expression of BAK-1 and LTA but not GADD45a.
Molecular Weight

278.46

Formula

C14H14S3
CAS No.
SMILES

C1(CSSSCC2=CC=CC=C2)=CC=CC=C1
Structure Classification
Initial Source
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Please store the product under the recommended conditions in the Certificate of Analysis.
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References
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Dibenzyl trisulfide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dibenzyl trisulfide6493-73-8DTSCathepsinRL-2335 cellsBAK-1LTAcathepsin BInhibitorinhibitorinhibit

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